MDM10 (YAL010C)


Gene profile

Gene name: MDM10
Reference locus (S288C): YAL010C
Gene biotype: protein_coding

Description: Mitochondrial distribution and morphology protein 10; Subunit of both the ERMES and the SAM complex; component of ERMES complex which acts as a molecular tether between the mitochondria and the ER, necessary for efficient phospholipid exchange between organelles and for mitophagy; SAM/TOB complex component that functions in the assembly of outer membrane beta-barrel proteins; involved in mitochondrial inheritance and morphology; ERMES complex is often co-localized with peroxisomes and concentrated areas of pyruvate dehydrogenase; Belongs to the MDM10 family

Top 10 interactors (score): MMM1 (0.999); TOM40 (0.999); MDM34 (0.999); SAM50 (0.999); MDM12 (0.999); GEM1 (0.999); SAM37 (0.998); SAM35 (0.996); TOM22 (0.994); TOM7 (0.993); TOM70 (0.98); TOM20 (0.96); DNM1 (0.95); TIM13 (0.932); TOM6 (0.931); TOM5 (0.929); TIM8 (0.919); POR1 (0.914); FZO1 (0.914); MCP1 (0.913)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005295.1:119296-120777:- gene-YAL010C_AKU4011 rna-NM_001178155.2_AKU4011 cds-NP_009392.2_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000070.1:106246-107727:- gene-YAL010C_BG1 rna-NM_001178155.2_BG1 cds-NP_009392.2_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005503.1:134169-135650:- gene-YAL010C_Bruggeman rna-NM_001178155.2_Bruggeman cds-NP_009392.2_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005519.1:120506-121987:- gene-YAL010C_CAT1 rna-NM_001178155.2_CAT1 cds-NP_009392.2_CAT1 99.0 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005359.1:132308-133789:- gene-YAL010C_CBS1585 rna-NM_001178155.2_CBS1585 cds-NP_009392.2_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005343.1:132586-134067:- gene-YAL010C_CBS436 rna-NM_001178155.2_CBS436 cds-NP_009392.2_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:745402-746883:- gene-YAL010C_CBS6412 rna-NM_001178155.2_CBS6412 cds-NP_009392.2_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005311.1:130578-132059:- gene-YAL010C_CBS6413 rna-NM_001178155.2_CBS6413 cds-NP_009392.2_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001522.1:134344-135825:- gene-YAL010C_CENPK1137D rna-NM_001178155.2_CENPK1137D cds-NP_009392.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005471.1:120715-122196:- gene-YAL010C_EthanolRed rna-NM_001178155.2_EthanolRed cds-NP_009392.2_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005535.1:135342-136823:- gene-YAL010C_FaliES1 rna-NM_001178155.2_FaliES1 cds-NP_009392.2_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000084.1:106613-108094:- gene-YAL010C_JAY291 rna-NM_001178155.2_JAY291 cds-NP_009392.2_JAY291 99.0 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005407.1:135322-136803:- gene-YAL010C_MUCL30387 rna-NM_001178155.2_MUCL30387 cds-NP_009392.2_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005439.1:132569-134050:- gene-YAL010C_MUCL30388 rna-NM_001178155.2_MUCL30388 cds-NP_009392.2_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005279.1:131090-132571:- gene-YAL010C_MUCL39482 rna-NM_001178155.2_MUCL39482 cds-NP_009392.2_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005423.1:133471-134952:- gene-YAL010C_MUCL42920 rna-NM_001178155.2_MUCL42920 cds-NP_009392.2_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011810.1:134061-135542:- gene-YAL010C_NCIM3186 rna-NM_001178155.2_NCIM3186 cds-NP_009392.2_NCIM3186 98.9 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005263.1:118973-120454:- gene-YAL010C_NCYC1407 rna-NM_001178155.2_NCYC1407 cds-NP_009392.2_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994140.1:120901-122382:- gene-YAL010C_PE2H3 rna-NM_001178155.2_PE2H3 cds-NP_009392.2_PE2H3 99.0 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999872.1:120620-122101:- gene-YAL010C_PE2H4 rna-NM_001178155.2_PE2H4 cds-NP_009392.2_PE2H4 99.0 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001133.9:134184-135665:- gene-YAL010C_S288C rna-NM_001178155.2_S288C cds-NP_009392.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000077.1:51105-52586:- gene-YAL010C_SA1 rna-NM_001178155.2_SA1 cds-NP_009392.2_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005487.1:134834-136315:- gene-YAL010C_ThermosaccDry rna-NM_001178155.2_ThermosaccDry cds-NP_009392.2_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005455.1:136144-137625:- gene-YAL010C_VR1 rna-NM_001178155.2_VR1 cds-NP_009392.2_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000002.1:106662-108143:- gene-YAL010C_ZTW1 rna-NM_001178155.2_ZTW1 cds-NP_009392.2_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047487.1:124182-125663:- gene-YAL010C_Sparadoxus rna-NM_001178155.2_Sparadoxus cds-NP_009392.2_Sparadoxus 89.8 100.0 Verified 1 1 1 False True False False False

Additional files