MDG1 (YNL173C)


Gene profile

Gene name: MDG1
Reference locus (S288C): YNL173C
Gene biotype: protein_coding

Description: Signal transduction protein MDG1; Plasma membrane protein; involved in G-protein mediated pheromone signaling pathway; overproduction suppresses bem1 mutations; MDG1 has a paralog, CRP1, that arose from the whole genome duplication

Top 10 interactors (score): VPS34 (0.911); VPS30 (0.908); VPS15 (0.9); YNL228W (0.891); SDS24 (0.871); SNF4 (0.867); SDS23 (0.867); KIN4 (0.792); SNF1 (0.792); YPL150W (0.792); FRK1 (0.792); ATG1 (0.788); RGM1 (0.633); PRR1 (0.606); ATG13 (0.605); PPZ2 (0.601); ATG11 (0.6); INO4 (0.579); YGL036W (0.568); USV1 (0.565)

Homologues (species, bitscore): AT1G27070 (Arabidopsis thaliana, 51.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:302682-303782:- gene-YNL173C_AKU4011 rna-NM_001183011.1_AKU4011 cds-NP_014226.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:206651-207751:- gene-YNL173C_BG1 rna-NM_001183011.1_BG1 cds-NP_014226.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:312743-313843:- gene-YNL173C_Bruggeman rna-NM_001183011.1_Bruggeman cds-NP_014226.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:355620-356720:- gene-YNL173C_CAT1 rna-NM_001183011.1_CAT1 cds-NP_014226.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:303334-304434:- gene-YNL173C_CBS1585 rna-NM_001183011.1_CBS1585 cds-NP_014226.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:371658-372758:- gene-YNL173C_CBS436 rna-NM_001183011.1_CBS436 cds-NP_014226.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:298739-299839:- gene-YNL173C_CBS6412 rna-NM_001183011.1_CBS6412 cds-NP_014226.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:299767-300867:- gene-YNL173C_CBS6413 rna-NM_001183011.1_CBS6413 cds-NP_014226.1_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:302773-303873:- gene-YNL173C_CENPK1137D rna-NM_001183011.1_CENPK1137D cds-NP_014226.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:299655-300755:- gene-YNL173C_EthanolRed rna-NM_001183011.1_EthanolRed cds-NP_014226.1_EthanolRed 99.3 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:295568-296668:- gene-YNL173C_FaliES1 rna-NM_001183011.1_FaliES1 cds-NP_014226.1_FaliES1 99.3 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000260.1:21827-22927:+ gene-YNL173C_JAY291 rna-NM_001183011.1_JAY291 cds-NP_014226.1_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:308558-309658:- gene-YNL173C_MUCL30387 rna-NM_001183011.1_MUCL30387 cds-NP_014226.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:343112-344212:- gene-YNL173C_MUCL30388 rna-NM_001183011.1_MUCL30388 cds-NP_014226.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:300573-301673:- gene-YNL173C_MUCL39482 rna-NM_001183011.1_MUCL39482 cds-NP_014226.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:302979-304079:- gene-YNL173C_MUCL42920 rna-NM_001183011.1_MUCL42920 cds-NP_014226.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:308926-310026:- gene-YNL173C_NCIM3186 rna-NM_001183011.1_NCIM3186 cds-NP_014226.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:302667-303767:- gene-YNL173C_NCYC1407 rna-NM_001183011.1_NCYC1407 cds-NP_014226.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:299632-300732:- gene-YNL173C_PE2H3 rna-NM_001183011.1_PE2H3 cds-NP_014226.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:299020-300120:- gene-YNL173C_PE2H4 rna-NM_001183011.1_PE2H4 cds-NP_014226.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:308957-310057:- gene-YNL173C_S288C rna-NM_001183011.1_S288C cds-NP_014226.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000018.1:103516-104616:+ gene-YNL173C_SA1 rna-NM_001183011.1_SA1 cds-NP_014226.1_SA1 99.3 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:296425-297525:- gene-YNL173C_ThermosaccDry rna-NM_001183011.1_ThermosaccDry cds-NP_014226.1_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:314952-316052:- gene-YNL173C_VR1 rna-NM_001183011.1_VR1 cds-NP_014226.1_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:206250-207350:- gene-YNL173C_ZTW1 rna-NM_001183011.1_ZTW1 cds-NP_014226.1_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:307011-308108:- gene-YNL173C_Sparadoxus rna-NM_001183011.1_Sparadoxus cds-NP_014226.1_Sparadoxus 82.8 99.6 Verified 1 1 1 False True False False False

Additional files