MDH3 (YDL078C)


Gene profile

Gene name: MDH3
Reference locus (S288C): YDL078C
Gene biotype: protein_coding

Description: Peroxisomal malate dehydrogenase; catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle

Top 10 interactors (score): FUM1 (0.997); CIT2 (0.996); CIT3 (0.993); CIT1 (0.992); IDH2 (0.987); MAE1 (0.987); AAT1 (0.986); MLS1 (0.985); PYC2 (0.981); LSC1 (0.98); PCK1 (0.978); ACO1 (0.974); DAL7 (0.97); PYC1 (0.965); AAT2 (0.959); ATP3 (0.95); ATP1 (0.945); ATP2 (0.938); IDH1 (0.932); GDH2 (0.928)

Homologues (species, bitscore): MDH2 (Homo sapiens, 251.9); Mdh2 (Mus musculus, 249.6); mdh2 (Danio rerio, 256.9); mdh2 (Xenopus tropicalis, 259.6); Mdh2 (Drosophila melanogaster, 257.3); mdh-2 (Caenorhabditis elegans, 253.1); MDH (Arabidopsis thaliana, 245.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:299955-300986:- gene-YDL078C_AKU4011 rna-NM_001180137.1_AKU4011 cds-NP_010205.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:248942-249973:+ gene-YDL078C_BG1 rna-NM_001180137.1_BG1 cds-NP_010205.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:317639-318670:- gene-YDL078C_Bruggeman rna-NM_001180137.1_Bruggeman cds-NP_010205.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:314130-315161:- gene-YDL078C_CAT1 rna-NM_001180137.1_CAT1 cds-NP_010205.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:298227-299258:- gene-YDL078C_CBS1585 rna-NM_001180137.1_CBS1585 cds-NP_010205.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:314908-315939:- gene-YDL078C_CBS436 rna-NM_001180137.1_CBS436 cds-NP_010205.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:296654-297685:- gene-YDL078C_CBS6412 rna-NM_001180137.1_CBS6412 cds-NP_010205.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:316280-317311:- gene-YDL078C_CBS6413 rna-NM_001180137.1_CBS6413 cds-NP_010205.1_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:314180-315211:- gene-YDL078C_CENPK1137D rna-NM_001180137.1_CENPK1137D cds-NP_010205.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:310992-312023:- gene-YDL078C_EthanolRed rna-NM_001180137.1_EthanolRed cds-NP_010205.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:316964-317995:- gene-YDL078C_FaliES1 rna-NM_001180137.1_FaliES1 cds-NP_010205.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000010.1:87033-88064:- gene-YDL078C_JAY291 rna-NM_001180137.1_JAY291 cds-NP_010205.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:315155-316186:- gene-YDL078C_MUCL30387 rna-NM_001180137.1_MUCL30387 cds-NP_010205.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:306182-307213:- gene-YDL078C_MUCL30388 rna-NM_001180137.1_MUCL30388 cds-NP_010205.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:299332-300363:- gene-YDL078C_MUCL39482 rna-NM_001180137.1_MUCL39482 cds-NP_010205.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:221342-222373:- gene-YDL078C_MUCL42920 rna-NM_001180137.1_MUCL42920 cds-NP_010205.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:315280-316311:- gene-YDL078C_NCIM3186 rna-NM_001180137.1_NCIM3186 cds-NP_010205.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:299346-300377:- gene-YDL078C_NCYC1407 rna-NM_001180137.1_NCYC1407 cds-NP_010205.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:306151-307182:- gene-YDL078C_PE2H3 rna-NM_001180137.1_PE2H3 cds-NP_010205.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:306130-307161:- gene-YDL078C_PE2H4 rna-NM_001180137.1_PE2H4 cds-NP_010205.1_PE2H4 99.6 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:315357-316388:- gene-YDL078C_S288C rna-NM_001180137.1_S288C cds-NP_010205.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000010.1:118533-119564:+ gene-YDL078C_SA1 rna-NM_001180137.1_SA1 cds-NP_010205.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:316475-317506:- gene-YDL078C_ThermosaccDry rna-NM_001180137.1_ThermosaccDry cds-NP_010205.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:318549-319580:- gene-YDL078C_VR1 rna-NM_001180137.1_VR1 cds-NP_010205.1_VR1 99.6 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:314391-315422:- gene-YDL078C_ZTW1 rna-NM_001180137.1_ZTW1 cds-NP_010205.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:316528-317559:- gene-YDL078C_Sparadoxus rna-NM_001180137.1_Sparadoxus cds-NP_010205.1_Sparadoxus 91.5 100.0 Verified 1 1 1 False True False False False

Additional files