Gene name: MDE1
Reference locus (S288C): YJR024C
Gene biotype: protein_coding
Description: 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant; Belongs to the aldolase class II family. MtnB subfamily
Top 10 interactors (score): UTR4 (0.999); MRI1 (0.999); ADI1 (0.981); YNL010W (0.897); MEU1 (0.876); RKI1 (0.837); GAL10 (0.727); ARO9 (0.722); ARO8 (0.698); TRP5 (0.689); TSR3 (0.673); BIR1 (0.671); DAD3 (0.626); SPE2 (0.624); XKS1 (0.619); FPR1 (0.596); RSE1 (0.594); MDN1 (0.586); TPI1 (0.579); BAT2 (0.578)
Homologues (species, bitscore): APIP (Homo sapiens, 193.4); Apip (Mus musculus, 196.1); apip (Danio rerio, 190.3); apip (Xenopus tropicalis, 199.5); CG11134 (Drosophila melanogaster, 195.3); ZC373.5 (Caenorhabditis elegans, 137.1); AT5G53850 (Arabidopsis thaliana, 161.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:453442-454176:- | gene-YJR024C_AKU4011 | rna-NM_001181682.3_AKU4011 | cds-NP_012558.3_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:158619-159353:+ | gene-YJR024C_BG1 | rna-NM_001181682.3_BG1 | cds-NP_012558.3_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:467481-468215:- | gene-YJR024C_Bruggeman | rna-NM_001181682.3_Bruggeman | cds-NP_012558.3_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:471413-472147:- | gene-YJR024C_CAT1 | rna-NM_001181682.3_CAT1 | cds-NP_012558.3_CAT1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:465021-465755:- | gene-YJR024C_CBS1585 | rna-NM_001181682.3_CBS1585 | cds-NP_012558.3_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:483939-484673:- | gene-YJR024C_CBS436 | rna-NM_001181682.3_CBS436 | cds-NP_012558.3_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:453227-453961:- | gene-YJR024C_CBS6412 | rna-NM_001181682.3_CBS6412 | cds-NP_012558.3_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:455468-456202:- | gene-YJR024C_CBS6413 | rna-NM_001181682.3_CBS6413 | cds-NP_012558.3_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:452710-453444:- | gene-YJR024C_CENPK1137D | rna-NM_001181682.3_CENPK1137D | cds-NP_012558.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:458375-459109:- | gene-YJR024C_EthanolRed | rna-NM_001181682.3_EthanolRed | cds-NP_012558.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:469592-470326:- | gene-YJR024C_FaliES1 | rna-NM_001181682.3_FaliES1 | cds-NP_012558.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000030.1:81-815:- | gene-YJR024C_JAY291 | rna-NM_001181682.3_JAY291 | cds-NP_012558.3_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:467789-468523:- | gene-YJR024C_MUCL30387 | rna-NM_001181682.3_MUCL30387 | cds-NP_012558.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:464333-465067:- | gene-YJR024C_MUCL30388 | rna-NM_001181682.3_MUCL30388 | cds-NP_012558.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:458481-459215:- | gene-YJR024C_MUCL39482 | rna-NM_001181682.3_MUCL39482 | cds-NP_012558.3_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:463744-464478:- | gene-YJR024C_MUCL42920 | rna-NM_001181682.3_MUCL42920 | cds-NP_012558.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:470209-470943:- | gene-YJR024C_NCIM3186 | rna-NM_001181682.3_NCIM3186 | cds-NP_012558.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:456320-457054:- | gene-YJR024C_NCYC1407 | rna-NM_001181682.3_NCYC1407 | cds-NP_012558.3_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:474645-475379:- | gene-YJR024C_PE2H3 | rna-NM_001181682.3_PE2H3 | cds-NP_012558.3_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:468341-469075:- | gene-YJR024C_PE2H4 | rna-NM_001181682.3_PE2H4 | cds-NP_012558.3_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:470230-470964:- | gene-YJR024C_S288C | rna-NM_001181682.3_S288C | cds-NP_012558.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:266220-266954:- | gene-YJR024C_SA1 | rna-NM_001181682.3_SA1 | cds-NP_012558.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:463279-464013:- | gene-YJR024C_ThermosaccDry | rna-NM_001181682.3_ThermosaccDry | cds-NP_012558.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:465512-466246:- | gene-YJR024C_VR1 | rna-NM_001181682.3_VR1 | cds-NP_012558.3_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:443168-443902:- | gene-YJR024C_ZTW1 | rna-NM_001181682.3_ZTW1 | cds-NP_012558.3_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:467920-468654:- | gene-YJR024C_Sparadoxus | rna-NM_001181682.3_Sparadoxus | cds-NP_012558.3_Sparadoxus | 91.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |