Gene name: MCD1
Reference locus (S288C): YDL003W
Gene biotype: protein_coding
Description: Sister chromatid cohesion protein 1; Essential alpha-kleisin subunit of the cohesin complex; required for sister chromatid cohesion in mitosis and meiosis; apoptosis induces cleavage and translocation of a C-terminal fragment to mitochondria; expression peaks in S phase
Top 10 interactors (score): SMC3 (0.999); SCC2 (0.999); SMC5 (0.999); IRR1 (0.999); PDS5 (0.999); ESP1 (0.999); SMC1 (0.999); ECO1 (0.999); CDC5 (0.999); SMC2 (0.994); SMC6 (0.993); SMC4 (0.986); RAD61 (0.977); YCG1 (0.954); CTF4 (0.954); SCC4 (0.953); CTF18 (0.952); PDS1 (0.947); POL1 (0.947); POL12 (0.946)
Homologues (species, bitscore): RAD21 (Homo sapiens, 61.2); Rad21 (Mus musculus, 61.6); rad21l1 (Danio rerio, 62.4); rad21 (Xenopus tropicalis, 61.6); vtd (Drosophila melanogaster, 67.8); coh-1 (Caenorhabditis elegans, 66.6); SYN4 (Arabidopsis thaliana, 53.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:429933-431633:+ | gene-YDL003W_AKU4011 | rna-NM_001180062.1_AKU4011 | cds-NP_010281.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:117743-119443:- | gene-YDL003W_BG1 | rna-NM_001180062.1_BG1 | cds-NP_010281.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:450534-452234:+ | gene-YDL003W_Bruggeman | rna-NM_001180062.1_Bruggeman | cds-NP_010281.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:443381-445081:+ | gene-YDL003W_CAT1 | rna-NM_001180062.1_CAT1 | cds-NP_010281.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:427144-428844:+ | gene-YDL003W_CBS1585 | rna-NM_001180062.1_CBS1585 | cds-NP_010281.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:443909-445609:+ | gene-YDL003W_CBS436 | rna-NM_001180062.1_CBS436 | cds-NP_010281.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:424392-426092:+ | gene-YDL003W_CBS6412 | rna-NM_001180062.1_CBS6412 | cds-NP_010281.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:446082-447782:+ | gene-YDL003W_CBS6413 | rna-NM_001180062.1_CBS6413 | cds-NP_010281.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:443546-445246:+ | gene-YDL003W_CENPK1137D | rna-NM_001180062.1_CENPK1137D | cds-NP_010281.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:438765-440465:+ | gene-YDL003W_EthanolRed | rna-NM_001180062.1_EthanolRed | cds-NP_010281.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:444936-446636:+ | gene-YDL003W_FaliES1 | rna-NM_001180062.1_FaliES1 | cds-NP_010281.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000442.1:25425-27125:- | gene-YDL003W_JAY291 | rna-NM_001180062.1_JAY291 | cds-NP_010281.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:444405-446105:+ | gene-YDL003W_MUCL30387 | rna-NM_001180062.1_MUCL30387 | cds-NP_010281.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:434867-436567:+ | gene-YDL003W_MUCL30388 | rna-NM_001180062.1_MUCL30388 | cds-NP_010281.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:428513-430213:+ | gene-YDL003W_MUCL39482 | rna-NM_001180062.1_MUCL39482 | cds-NP_010281.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:349940-351640:+ | gene-YDL003W_MUCL42920 | rna-NM_001180062.1_MUCL42920 | cds-NP_010281.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:444606-446306:+ | gene-YDL003W_NCIM3186 | rna-NM_001180062.1_NCIM3186 | cds-NP_010281.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:427435-429135:+ | gene-YDL003W_NCYC1407 | rna-NM_001180062.1_NCYC1407 | cds-NP_010281.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:443038-444738:+ | gene-YDL003W_PE2H3 | rna-NM_001180062.1_PE2H3 | cds-NP_010281.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:442351-444051:+ | gene-YDL003W_PE2H4 | rna-NM_001180062.1_PE2H4 | cds-NP_010281.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:444683-446383:+ | gene-YDL003W_S288C | rna-NM_001180062.1_S288C | cds-NP_010281.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000099.1:25614-27314:- | gene-YDL003W_SA1 | rna-NM_001180062.1_SA1 | cds-NP_010281.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:444415-446115:+ | gene-YDL003W_ThermosaccDry | rna-NM_001180062.1_ThermosaccDry | cds-NP_010281.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:448849-450549:+ | gene-YDL003W_VR1 | rna-NM_001180062.1_VR1 | cds-NP_010281.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:442311-444011:+ | gene-YDL003W_ZTW1 | rna-NM_001180062.1_ZTW1 | cds-NP_010281.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:446655-448349:+ | gene-YDL003W_Sparadoxus | rna-NM_001180062.1_Sparadoxus | cds-NP_010281.1_Sparadoxus | 86.7 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |