Gene name: MBF1
Reference locus (S288C): YOR298C-A
Gene biotype: protein_coding
Description: Multiprotein-bridging factor 1; Transcriptional coactivator; bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations; protein abundance increases in response to DNA replication stress; Belongs to the MBF1 family
Top 10 interactors (score): SPT15 (0.99); AHA1 (0.973); SUA7 (0.966); DST1 (0.963); HCH1 (0.958); FES1 (0.952); SIS1 (0.945); CPR6 (0.94); HSP82 (0.936); HSP104 (0.934); HSP78 (0.934); STI1 (0.933); HSC82 (0.926); TPS1 (0.908); SIL1 (0.9); SHP1 (0.896); SBA1 (0.896); HSP26 (0.896); GCN4 (0.888); ASC1 (0.86)
Homologues (species, bitscore): EDF1 (Homo sapiens, 122.1); Edf1 (Mus musculus, 124.0); edf1 (Danio rerio, 118.2); edf1 (Xenopus tropicalis, 122.5); mbf1 (Drosophila melanogaster, 126.7); mbf-1 (Caenorhabditis elegans, 116.3); MBF1B (Arabidopsis thaliana, 97.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:867690-868145:- | gene-YOR298C-A_AKU4011 | rna-NM_001184346.3_AKU4011 | cds-NP_014942.4_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:269734-270189:- | gene-YOR298C-A_BG1 | rna-NM_001184346.3_BG1 | cds-NP_014942.4_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:853135-853590:- | gene-YOR298C-A_Bruggeman | rna-NM_001184346.3_Bruggeman | cds-NP_014942.4_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:853864-854319:- | gene-YOR298C-A_CAT1 | rna-NM_001184346.3_CAT1 | cds-NP_014942.4_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:851524-851979:- | gene-YOR298C-A_CBS1585 | rna-NM_001184346.3_CBS1585 | cds-NP_014942.4_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:849365-849820:- | gene-YOR298C-A_CBS436 | rna-NM_001184346.3_CBS436 | cds-NP_014942.4_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:847222-847677:- | gene-YOR298C-A_CBS6412 | rna-NM_001184346.3_CBS6412 | cds-NP_014942.4_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:856417-856872:- | gene-YOR298C-A_CBS6413 | rna-NM_001184346.3_CBS6413 | cds-NP_014942.4_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:877013-877468:- | gene-YOR298C-A_CENPK1137D | rna-NM_001184346.3_CENPK1137D | cds-NP_014942.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:843604-844059:- | gene-YOR298C-A_EthanolRed | rna-NM_001184346.3_EthanolRed | cds-NP_014942.4_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:849222-849677:- | gene-YOR298C-A_FaliES1 | rna-NM_001184346.3_FaliES1 | cds-NP_014942.4_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:153562-154017:+ | gene-YOR298C-A_JAY291 | rna-NM_001184346.3_JAY291 | cds-NP_014942.4_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:857385-857840:- | gene-YOR298C-A_MUCL30387 | rna-NM_001184346.3_MUCL30387 | cds-NP_014942.4_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:865361-865816:- | gene-YOR298C-A_MUCL30388 | rna-NM_001184346.3_MUCL30388 | cds-NP_014942.4_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:858052-858507:- | gene-YOR298C-A_MUCL39482 | rna-NM_001184346.3_MUCL39482 | cds-NP_014942.4_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:867551-868006:- | gene-YOR298C-A_MUCL42920 | rna-NM_001184346.3_MUCL42920 | cds-NP_014942.4_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:877119-877574:- | gene-YOR298C-A_NCIM3186 | rna-NM_001184346.3_NCIM3186 | cds-NP_014942.4_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:859064-859519:- | gene-YOR298C-A_NCYC1407 | rna-NM_001184346.3_NCYC1407 | cds-NP_014942.4_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:857298-857753:- | gene-YOR298C-A_PE2H3 | rna-NM_001184346.3_PE2H3 | cds-NP_014942.4_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:873650-874105:- | gene-YOR298C-A_PE2H4 | rna-NM_001184346.3_PE2H4 | cds-NP_014942.4_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:877230-877685:- | gene-YOR298C-A_S288C | rna-NM_001184346.3_S288C | cds-NP_014942.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:286931-287386:- | gene-YOR298C-A_SA1 | rna-NM_001184346.3_SA1 | cds-NP_014942.4_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:848405-848860:- | gene-YOR298C-A_ThermosaccDry | rna-NM_001184346.3_ThermosaccDry | cds-NP_014942.4_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:911740-912195:- | gene-YOR298C-A_VR1 | rna-NM_001184346.3_VR1 | cds-NP_014942.4_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:581291-581746:- | gene-YOR298C-A_ZTW1 | rna-NM_001184346.3_ZTW1 | cds-NP_014942.4_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:855461-855916:- | gene-YOR298C-A_Sparadoxus | rna-NM_001184346.3_Sparadoxus | cds-NP_014942.4_Sparadoxus | 92.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |