Gene name: MDR1
Reference locus (S288C): YGR100W
Gene biotype: protein_coding
Description: Cytoplasmic GTPase-activating protein; activates Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function
Top 10 interactors (score): STE6 (0.947); GYP1 (0.911); GYP7 (0.91); GYP8 (0.908); YPT31 (0.869); YPT32 (0.827); SEC4 (0.819); GYP6 (0.812); HMLALPHA2 (0.78); MATALPHA2 (0.78); ERG11 (0.778); PDR5 (0.776); PDR1 (0.749); YPT6 (0.749); NOP14 (0.744); ARF3 (0.729); QDR1 (0.715); PDR3 (0.697); YPT1 (0.684); RHO1 (0.68)
Homologues (species, bitscore): TBC1D8 (Homo sapiens, 260.4); Tbc1d9 (Mus musculus, 257.7); TBC1D8B (Danio rerio, 247.7); tbc1d8 (Xenopus tropicalis, 255.0); CG7324 (Drosophila melanogaster, 226.5); tbc-9 (Caenorhabditis elegans, 224.2); AT3G55020 (Arabidopsis thaliana, 157.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:674425-677277:+ | gene-YGR100W_AKU4011 | rna-NM_001181229.1_AKU4011 | cds-NP_011614.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:110286-113138:+ | gene-YGR100W_BG1 | rna-NM_001181229.1_BG1 | cds-NP_011614.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:676617-679469:+ | gene-YGR100W_Bruggeman | rna-NM_001181229.1_Bruggeman | cds-NP_011614.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:674806-677658:+ | gene-YGR100W_CAT1 | rna-NM_001181229.1_CAT1 | cds-NP_011614.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:675388-678240:+ | gene-YGR100W_CBS1585 | rna-NM_001181229.1_CBS1585 | cds-NP_011614.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:677048-679900:+ | gene-YGR100W_CBS436 | rna-NM_001181229.1_CBS436 | cds-NP_011614.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:667092-669944:+ | gene-YGR100W_CBS6412 | rna-NM_001181229.1_CBS6412 | cds-NP_011614.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:672025-674877:+ | gene-YGR100W_CBS6413 | rna-NM_001181229.1_CBS6413 | cds-NP_011614.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:689918-692770:+ | gene-YGR100W_CENPK1137D | rna-NM_001181229.1_CENPK1137D | cds-NP_011614.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:662015-664867:+ | gene-YGR100W_EthanolRed | rna-NM_001181229.1_EthanolRed | cds-NP_011614.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:665823-668675:+ | gene-YGR100W_FaliES1 | rna-NM_001181229.1_FaliES1 | cds-NP_011614.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000396.1:7878-10730:- | gene-YGR100W_JAY291 | rna-NM_001181229.1_JAY291 | cds-NP_011614.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:673606-676458:+ | gene-YGR100W_MUCL30387 | rna-NM_001181229.1_MUCL30387 | cds-NP_011614.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:676417-679269:+ | gene-YGR100W_MUCL30388 | rna-NM_001181229.1_MUCL30388 | cds-NP_011614.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:671119-673971:+ | gene-YGR100W_MUCL39482 | rna-NM_001181229.1_MUCL39482 | cds-NP_011614.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:681429-684281:+ | gene-YGR100W_MUCL42920 | rna-NM_001181229.1_MUCL42920 | cds-NP_011614.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:690245-693097:+ | gene-YGR100W_NCIM3186 | rna-NM_001181229.1_NCIM3186 | cds-NP_011614.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:665808-668660:+ | gene-YGR100W_NCYC1407 | rna-NM_001181229.1_NCYC1407 | cds-NP_011614.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:668496-671348:+ | gene-YGR100W_PE2H3 | rna-NM_001181229.1_PE2H3 | cds-NP_011614.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:673615-676467:+ | gene-YGR100W_PE2H4 | rna-NM_001181229.1_PE2H4 | cds-NP_011614.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:690245-693097:+ | gene-YGR100W_S288C | rna-NM_001181229.1_S288C | cds-NP_011614.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:116854-119706:+ | gene-YGR100W_SA1 | rna-NM_001181229.1_SA1 | cds-NP_011614.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:686192-689044:+ | gene-YGR100W_ThermosaccDry | rna-NM_001181229.1_ThermosaccDry | cds-NP_011614.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:782684-785536:+ | gene-YGR100W_VR1 | rna-NM_001181229.1_VR1 | cds-NP_011614.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:140440-143292:+ | gene-YGR100W_ZTW1 | rna-NM_001181229.1_ZTW1 | cds-NP_011614.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:676208-679060:+ | gene-YGR100W_Sparadoxus | rna-NM_001181229.1_Sparadoxus | cds-NP_011614.1_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |