MDJ1 (YFL016C)


Gene profile

Gene name: MDJ1
Reference locus (S288C): YFL016C
Gene biotype: protein_coding

Description: DnaJ homolog 1, mitochondrial; Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones

Top 10 interactors (score): SSC1 (0.999); MGE1 (0.999); ECM10 (0.998); TIM44 (0.994); HSP78 (0.992); SSE2 (0.988); SIS1 (0.978); SSE1 (0.975); SSQ1 (0.973); SSA2 (0.972); SSA4 (0.97); SSA1 (0.966); SSA3 (0.963); HSP60 (0.959); PAM18 (0.957); JAC1 (0.951); MDJ2 (0.903); HSP10 (0.897); PIM1 (0.897); HSP104 (0.891)

Homologues (species, bitscore): DNAJA3 (Homo sapiens, 186.4); Dnaja3 (Mus musculus, 186.4); dnaja3a (Danio rerio, 190.3); dnaja3 (Xenopus tropicalis, 199.9); l(2)tid (Drosophila melanogaster, 186.8); dnj-10 (Caenorhabditis elegans, 197.6); AT2G22360 (Arabidopsis thaliana, 221.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:101139-102674:- gene-YFL016C_AKU4011 rna-NM_001179950.1_AKU4011 cds-NP_116638.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000203.1:4300-5835:+ gene-YFL016C_BG1 rna-NM_001179950.1_BG1 cds-NP_116638.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:100461-101996:- gene-YFL016C_Bruggeman rna-NM_001179950.1_Bruggeman cds-NP_116638.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:106128-107663:- gene-YFL016C_CAT1 rna-NM_001179950.1_CAT1 cds-NP_116638.1_CAT1 99.3 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:101965-103500:- gene-YFL016C_CBS1585 rna-NM_001179950.1_CBS1585 cds-NP_116638.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:76136-77671:- gene-YFL016C_CBS436 rna-NM_001179950.1_CBS436 cds-NP_116638.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:101703-103238:- gene-YFL016C_CBS6412 rna-NM_001179950.1_CBS6412 cds-NP_116638.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:104217-105752:- gene-YFL016C_CBS6413 rna-NM_001179950.1_CBS6413 cds-NP_116638.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:101035-102570:- gene-YFL016C_CENPK1137D rna-NM_001179950.1_CENPK1137D cds-NP_116638.1_CENPK1137D 99.8 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:100133-101668:- gene-YFL016C_EthanolRed rna-NM_001179950.1_EthanolRed cds-NP_116638.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:101779-103314:- gene-YFL016C_FaliES1 rna-NM_001179950.1_FaliES1 cds-NP_116638.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000449.1:3244-4779:- gene-YFL016C_JAY291 rna-NM_001179950.1_JAY291 cds-NP_116638.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:102100-103635:- gene-YFL016C_MUCL30387 rna-NM_001179950.1_MUCL30387 cds-NP_116638.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:100044-101579:- gene-YFL016C_MUCL30388 rna-NM_001179950.1_MUCL30388 cds-NP_116638.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:100392-101927:- gene-YFL016C_MUCL39482 rna-NM_001179950.1_MUCL39482 cds-NP_116638.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:99692-101227:- gene-YFL016C_MUCL42920 rna-NM_001179950.1_MUCL42920 cds-NP_116638.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:104700-106235:- gene-YFL016C_NCIM3186 rna-NM_001179950.1_NCIM3186 cds-NP_116638.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:101430-102965:- gene-YFL016C_NCYC1407 rna-NM_001179950.1_NCYC1407 cds-NP_116638.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:121277-122812:- gene-YFL016C_PE2H3 rna-NM_001179950.1_PE2H3 cds-NP_116638.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:120825-122360:- gene-YFL016C_PE2H4 rna-NM_001179950.1_PE2H4 cds-NP_116638.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:104701-106236:- gene-YFL016C_S288C rna-NM_001179950.1_S288C cds-NP_116638.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000105.1:17466-19001:- gene-YFL016C_SA1 rna-NM_001179950.1_SA1 cds-NP_116638.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:100940-102475:- gene-YFL016C_ThermosaccDry rna-NM_001179950.1_ThermosaccDry cds-NP_116638.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America MBVZ01000098.1:140-1675:- gene-YFL016C_VR1 rna-NM_001179950.1_VR1 cds-NP_116638.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:31371-32906:- gene-YFL016C_ZTW1 rna-NM_001179950.1_ZTW1 cds-NP_116638.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:125584-127116:- gene-YFL016C_Sparadoxus rna-NM_001179950.1_Sparadoxus cds-NP_116638.1_Sparadoxus 90.6 99.7 Verified 1 1 1 False True False False False

Additional files