MCM22 (YJR135C)


Gene profile

Gene name: MCM22
Reference locus (S288C): YJR135C
Gene biotype: protein_coding

Description: Central kinetochore subunit MCM22; Outer kinetochore protein and component of the Ctf3 subcomplex; binds to centromeric DNA in a Ctf19p-dependent manner; involved in chromosome segregation and minichromosome maintenance; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-K and fission yeast sim4

Top 10 interactors (score): MCM16 (0.999); CTF3 (0.998); IML3 (0.996); CTF19 (0.995); OKP1 (0.995); CHL4 (0.992); NKP1 (0.989); MCM21 (0.988); AME1 (0.987); NKP2 (0.982); CNN1 (0.98); DSN1 (0.97); CSE4 (0.964); WIP1 (0.961); HHF1 (0.917); HTA1 (0.839); BIM1 (0.838); CHL1 (0.835); MIF2 (0.824); HTA2 (0.821)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:647557-648276:- gene-YJR135C_AKU4011 rna-NM_001181793.1_AKU4011 cds-NP_012669.1_AKU4011 99.8 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000076.1:25324-26043:+ gene-YJR135C_BG1 rna-NM_001181793.1_BG1 cds-NP_012669.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:663287-664006:- gene-YJR135C_Bruggeman rna-NM_001181793.1_Bruggeman cds-NP_012669.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:667926-668645:- gene-YJR135C_CAT1 rna-NM_001181793.1_CAT1 cds-NP_012669.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:659601-660320:- gene-YJR135C_CBS1585 rna-NM_001181793.1_CBS1585 cds-NP_012669.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:678473-679192:- gene-YJR135C_CBS436 rna-NM_001181793.1_CBS436 cds-NP_012669.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:646378-647097:- gene-YJR135C_CBS6412 rna-NM_001181793.1_CBS6412 cds-NP_012669.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:649035-649754:- gene-YJR135C_CBS6413 rna-NM_001181793.1_CBS6413 cds-NP_012669.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:658419-659138:- gene-YJR135C_CENPK1137D rna-NM_001181793.1_CENPK1137D cds-NP_012669.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:651978-652697:- gene-YJR135C_EthanolRed rna-NM_001181793.1_EthanolRed cds-NP_012669.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:663441-664160:- gene-YJR135C_FaliES1 rna-NM_001181793.1_FaliES1 cds-NP_012669.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000054.1:24997-25716:+ gene-YJR135C_JAY291 rna-NM_001181793.1_JAY291 cds-NP_012669.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:662318-663037:- gene-YJR135C_MUCL30387 rna-NM_001181793.1_MUCL30387 cds-NP_012669.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:659802-660521:- gene-YJR135C_MUCL30388 rna-NM_001181793.1_MUCL30388 cds-NP_012669.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:653086-653805:- gene-YJR135C_MUCL39482 rna-NM_001181793.1_MUCL39482 cds-NP_012669.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:657823-658542:- gene-YJR135C_MUCL42920 rna-NM_001181793.1_MUCL42920 cds-NP_012669.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:676038-676757:- gene-YJR135C_NCIM3186 rna-NM_001181793.1_NCIM3186 cds-NP_012669.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:650635-651354:- gene-YJR135C_NCYC1407 rna-NM_001181793.1_NCYC1407 cds-NP_012669.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:668825-669544:- gene-YJR135C_PE2H3 rna-NM_001181793.1_PE2H3 cds-NP_012669.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:662514-663233:- gene-YJR135C_PE2H4 rna-NM_001181793.1_PE2H4 cds-NP_012669.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:676059-676778:- gene-YJR135C_S288C rna-NM_001181793.1_S288C cds-NP_012669.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000069.1:25349-26068:+ gene-YJR135C_SA1 rna-NM_001181793.1_SA1 cds-NP_012669.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:657372-658091:- gene-YJR135C_ThermosaccDry rna-NM_001181793.1_ThermosaccDry cds-NP_012669.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:659745-660464:- gene-YJR135C_VR1 rna-NM_001181793.1_VR1 cds-NP_012669.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:636721-637440:- gene-YJR135C_ZTW1 rna-NM_001181793.1_ZTW1 cds-NP_012669.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:671010-671729:- gene-YJR135C_Sparadoxus rna-NM_001181793.1_Sparadoxus cds-NP_012669.1_Sparadoxus 85.6 100.0 Verified 1 1 1 False True False False False

Additional files