Gene name: MCP2
Reference locus (S288C): YLR253W
Gene biotype: protein_coding
Description: ABC1 family protein MCP2; Mitochondrial protein of unknown function involved in lipid homeostasis; associates with mitochondrial ribosome; integral membrane protein that localizes to the mitochondrial inner membrane; involved in mitochondrial morphology; non-essential gene which interacts genetically with MDM10, and other members of the ERMES complex; transcription is periodic during the metabolic cycle; homologous to human aarF domain containing kinase, ADCK1
Top 10 interactors (score): MCP1 (0.909); MDM12 (0.83); COQ3 (0.809); MDM10 (0.802); COQ6 (0.785); VPS13 (0.772); MDM34 (0.763); MIC60 (0.761); SCY1 (0.749); IKS1 (0.714); CAT5 (0.701); YME1 (0.699); FMP48 (0.686); KKQ8 (0.679); YPL150W (0.672); OCT1 (0.668); RIO2 (0.665); RIO1 (0.656); OMA1 (0.654); ISR1 (0.654)
Homologues (species, bitscore): ADCK1 (Homo sapiens, 256.1); Adck1 (Mus musculus, 254.6); adck1 (Danio rerio, 271.6); adck1 (Xenopus tropicalis, 241.1); CG3608 (Drosophila melanogaster, 251.5); D2023.6 (Caenorhabditis elegans, 243.8); ATH9 (Arabidopsis thaliana, 231.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:596838-598547:+ | gene-YLR253W_AKU4011 | rna-NM_001182140.1_AKU4011 | cds-NP_013354.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:133350-135059:- | gene-YLR253W_BG1 | rna-NM_001182140.1_BG1 | cds-NP_013354.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:631072-632781:+ | gene-YLR253W_Bruggeman | rna-NM_001182140.1_Bruggeman | cds-NP_013354.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:630201-631910:+ | gene-YLR253W_CAT1 | rna-NM_001182140.1_CAT1 | cds-NP_013354.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:632333-634042:+ | gene-YLR253W_CBS1585 | rna-NM_001182140.1_CBS1585 | cds-NP_013354.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:616538-618247:+ | gene-YLR253W_CBS436 | rna-NM_001182140.1_CBS436 | cds-NP_013354.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:595308-597017:+ | gene-YLR253W_CBS6412 | rna-NM_001182140.1_CBS6412 | cds-NP_013354.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:632628-634337:+ | gene-YLR253W_CBS6413 | rna-NM_001182140.1_CBS6413 | cds-NP_013354.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:627268-628977:+ | gene-YLR253W_CENPK1137D | rna-NM_001182140.1_CENPK1137D | cds-NP_013354.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:590951-592660:+ | gene-YLR253W_EthanolRed | rna-NM_001182140.1_EthanolRed | cds-NP_013354.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:619788-621497:+ | gene-YLR253W_FaliES1 | rna-NM_001182140.1_FaliES1 | cds-NP_013354.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000136.1:37874-39583:- | gene-YLR253W_JAY291 | rna-NM_001182140.1_JAY291 | cds-NP_013354.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:631930-633639:+ | gene-YLR253W_MUCL30387 | rna-NM_001182140.1_MUCL30387 | cds-NP_013354.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:636056-637765:+ | gene-YLR253W_MUCL30388 | rna-NM_001182140.1_MUCL30388 | cds-NP_013354.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:633314-635023:+ | gene-YLR253W_MUCL39482 | rna-NM_001182140.1_MUCL39482 | cds-NP_013354.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:628072-629781:+ | gene-YLR253W_MUCL42920 | rna-NM_001182140.1_MUCL42920 | cds-NP_013354.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:642601-644310:+ | gene-YLR253W_NCIM3186 | rna-NM_001182140.1_NCIM3186 | cds-NP_013354.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:620300-622009:+ | gene-YLR253W_NCYC1407 | rna-NM_001182140.1_NCYC1407 | cds-NP_013354.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:624026-625735:+ | gene-YLR253W_PE2H3 | rna-NM_001182140.1_PE2H3 | cds-NP_013354.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:623770-625479:+ | gene-YLR253W_PE2H4 | rna-NM_001182140.1_PE2H4 | cds-NP_013354.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:642627-644336:+ | gene-YLR253W_S288C | rna-NM_001182140.1_S288C | cds-NP_013354.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:38128-39837:- | gene-YLR253W_SA1 | rna-NM_001182140.1_SA1 | cds-NP_013354.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:621796-623505:+ | gene-YLR253W_ThermosaccDry | rna-NM_001182140.1_ThermosaccDry | cds-NP_013354.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:633143-634852:+ | gene-YLR253W_VR1 | rna-NM_001182140.1_VR1 | cds-NP_013354.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000024.1:146112-147821:+ | gene-YLR253W_ZTW1 | rna-NM_001182140.1_ZTW1 | cds-NP_013354.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:607916-609625:+ | gene-YLR253W_Sparadoxus | rna-NM_001182140.1_Sparadoxus | cds-NP_013354.1_Sparadoxus | 90.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |