Gene name: MCM5
Reference locus (S288C): YLR274W
Gene biotype: protein_coding
Description: Minichromosome maintenance protein 5; Component of the Mcm2-7 hexameric helicase complex; MCM complex is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
Top 10 interactors (score): CDC7 (0.999); MCM3 (0.999); TOF1 (0.999); PSF1 (0.999); ORC5 (0.999); CDC6 (0.999); MCM4 (0.999); SLD5 (0.999); ORC1 (0.999); ORC4 (0.999); ORC2 (0.999); MCM10 (0.999); CTF4 (0.999); CSM3 (0.999); PSF3 (0.999); MCM7 (0.999); MCM2 (0.999); MCM6 (0.999); CDC45 (0.999); POL2 (0.999)
Homologues (species, bitscore): MCM5 (Homo sapiens, 679.1); Mcm5 (Mus musculus, 668.7); mcm5 (Danio rerio, 671.0); mcm5 (Xenopus tropicalis, 687.6); Mcm5 (Drosophila melanogaster, 664.8); mcm-5 (Caenorhabditis elegans, 632.5); MCM5 (Arabidopsis thaliana, 629.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:640414-642741:+ | gene-YLR274W_AKU4011 | rna-NM_001182161.1_AKU4011 | cds-NP_013376.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:89941-92268:- | gene-YLR274W_BG1 | rna-NM_001182161.1_BG1 | cds-NP_013376.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:675355-677682:+ | gene-YLR274W_Bruggeman | rna-NM_001182161.1_Bruggeman | cds-NP_013376.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:674179-676506:+ | gene-YLR274W_CAT1 | rna-NM_001182161.1_CAT1 | cds-NP_013376.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:675313-677640:+ | gene-YLR274W_CBS1585 | rna-NM_001182161.1_CBS1585 | cds-NP_013376.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:659941-662268:+ | gene-YLR274W_CBS436 | rna-NM_001182161.1_CBS436 | cds-NP_013376.1_CBS436 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:637947-640274:+ | gene-YLR274W_CBS6412 | rna-NM_001182161.1_CBS6412 | cds-NP_013376.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:675955-678282:+ | gene-YLR274W_CBS6413 | rna-NM_001182161.1_CBS6413 | cds-NP_013376.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:676187-678514:+ | gene-YLR274W_CENPK1137D | rna-NM_001182161.1_CENPK1137D | cds-NP_013376.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:633874-636201:+ | gene-YLR274W_EthanolRed | rna-NM_001182161.1_EthanolRed | cds-NP_013376.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:662863-665190:+ | gene-YLR274W_FaliES1 | rna-NM_001182161.1_FaliES1 | cds-NP_013376.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000359.1:40558-42885:- | gene-YLR274W_JAY291 | rna-NM_001182161.1_JAY291 | cds-NP_013376.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:675484-677811:+ | gene-YLR274W_MUCL30387 | rna-NM_001182161.1_MUCL30387 | cds-NP_013376.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:680841-683168:+ | gene-YLR274W_MUCL30388 | rna-NM_001182161.1_MUCL30388 | cds-NP_013376.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:676540-678867:+ | gene-YLR274W_MUCL39482 | rna-NM_001182161.1_MUCL39482 | cds-NP_013376.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:671740-674067:+ | gene-YLR274W_MUCL42920 | rna-NM_001182161.1_MUCL42920 | cds-NP_013376.1_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:691529-693856:+ | gene-YLR274W_NCIM3186 | rna-NM_001182161.1_NCIM3186 | cds-NP_013376.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:663798-666125:+ | gene-YLR274W_NCYC1407 | rna-NM_001182161.1_NCYC1407 | cds-NP_013376.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:673699-676026:+ | gene-YLR274W_PE2H3 | rna-NM_001182161.1_PE2H3 | cds-NP_013376.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:673443-675770:+ | gene-YLR274W_PE2H4 | rna-NM_001182161.1_PE2H4 | cds-NP_013376.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:691555-693882:+ | gene-YLR274W_S288C | rna-NM_001182161.1_S288C | cds-NP_013376.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000039.1:90747-93074:- | gene-YLR274W_SA1 | rna-NM_001182161.1_SA1 | cds-NP_013376.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:664806-667133:+ | gene-YLR274W_ThermosaccDry | rna-NM_001182161.1_ThermosaccDry | cds-NP_013376.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:676733-679060:+ | gene-YLR274W_VR1 | rna-NM_001182161.1_VR1 | cds-NP_013376.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:3169-5496:+ | gene-YLR274W_ZTW1 | rna-NM_001182161.1_ZTW1 | cds-NP_013376.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:650866-653193:+ | gene-YLR274W_Sparadoxus | rna-NM_001182161.1_Sparadoxus | cds-NP_013376.1_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |