Gene name: MCM21
Reference locus (S288C): YDR318W
Gene biotype: protein_coding
Description: Central kinetochore subunit MCM21; Component of the kinetochore sub-complex COMA; COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) bridges kinetochore subunits in contact with centromeric DNA with subunits bound to microtubules during kinetochore assembly; involved in minichromosome maintenance; modified by sumoylation; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-O and fission yeast mal2
Top 10 interactors (score): OKP1 (0.999); CTF19 (0.999); AME1 (0.999); IML3 (0.997); MCM16 (0.995); CTF3 (0.994); NKP2 (0.989); MCM22 (0.988); CSE4 (0.988); CHL4 (0.986); DSN1 (0.972); NKP1 (0.967); MIF2 (0.925); HHF1 (0.92); MTW1 (0.918); NNF1 (0.904); SPC24 (0.899); MAD2 (0.879); CHL1 (0.85); BIM1 (0.843)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:1049800-1050989:+ | gene-YDR318W_AKU4011 | rna-NM_001180626.3_AKU4011 | cds-NP_010604.4_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:80554-81743:- | gene-YDR318W_BG1 | rna-NM_001180626.3_BG1 | cds-NP_010604.4_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:1077330-1078519:+ | gene-YDR318W_Bruggeman | rna-NM_001180626.3_Bruggeman | cds-NP_010604.4_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:1064088-1065277:+ | gene-YDR318W_CAT1 | rna-NM_001180626.3_CAT1 | cds-NP_010604.4_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:1044244-1045433:+ | gene-YDR318W_CBS1585 | rna-NM_001180626.3_CBS1585 | cds-NP_010604.4_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:1062629-1063818:+ | gene-YDR318W_CBS436 | rna-NM_001180626.3_CBS436 | cds-NP_010604.4_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:1040931-1042120:+ | gene-YDR318W_CBS6412 | rna-NM_001180626.3_CBS6412 | cds-NP_010604.4_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:1062164-1063353:+ | gene-YDR318W_CBS6413 | rna-NM_001180626.3_CBS6413 | cds-NP_010604.4_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:1102402-1103591:+ | gene-YDR318W_CENPK1137D | rna-NM_001180626.3_CENPK1137D | cds-NP_010604.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:225341-226530:+ | gene-YDR318W_EthanolRed | rna-NM_001180626.3_EthanolRed | cds-NP_010604.4_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:1056556-1057745:+ | gene-YDR318W_FaliES1 | rna-NM_001180626.3_FaliES1 | cds-NP_010604.4_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000386.1:9070-10259:+ | gene-YDR318W_JAY291 | rna-NM_001180626.3_JAY291 | cds-NP_010604.4_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:1062592-1063781:+ | gene-YDR318W_MUCL30387 | rna-NM_001180626.3_MUCL30387 | cds-NP_010604.4_MUCL30387 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:1051526-1052715:+ | gene-YDR318W_MUCL30388 | rna-NM_001180626.3_MUCL30388 | cds-NP_010604.4_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:1036051-1037240:+ | gene-YDR318W_MUCL39482 | rna-NM_001180626.3_MUCL39482 | cds-NP_010604.4_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:983141-984330:+ | gene-YDR318W_MUCL42920 | rna-NM_001180626.3_MUCL42920 | cds-NP_010604.4_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:1103798-1104870:+ | gene-YDR318W_NCIM3186 | rna-NM_001180626.3_NCIM3186 | cds-NP_010604.4_NCIM3186 | 95.4 | 96.2 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:1049343-1050532:+ | gene-YDR318W_NCYC1407 | rna-NM_001180626.3_NCYC1407 | cds-NP_010604.4_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:1060346-1061535:+ | gene-YDR318W_PE2H3 | rna-NM_001180626.3_PE2H3 | cds-NP_010604.4_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:1065931-1067120:+ | gene-YDR318W_PE2H4 | rna-NM_001180626.3_PE2H4 | cds-NP_010604.4_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:1103758-1104947:+ | gene-YDR318W_S288C | rna-NM_001180626.3_S288C | cds-NP_010604.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000025.1:74577-75766:+ | gene-YDR318W_SA1 | rna-NM_001180626.3_SA1 | cds-NP_010604.4_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:1060829-1062018:+ | gene-YDR318W_ThermosaccDry | rna-NM_001180626.3_ThermosaccDry | cds-NP_010604.4_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:1076761-1077950:+ | gene-YDR318W_VR1 | rna-NM_001180626.3_VR1 | cds-NP_010604.4_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000008.1:104944-106133:+ | gene-YDR318W_ZTW1 | rna-NM_001180626.3_ZTW1 | cds-NP_010604.4_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:1056306-1057498:+ | gene-YDR318W_Sparadoxus | rna-NM_001180626.3_Sparadoxus | cds-NP_010604.4_Sparadoxus | 88.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |