MCD4 (YKL165C)


Gene profile

Gene name: MCD4
Reference locus (S288C): YKL165C
Gene biotype: protein_coding

Description: Mannose-ethanolamine phosphotransferase mcd4; GPI ethanolamine phosphate transferase 1; Protein involved in GPI anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes; GPI stands for glycosylphosphatidylinositol

Top 10 interactors (score): GPI10 (0.998); GPI18 (0.989); GWT1 (0.966); GPI11 (0.961); SPT14 (0.908); GPI12 (0.872); GPI1 (0.852); CWH43 (0.805); PER1 (0.79); CDC1 (0.785); SMP3 (0.781); GPI16 (0.77); GPI14 (0.763); MAN2 (0.745); YJR011C (0.745); TRP3 (0.733); MSC2 (0.708); BST1 (0.691); SKI6 (0.689); DCW1 (0.688)

Homologues (species, bitscore): PIGN (Homo sapiens, 578.9); Pign (Mus musculus, 568.9); pign (Danio rerio, 567.0); PIGN (Xenopus tropicalis, 547.7); CG2292 (Drosophila melanogaster, 365.2); pign-1 (Caenorhabditis elegans, 367.9); AT3G01380 (Arabidopsis thaliana, 545.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:124785-127544:- gene-YKL165C_AKU4011 rna-NM_001179731.1_AKU4011 cds-NP_012756.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:101340-104099:- gene-YKL165C_BG1 rna-NM_001179731.1_BG1 cds-NP_012756.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:142179-144938:- gene-YKL165C_Bruggeman rna-NM_001179731.1_Bruggeman cds-NP_012756.1_Bruggeman 99.8 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:137133-139892:- gene-YKL165C_CAT1 rna-NM_001179731.1_CAT1 cds-NP_012756.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:136769-139528:- gene-YKL165C_CBS1585 rna-NM_001179731.1_CBS1585 cds-NP_012756.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:135529-138288:- gene-YKL165C_CBS436 rna-NM_001179731.1_CBS436 cds-NP_012756.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:122363-125122:- gene-YKL165C_CBS6412 rna-NM_001179731.1_CBS6412 cds-NP_012756.1_CBS6412 99.6 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:137485-140244:- gene-YKL165C_CBS6413 rna-NM_001179731.1_CBS6413 cds-NP_012756.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:137742-140501:- gene-YKL165C_CENPK1137D rna-NM_001179731.1_CENPK1137D cds-NP_012756.1_CENPK1137D 99.9 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:135682-138441:- gene-YKL165C_EthanolRed rna-NM_001179731.1_EthanolRed cds-NP_012756.1_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:136383-139142:- gene-YKL165C_FaliES1 rna-NM_001179731.1_FaliES1 cds-NP_012756.1_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:135351-138110:- gene-YKL165C_JAY291 rna-NM_001179731.1_JAY291 cds-NP_012756.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:144470-147229:- gene-YKL165C_MUCL30387 rna-NM_001179731.1_MUCL30387 cds-NP_012756.1_MUCL30387 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:138823-141582:- gene-YKL165C_MUCL30388 rna-NM_001179731.1_MUCL30388 cds-NP_012756.1_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:136824-139583:- gene-YKL165C_MUCL39482 rna-NM_001179731.1_MUCL39482 cds-NP_012756.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:141155-143914:- gene-YKL165C_MUCL42920 rna-NM_001179731.1_MUCL42920 cds-NP_012756.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:137921-140680:- gene-YKL165C_NCIM3186 rna-NM_001179731.1_NCIM3186 cds-NP_012756.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:136848-139607:- gene-YKL165C_NCYC1407 rna-NM_001179731.1_NCYC1407 cds-NP_012756.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:143906-146665:- gene-YKL165C_PE2H3 rna-NM_001179731.1_PE2H3 cds-NP_012756.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:140200-142959:- gene-YKL165C_PE2H4 rna-NM_001179731.1_PE2H4 cds-NP_012756.1_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:137932-140691:- gene-YKL165C_S288C rna-NM_001179731.1_S288C cds-NP_012756.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000008.1:54130-56889:- gene-YKL165C_SA1 rna-NM_001179731.1_SA1 cds-NP_012756.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:137083-139842:- gene-YKL165C_ThermosaccDry rna-NM_001179731.1_ThermosaccDry cds-NP_012756.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:135609-138368:- gene-YKL165C_VR1 rna-NM_001179731.1_VR1 cds-NP_012756.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:135821-138580:- gene-YKL165C_ZTW1 rna-NM_001179731.1_ZTW1 cds-NP_012756.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:150119-152878:- gene-YKL165C_Sparadoxus rna-NM_001179731.1_Sparadoxus cds-NP_012756.1_Sparadoxus 90.4 100.0 Verified 1 1 1 False True False False False

Additional files