Gene name: MCX1
Reference locus (S288C): YBR227C
Gene biotype: protein_coding
Description: ATP-dependent clpX-like chaperone, mitochondrial; Non-proteolytic ATPase of the AAA family; stimulates incorporation of the pyridoxal phosphate cofactor into Hem1p (5-aminolevulinic acid synthase); localized to the mitochondrial matrix; ortholog of vertebrate CLPX, which promotes erythropoiesis
Top 10 interactors (score): PIM1 (0.945); NFU1 (0.929); MGE1 (0.919); ACO1 (0.916); HSP78 (0.912); TIS11 (0.91); YME1 (0.909); HSP60 (0.887); MDJ1 (0.864); HSP104 (0.815); HEM25 (0.801); AFG3 (0.796); HEM1 (0.792); TOM20 (0.789); TIM44 (0.774); SSC1 (0.767); HSC82 (0.767); DFR1 (0.765); PHB1 (0.759); JAC1 (0.753)
Homologues (species, bitscore): CLPX (Homo sapiens, 294.3); Clpx (Mus musculus, 295.0); clpxb (Danio rerio, 280.0); clpx (Xenopus tropicalis, 294.7); CG4538 (Drosophila melanogaster, 262.3); K07A3.3 (Caenorhabditis elegans, 246.9); CLPX (Arabidopsis thaliana, 270.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:657881-659443:- | gene-YBR227C_AKU4011 | rna-NM_001178575.1_AKU4011 | cds-NP_009786.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:28800-30362:- | gene-YBR227C_BG1 | rna-NM_001178575.1_BG1 | cds-NP_009786.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:659034-660596:- | gene-YBR227C_Bruggeman | rna-NM_001178575.1_Bruggeman | cds-NP_009786.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:662239-663801:- | gene-YBR227C_CAT1 | rna-NM_001178575.1_CAT1 | cds-NP_009786.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:649413-650975:- | gene-YBR227C_CBS1585 | rna-NM_001178575.1_CBS1585 | cds-NP_009786.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:655836-657398:- | gene-YBR227C_CBS436 | rna-NM_001178575.1_CBS436 | cds-NP_009786.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:744390-745952:- | gene-YBR227C_CBS6412 | rna-NM_001178575.1_CBS6412 | cds-NP_009786.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:655451-657013:- | gene-YBR227C_CBS6413 | rna-NM_001178575.1_CBS6413 | cds-NP_009786.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:667352-668914:- | gene-YBR227C_CENPK1137D | rna-NM_001178575.1_CENPK1137D | cds-NP_009786.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:781122-782684:- | gene-YBR227C_EthanolRed | rna-NM_001178575.1_EthanolRed | cds-NP_009786.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:674229-675791:- | gene-YBR227C_FaliES1 | rna-NM_001178575.1_FaliES1 | cds-NP_009786.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000067.1:126562-128124:+ | gene-YBR227C_JAY291 | rna-NM_001178575.1_JAY291 | cds-NP_009786.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:661048-662610:- | gene-YBR227C_MUCL30387 | rna-NM_001178575.1_MUCL30387 | cds-NP_009786.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:678127-679689:- | gene-YBR227C_MUCL30388 | rna-NM_001178575.1_MUCL30388 | cds-NP_009786.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:647765-649327:- | gene-YBR227C_MUCL39482 | rna-NM_001178575.1_MUCL39482 | cds-NP_009786.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:657606-659168:- | gene-YBR227C_MUCL42920 | rna-NM_001178575.1_MUCL42920 | cds-NP_009786.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:673369-674931:- | gene-YBR227C_NCIM3186 | rna-NM_001178575.1_NCIM3186 | cds-NP_009786.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:649627-651189:- | gene-YBR227C_NCYC1407 | rna-NM_001178575.1_NCYC1407 | cds-NP_009786.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:672741-674303:- | gene-YBR227C_PE2H3 | rna-NM_001178575.1_PE2H3 | cds-NP_009786.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:670417-671979:- | gene-YBR227C_PE2H4 | rna-NM_001178575.1_PE2H4 | cds-NP_009786.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:673572-675134:- | gene-YBR227C_S288C | rna-NM_001178575.1_S288C | cds-NP_009786.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:28698-30260:- | gene-YBR227C_SA1 | rna-NM_001178575.1_SA1 | cds-NP_009786.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:673239-674801:- | gene-YBR227C_ThermosaccDry | rna-NM_001178575.1_ThermosaccDry | cds-NP_009786.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:653414-654976:- | gene-YBR227C_VR1 | rna-NM_001178575.1_VR1 | cds-NP_009786.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:646105-647667:- | gene-YBR227C_ZTW1 | rna-NM_001178575.1_ZTW1 | cds-NP_009786.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:690077-691639:- | gene-YBR227C_Sparadoxus | rna-NM_001178575.1_Sparadoxus | cds-NP_009786.1_Sparadoxus | 89.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |