MAK5 (YBR142W)


Gene profile

Gene name: MAK5
Reference locus (S288C): YBR142W
Gene biotype: protein_coding

Description: Essential nucleolar protein; putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus; involved in biogenesis of large (60S) ribosomal subunits; Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily

Top 10 interactors (score): NOP4 (0.999); NOP14 (0.999); NOC2 (0.999); EBP2 (0.999); ERB1 (0.999); DRS1 (0.999); HAS1 (0.999); NOP2 (0.999); BRX1 (0.999); NOP15 (0.998); RPF1 (0.998); KRI1 (0.998); PUF6 (0.998); DBP9 (0.998); DBP10 (0.998); YTM1 (0.998); ECM16 (0.998); NOC3 (0.998); UTP14 (0.997); MAK21 (0.997)

Homologues (species, bitscore): DDX24 (Homo sapiens, 259.6); Ddx24 (Mus musculus, 254.2); LOC553462 (Danio rerio, 273.1); ddx24 (Xenopus tropicalis, 284.3); CG9143 (Drosophila melanogaster, 306.6); F55F8.2 (Caenorhabditis elegans, 259.6); AT3G16840 (Arabidopsis thaliana, 263.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005296.1:511203-513524:+ gene-YBR142W_AKU4011 rna-NM_001178490.1_AKU4011 cds-NP_009700.1_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000179.1:501774-504095:+ gene-YBR142W_BG1 rna-NM_001178490.1_BG1 cds-NP_009700.1_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005504.1:513006-515315:+ gene-YBR142W_Bruggeman rna-NM_001178490.1_Bruggeman cds-NP_009700.1_Bruggeman 98.6 99.4 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:408348-410669:+ gene-YBR142W_CAT1 rna-NM_001178490.1_CAT1 cds-NP_009700.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005360.1:502983-505304:+ gene-YBR142W_CBS1585 rna-NM_001178490.1_CBS1585 cds-NP_009700.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005344.1:511097-513406:+ gene-YBR142W_CBS436 rna-NM_001178490.1_CBS436 cds-NP_009700.1_CBS436 98.6 99.4 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005328.1:600849-603170:+ gene-YBR142W_CBS6412 rna-NM_001178490.1_CBS6412 cds-NP_009700.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005312.1:508618-510939:+ gene-YBR142W_CBS6413 rna-NM_001178490.1_CBS6413 cds-NP_009700.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001523.1:522086-524407:+ gene-YBR142W_CENPK1137D rna-NM_001178490.1_CENPK1137D cds-NP_009700.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005472.1:637225-639546:+ gene-YBR142W_EthanolRed rna-NM_001178490.1_EthanolRed cds-NP_009700.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005536.1:527237-529558:+ gene-YBR142W_FaliES1 rna-NM_001178490.1_FaliES1 cds-NP_009700.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000444.1:50698-53007:+ gene-YBR142W_JAY291 rna-NM_001178490.1_JAY291 cds-NP_009700.1_JAY291 98.7 99.4 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005408.1:515880-518189:+ gene-YBR142W_MUCL30387 rna-NM_001178490.1_MUCL30387 cds-NP_009700.1_MUCL30387 98.6 99.4 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005440.1:515170-517479:+ gene-YBR142W_MUCL30388 rna-NM_001178490.1_MUCL30388 cds-NP_009700.1_MUCL30388 98.6 99.4 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005280.1:501370-503691:+ gene-YBR142W_MUCL39482 rna-NM_001178490.1_MUCL39482 cds-NP_009700.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005424.1:511273-513582:+ gene-YBR142W_MUCL42920 rna-NM_001178490.1_MUCL42920 cds-NP_009700.1_MUCL42920 98.7 99.4 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011811.1:528114-530435:+ gene-YBR142W_NCIM3186 rna-NM_001178490.1_NCIM3186 cds-NP_009700.1_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005264.1:503909-506230:+ gene-YBR142W_NCYC1407 rna-NM_001178490.1_NCYC1407 cds-NP_009700.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994141.1:516544-518853:+ gene-YBR142W_PE2H3 rna-NM_001178490.1_PE2H3 cds-NP_009700.1_PE2H3 98.7 99.4 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999873.1:514220-516529:+ gene-YBR142W_PE2H4 rna-NM_001178490.1_PE2H4 cds-NP_009700.1_PE2H4 98.7 99.4 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001134.8:528317-530638:+ gene-YBR142W_S288C rna-NM_001178490.1_S288C cds-NP_009700.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000032.1:49500-51821:+ gene-YBR142W_SA1 rna-NM_001178490.1_SA1 cds-NP_009700.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005488.1:526250-528571:+ gene-YBR142W_ThermosaccDry rna-NM_001178490.1_ThermosaccDry cds-NP_009700.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005456.1:507749-510070:+ gene-YBR142W_VR1 rna-NM_001178490.1_VR1 cds-NP_009700.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000003.1:501396-503717:+ gene-YBR142W_ZTW1 rna-NM_001178490.1_ZTW1 cds-NP_009700.1_ZTW1 99.7 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047488.1:538636-540945:+ gene-YBR142W_Sparadoxus rna-NM_001178490.1_Sparadoxus cds-NP_009700.1_Sparadoxus 88.8 99.4 Verified 1 1 1 False True False False False

Additional files