MDL1 (YLR188W)


Gene profile

Gene name: MDL1
Reference locus (S288C): YLR188W
Gene biotype: protein_coding

Description: ATP-dependent permease MDL1, mitochondrial; Mitochondrial inner membrane half-type ABC transporter; mediates export of peptides generated upon proteolysis of mitochondrial proteins; plays a role in the regulation of cellular resistance to oxidative stress

Top 10 interactors (score): YDR061W (0.739); RLI1 (0.692); YME1 (0.682); HEM15 (0.669); HEM14 (0.654); HEM1 (0.637); LSC2 (0.618); MMT2 (0.618); ATM1 (0.607); HEM12 (0.589); MMT1 (0.581); HEM2 (0.571); HEM4 (0.556); YJR085C (0.549); OXA1 (0.542); MRPL25 (0.523); GTS1 (0.513); BCS1 (0.513); PTR2 (0.492); SSC1 (0.491)

Homologues (species, bitscore): ABCB10 (Homo sapiens, 458.8); Abcb10 (Mus musculus, 458.4); abcb10 (Danio rerio, 453.8); abcb10 (Xenopus tropicalis, 359.0); CG3156 (Drosophila melanogaster, 409.8); haf-3 (Caenorhabditis elegans, 409.1); ABCB27 (Arabidopsis thaliana, 372.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:482419-484506:+ gene-YLR188W_AKU4011 rna-NM_001182075.1_AKU4011 cds-NP_013289.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000177.1:39600-41687:+ gene-YLR188W_BG1 rna-NM_001182075.1_BG1 cds-NP_013289.1_BG1 99.3 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:522669-524756:+ gene-YLR188W_Bruggeman rna-NM_001182075.1_Bruggeman cds-NP_013289.1_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:522264-524351:+ gene-YLR188W_CAT1 rna-NM_001182075.1_CAT1 cds-NP_013289.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:517916-520003:+ gene-YLR188W_CBS1585 rna-NM_001182075.1_CBS1585 cds-NP_013289.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:508056-510143:+ gene-YLR188W_CBS436 rna-NM_001182075.1_CBS436 cds-NP_013289.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:486473-488560:+ gene-YLR188W_CBS6412 rna-NM_001182075.1_CBS6412 cds-NP_013289.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:518208-520295:+ gene-YLR188W_CBS6413 rna-NM_001182075.1_CBS6413 cds-NP_013289.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:512948-515035:+ gene-YLR188W_CENPK1137D rna-NM_001182075.1_CENPK1137D cds-NP_013289.1_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:481946-484033:+ gene-YLR188W_EthanolRed rna-NM_001182075.1_EthanolRed cds-NP_013289.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:510873-512960:+ gene-YLR188W_FaliES1 rna-NM_001182075.1_FaliES1 cds-NP_013289.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000004.1:37773-39860:+ gene-YLR188W_JAY291 rna-NM_001182075.1_JAY291 cds-NP_013289.1_JAY291 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:522690-524777:+ gene-YLR188W_MUCL30387 rna-NM_001182075.1_MUCL30387 cds-NP_013289.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:527622-529709:+ gene-YLR188W_MUCL30388 rna-NM_001182075.1_MUCL30388 cds-NP_013289.1_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:518897-520984:+ gene-YLR188W_MUCL39482 rna-NM_001182075.1_MUCL39482 cds-NP_013289.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:519394-521481:+ gene-YLR188W_MUCL42920 rna-NM_001182075.1_MUCL42920 cds-NP_013289.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:528274-530361:+ gene-YLR188W_NCIM3186 rna-NM_001182075.1_NCIM3186 cds-NP_013289.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:511324-513411:+ gene-YLR188W_NCYC1407 rna-NM_001182075.1_NCYC1407 cds-NP_013289.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:515562-517649:+ gene-YLR188W_PE2H3 rna-NM_001182075.1_PE2H3 cds-NP_013289.1_PE2H3 99.4 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:515306-517393:+ gene-YLR188W_PE2H4 rna-NM_001182075.1_PE2H4 cds-NP_013289.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:528300-530387:+ gene-YLR188W_S288C rna-NM_001182075.1_S288C cds-NP_013289.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000042.1:37831-39918:+ gene-YLR188W_SA1 rna-NM_001182075.1_SA1 cds-NP_013289.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:513376-515463:+ gene-YLR188W_ThermosaccDry rna-NM_001182075.1_ThermosaccDry cds-NP_013289.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:524675-526762:+ gene-YLR188W_VR1 rna-NM_001182075.1_VR1 cds-NP_013289.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000024.1:37665-39752:+ gene-YLR188W_ZTW1 rna-NM_001182075.1_ZTW1 cds-NP_013289.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:499502-501589:+ gene-YLR188W_Sparadoxus rna-NM_001182075.1_Sparadoxus cds-NP_013289.1_Sparadoxus 90.1 100.0 Verified 1 1 1 False True False False False

Additional files