Gene name: MDM35
Reference locus (S288C): YKL053C-A
Gene biotype: protein_coding
Description: Mitochondrial distribution and morphology protein 35; Mitochondrial intermembrane space protein; forms complex with Ups2p that transfers phosphatidylserine from outer membrane to inner membrane for phosphatidylethanolamine synthesis; mutation affects mitochondrial distribution and morphology; contains twin cysteine-x9-cysteine motifs; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): UPS1 (0.999); UPS2 (0.999); COX17 (0.99); COX19 (0.989); MIA40 (0.984); TIM9 (0.978); TIM10 (0.977); MIX17 (0.977); MIX14 (0.977); UPS3 (0.971); TIM8 (0.965); TIM13 (0.961); ERV1 (0.959); COA4 (0.933); CMC2 (0.913); COA6 (0.913); CCS1 (0.903); VMA7 (0.896); SMX2 (0.896); SRB7 (0.894)
Homologues (species, bitscore): TRIAP1 (Homo sapiens, 55.5); Triap1 (Mus musculus, 54.3); triap1 (Danio rerio, 56.6); triap1 (Xenopus tropicalis, 57.0); CG30108 (Drosophila melanogaster, 55.5); AT4G33100 (Arabidopsis thaliana, 52.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:325178-325438:- | gene-YKL053C-A_AKU4011 | rna-NM_001184336.1_AKU4011 | cds-NP_012870.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:318570-318830:+ | gene-YKL053C-A_BG1 | rna-NM_001184336.1_BG1 | cds-NP_012870.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:344209-344469:- | gene-YKL053C-A_Bruggeman | rna-NM_001184336.1_Bruggeman | cds-NP_012870.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:340637-340897:- | gene-YKL053C-A_CAT1 | rna-NM_001184336.1_CAT1 | cds-NP_012870.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:337908-338168:- | gene-YKL053C-A_CBS1585 | rna-NM_001184336.1_CBS1585 | cds-NP_012870.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:336040-336300:- | gene-YKL053C-A_CBS436 | rna-NM_001184336.1_CBS436 | cds-NP_012870.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:322042-322302:- | gene-YKL053C-A_CBS6412 | rna-NM_001184336.1_CBS6412 | cds-NP_012870.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:337870-338130:- | gene-YKL053C-A_CBS6413 | rna-NM_001184336.1_CBS6413 | cds-NP_012870.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:338842-339102:- | gene-YKL053C-A_CENPK1137D | rna-NM_001184336.1_CENPK1137D | cds-NP_012870.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:335863-336123:- | gene-YKL053C-A_EthanolRed | rna-NM_001184336.1_EthanolRed | cds-NP_012870.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:336676-336936:- | gene-YKL053C-A_FaliES1 | rna-NM_001184336.1_FaliES1 | cds-NP_012870.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000080.1:41601-41861:- | gene-YKL053C-A_JAY291 | rna-NM_001184336.1_JAY291 | cds-NP_012870.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:345110-345370:- | gene-YKL053C-A_MUCL30387 | rna-NM_001184336.1_MUCL30387 | cds-NP_012870.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:339999-340259:- | gene-YKL053C-A_MUCL30388 | rna-NM_001184336.1_MUCL30388 | cds-NP_012870.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:337204-337464:- | gene-YKL053C-A_MUCL39482 | rna-NM_001184336.1_MUCL39482 | cds-NP_012870.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:342059-342319:- | gene-YKL053C-A_MUCL42920 | rna-NM_001184336.1_MUCL42920 | cds-NP_012870.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:339171-339431:- | gene-YKL053C-A_NCIM3186 | rna-NM_001184336.1_NCIM3186 | cds-NP_012870.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:337400-337660:- | gene-YKL053C-A_NCYC1407 | rna-NM_001184336.1_NCYC1407 | cds-NP_012870.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:361943-362203:- | gene-YKL053C-A_PE2H3 | rna-NM_001184336.1_PE2H3 | cds-NP_012870.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:346683-346943:- | gene-YKL053C-A_PE2H4 | rna-NM_001184336.1_PE2H4 | cds-NP_012870.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:339182-339442:- | gene-YKL053C-A_S288C | rna-NM_001184336.1_S288C | cds-NP_012870.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:17284-17544:- | gene-YKL053C-A_SA1 | rna-NM_001184336.1_SA1 | cds-NP_012870.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:337866-338126:- | gene-YKL053C-A_ThermosaccDry | rna-NM_001184336.1_ThermosaccDry | cds-NP_012870.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:337012-337272:- | gene-YKL053C-A_VR1 | rna-NM_001184336.1_VR1 | cds-NP_012870.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:335894-336154:- | gene-YKL053C-A_ZTW1 | rna-NM_001184336.1_ZTW1 | cds-NP_012870.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:355097-355357:- | gene-YKL053C-A_Sparadoxus | rna-NM_001184336.1_Sparadoxus | cds-NP_012870.1_Sparadoxus | 93.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |