Gene name: MDM38
Reference locus (S288C): YOL027C
Gene biotype: protein_coding
Description: Mitochondrial distribution and morphology protein 38; Mitochondrial protein; forms a complex with Mba1p to facilitate recruitment of mRNA-specific translational activators to ribosomes; roles in protein export and K+/H+ exchange; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome
Top 10 interactors (score): MBA1 (0.961); OXA1 (0.919); KHA1 (0.896); PUF3 (0.863); VNX1 (0.863); MRS2 (0.841); YDL183C (0.813); FMC1 (0.794); COX18 (0.75); TOM22 (0.735); RBG2 (0.722); ATP6 (0.721); ATG32 (0.695); NHX1 (0.691); MRPL22 (0.677); YME1 (0.677); UTH1 (0.671); PAM18 (0.664); TIM44 (0.663); COX2 (0.65)
Homologues (species, bitscore): LETM1 (Homo sapiens, 223.8); Letm1 (Mus musculus, 221.9); letm1 (Danio rerio, 228.0); letm2 (Xenopus tropicalis, 203.8); Letm1 (Drosophila melanogaster, 231.1); letm-1 (Caenorhabditis elegans, 218.4); LETM2 (Arabidopsis thaliana, 228.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:256399-258120:- | gene-YOL027C_AKU4011 | rna-NM_001183281.1_AKU4011 | cds-NP_014615.1_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000152.1:71985-73706:- | gene-YOL027C_BG1 | rna-NM_001183281.1_BG1 | cds-NP_014615.1_BG1 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:259218-260939:- | gene-YOL027C_Bruggeman | rna-NM_001183281.1_Bruggeman | cds-NP_014615.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:257092-258813:- | gene-YOL027C_CAT1 | rna-NM_001183281.1_CAT1 | cds-NP_014615.1_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:251077-252798:- | gene-YOL027C_CBS1585 | rna-NM_001183281.1_CBS1585 | cds-NP_014615.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:255311-257032:- | gene-YOL027C_CBS436 | rna-NM_001183281.1_CBS436 | cds-NP_014615.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:250433-252154:- | gene-YOL027C_CBS6412 | rna-NM_001183281.1_CBS6412 | cds-NP_014615.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:257959-259680:- | gene-YOL027C_CBS6413 | rna-NM_001183281.1_CBS6413 | cds-NP_014615.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:271703-273424:- | gene-YOL027C_CENPK1137D | rna-NM_001183281.1_CENPK1137D | cds-NP_014615.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:253226-254947:- | gene-YOL027C_EthanolRed | rna-NM_001183281.1_EthanolRed | cds-NP_014615.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:256304-258025:- | gene-YOL027C_FaliES1 | rna-NM_001183281.1_FaliES1 | cds-NP_014615.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000018.1:8468-10189:+ | gene-YOL027C_JAY291 | rna-NM_001183281.1_JAY291 | cds-NP_014615.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:262257-263978:- | gene-YOL027C_MUCL30387 | rna-NM_001183281.1_MUCL30387 | cds-NP_014615.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:266595-268316:- | gene-YOL027C_MUCL30388 | rna-NM_001183281.1_MUCL30388 | cds-NP_014615.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:258562-260283:- | gene-YOL027C_MUCL39482 | rna-NM_001183281.1_MUCL39482 | cds-NP_014615.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:273476-275197:- | gene-YOL027C_MUCL42920 | rna-NM_001183281.1_MUCL42920 | cds-NP_014615.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:271892-273613:- | gene-YOL027C_NCIM3186 | rna-NM_001183281.1_NCIM3186 | cds-NP_014615.1_NCIM3186 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:265294-267015:- | gene-YOL027C_NCYC1407 | rna-NM_001183281.1_NCYC1407 | cds-NP_014615.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:247679-249400:- | gene-YOL027C_PE2H3 | rna-NM_001183281.1_PE2H3 | cds-NP_014615.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:258653-260374:- | gene-YOL027C_PE2H4 | rna-NM_001183281.1_PE2H4 | cds-NP_014615.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:272003-273724:- | gene-YOL027C_S288C | rna-NM_001183281.1_S288C | cds-NP_014615.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:240003-241724:- | gene-YOL027C_SA1 | rna-NM_001183281.1_SA1 | cds-NP_014615.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:254875-256596:- | gene-YOL027C_ThermosaccDry | rna-NM_001183281.1_ThermosaccDry | cds-NP_014615.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:254904-256625:- | gene-YOL027C_VR1 | rna-NM_001183281.1_VR1 | cds-NP_014615.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:254720-256441:- | gene-YOL027C_ZTW1 | rna-NM_001183281.1_ZTW1 | cds-NP_014615.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:263114-264835:- | gene-YOL027C_Sparadoxus | rna-NM_001183281.1_Sparadoxus | cds-NP_014615.1_Sparadoxus | 90.9 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |