Gene name: MDH1
Reference locus (S288C): YKL085W
Gene biotype: protein_coding
Description: Mitochondrial malate dehydrogenase; catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated; Belongs to the LDH/MDH superfamily. MDH type 1 family
Top 10 interactors (score): FUM1 (0.999); CIT1 (0.999); CIT2 (0.998); IDH2 (0.998); ACO1 (0.994); CIT3 (0.994); ATP2 (0.993); AAT1 (0.993); LSC1 (0.988); MAE1 (0.986); SDH2 (0.986); MLS1 (0.985); KGD2 (0.983); CYT1 (0.983); KGD1 (0.982); PCK1 (0.98); IDH1 (0.979); ATP3 (0.976); NDI1 (0.972); ATP1 (0.968)
Homologues (species, bitscore): MDH2 (Homo sapiens, 322.8); Mdh2 (Mus musculus, 318.2); mdh2 (Danio rerio, 318.2); mdh2 (Xenopus tropicalis, 312.8); Mdh2 (Drosophila melanogaster, 322.8); mdh-2 (Caenorhabditis elegans, 318.5); MDH (Arabidopsis thaliana, 316.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:265682-266686:+ | gene-YKL085W_AKU4011 | rna-NM_001179651.1_AKU4011 | cds-NP_012838.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000030.1:242857-243861:+ | gene-YKL085W_BG1 | rna-NM_001179651.1_BG1 | cds-NP_012838.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:283855-284859:+ | gene-YKL085W_Bruggeman | rna-NM_001179651.1_Bruggeman | cds-NP_012838.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:278655-279659:+ | gene-YKL085W_CAT1 | rna-NM_001179651.1_CAT1 | cds-NP_012838.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:277924-278928:+ | gene-YKL085W_CBS1585 | rna-NM_001179651.1_CBS1585 | cds-NP_012838.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:276517-277521:+ | gene-YKL085W_CBS436 | rna-NM_001179651.1_CBS436 | cds-NP_012838.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:262552-263556:+ | gene-YKL085W_CBS6412 | rna-NM_001179651.1_CBS6412 | cds-NP_012838.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:278380-279384:+ | gene-YKL085W_CBS6413 | rna-NM_001179651.1_CBS6413 | cds-NP_012838.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:278767-279771:+ | gene-YKL085W_CENPK1137D | rna-NM_001179651.1_CENPK1137D | cds-NP_012838.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:276376-277380:+ | gene-YKL085W_EthanolRed | rna-NM_001179651.1_EthanolRed | cds-NP_012838.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:277190-278194:+ | gene-YKL085W_FaliES1 | rna-NM_001179651.1_FaliES1 | cds-NP_012838.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:99519-100523:+ | gene-YKL085W_JAY291 | rna-NM_001179651.1_JAY291 | cds-NP_012838.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:285653-286657:+ | gene-YKL085W_MUCL30387 | rna-NM_001179651.1_MUCL30387 | cds-NP_012838.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:280049-281053:+ | gene-YKL085W_MUCL30388 | rna-NM_001179651.1_MUCL30388 | cds-NP_012838.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:277709-278713:+ | gene-YKL085W_MUCL39482 | rna-NM_001179651.1_MUCL39482 | cds-NP_012838.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:282343-283347:+ | gene-YKL085W_MUCL42920 | rna-NM_001179651.1_MUCL42920 | cds-NP_012838.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:279112-280116:+ | gene-YKL085W_NCIM3186 | rna-NM_001179651.1_NCIM3186 | cds-NP_012838.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:277903-278907:+ | gene-YKL085W_NCYC1407 | rna-NM_001179651.1_NCYC1407 | cds-NP_012838.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:284992-285996:+ | gene-YKL085W_PE2H3 | rna-NM_001179651.1_PE2H3 | cds-NP_012838.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:281279-282283:+ | gene-YKL085W_PE2H4 | rna-NM_001179651.1_PE2H4 | cds-NP_012838.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:279123-280127:+ | gene-YKL085W_S288C | rna-NM_001179651.1_S288C | cds-NP_012838.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:195253-196257:+ | gene-YKL085W_SA1 | rna-NM_001179651.1_SA1 | cds-NP_012838.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:277894-278898:+ | gene-YKL085W_ThermosaccDry | rna-NM_001179651.1_ThermosaccDry | cds-NP_012838.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:277254-278258:+ | gene-YKL085W_VR1 | rna-NM_001179651.1_VR1 | cds-NP_012838.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:276457-277461:+ | gene-YKL085W_ZTW1 | rna-NM_001179651.1_ZTW1 | cds-NP_012838.1_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:293576-294580:+ | gene-YKL085W_Sparadoxus | rna-NM_001179651.1_Sparadoxus | cds-NP_012838.1_Sparadoxus | 91.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |