MCM2 (YBL023C)


Gene profile

Gene name: MCM2
Reference locus (S288C): YBL023C
Gene biotype: protein_coding

Description: Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex; relative distribution to the nucleus increases upon DNA replication stress

Top 10 interactors (score): SLD5 (0.999); PSF1 (0.999); TOF1 (0.999); RFA1 (0.999); MCM5 (0.999); MCM3 (0.999); ORC6 (0.999); ORC1 (0.999); POL1 (0.999); PSF2 (0.999); MCM6 (0.999); ORC2 (0.999); CDC45 (0.999); MCM7 (0.999); DBF4 (0.999); MCM4 (0.999); ASF1 (0.999); ORC4 (0.999); ORC5 (0.999); CDC6 (0.999)

Homologues (species, bitscore): MCM2 (Homo sapiens, 785.4); Mcm2 (Mus musculus, 781.6); mcm2 (Danio rerio, 783.5); mcm2 (Xenopus tropicalis, 787.7); Mcm2 (Drosophila melanogaster, 752.7); mcm-2 (Caenorhabditis elegans, 699.9); MCM2 (Arabidopsis thaliana, 754.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:168530-171136:- gene-YBL023C_AKU4011 rna-NM_001178263.1_AKU4011 cds-NP_009530.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:159358-161964:- gene-YBL023C_BG1 rna-NM_001178263.1_BG1 cds-NP_009530.1_BG1 99.5 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:169116-171722:- gene-YBL023C_Bruggeman rna-NM_001178263.1_Bruggeman cds-NP_009530.1_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005520.1:171727-174333:- gene-YBL023C_CAT1 rna-NM_001178263.1_CAT1 cds-NP_009530.1_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:161085-163691:- gene-YBL023C_CBS1585 rna-NM_001178263.1_CBS1585 cds-NP_009530.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:169540-172146:- gene-YBL023C_CBS436 rna-NM_001178263.1_CBS436 cds-NP_009530.1_CBS436 99.5 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:259864-262470:- gene-YBL023C_CBS6412 rna-NM_001178263.1_CBS6412 cds-NP_009530.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:166655-169261:- gene-YBL023C_CBS6413 rna-NM_001178263.1_CBS6413 cds-NP_009530.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:168685-171291:- gene-YBL023C_CENPK1137D rna-NM_001178263.1_CENPK1137D cds-NP_009530.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:296072-298678:- gene-YBL023C_EthanolRed rna-NM_001178263.1_EthanolRed cds-NP_009530.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:183338-185944:- gene-YBL023C_FaliES1 rna-NM_001178263.1_FaliES1 cds-NP_009530.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000421.1:9009-11615:- gene-YBL023C_JAY291 rna-NM_001178263.1_JAY291 cds-NP_009530.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:168973-171579:- gene-YBL023C_MUCL30387 rna-NM_001178263.1_MUCL30387 cds-NP_009530.1_MUCL30387 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:170015-172621:- gene-YBL023C_MUCL30388 rna-NM_001178263.1_MUCL30388 cds-NP_009530.1_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:161270-163876:- gene-YBL023C_MUCL39482 rna-NM_001178263.1_MUCL39482 cds-NP_009530.1_MUCL39482 99.9 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:168545-171151:- gene-YBL023C_MUCL42920 rna-NM_001178263.1_MUCL42920 cds-NP_009530.1_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:174717-177323:- gene-YBL023C_NCIM3186 rna-NM_001178263.1_NCIM3186 cds-NP_009530.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:162419-165025:- gene-YBL023C_NCYC1407 rna-NM_001178263.1_NCYC1407 cds-NP_009530.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:168646-171252:- gene-YBL023C_PE2H3 rna-NM_001178263.1_PE2H3 cds-NP_009530.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:166290-168896:- gene-YBL023C_PE2H4 rna-NM_001178263.1_PE2H4 cds-NP_009530.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:174920-177526:- gene-YBL023C_S288C rna-NM_001178263.1_S288C cds-NP_009530.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000051.1:59641-62247:- gene-YBL023C_SA1 rna-NM_001178263.1_SA1 cds-NP_009530.1_SA1 99.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:183293-185899:- gene-YBL023C_ThermosaccDry rna-NM_001178263.1_ThermosaccDry cds-NP_009530.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:165459-168065:- gene-YBL023C_VR1 rna-NM_001178263.1_VR1 cds-NP_009530.1_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:160005-162611:- gene-YBL023C_ZTW1 rna-NM_001178263.1_ZTW1 cds-NP_009530.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:194961-197567:- gene-YBL023C_Sparadoxus rna-NM_001178263.1_Sparadoxus cds-NP_009530.1_Sparadoxus 91.6 100.0 Verified 1 1 1 False True False False False

Additional files