Gene name: MAK3
Reference locus (S288C): YPR051W
Gene biotype: protein_coding
Description: N-alpha-acetyltransferase 30; Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT); involved in subcellular targeting of select N-terminally acetylated substrates to the Golgi apparatus (Arl3p and Grh1p) and the inner nuclear membrane (Trm1p); required for replication of dsRNA virus; human NatC ortholog, Naa60, functionally complements the null, requiring either auxiliary subunit Mak10p or co-expression of human ortholog, Naa35; Naa60, the human NatF gene, also complements the null allele; Belongs to the acetyltransferase family. MAK3 subfamily
Top 10 interactors (score): NAT1 (0.999); MAK31 (0.999); MAK10 (0.999); NAT3 (0.998); ARD1 (0.998); MDM20 (0.995); NAT5 (0.989); ARL3 (0.975); PRE5 (0.845); PET18 (0.813); SLI1 (0.813); NAT4 (0.77); SYS1 (0.766); GUF1 (0.707); TOP1 (0.705); GCN5 (0.625); CSL4 (0.617); SPT7 (0.593); PUP2 (0.591); LSM1 (0.58)
Homologues (species, bitscore): NAA30 (Homo sapiens, 152.1); Naa30 (Mus musculus, 150.6); naa30 (Danio rerio, 149.4); naa30 (Xenopus tropicalis, 149.8); Naa30A (Drosophila melanogaster, 142.1); natc-2 (Caenorhabditis elegans, 153.3); ATMAK3 (Arabidopsis thaliana, 137.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:636625-637155:+ | gene-YPR051W_AKU4011 | rna-NM_001184148.1_AKU4011 | cds-NP_015376.1_AKU4011 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:260524-261054:- | gene-YPR051W_BG1 | rna-NM_001184148.1_BG1 | cds-NP_015376.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:714294-714824:+ | gene-YPR051W_Bruggeman | rna-NM_001184148.1_Bruggeman | cds-NP_015376.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:757748-758278:+ | gene-YPR051W_CAT1 | rna-NM_001184148.1_CAT1 | cds-NP_015376.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:640311-640841:+ | gene-YPR051W_CBS1585 | rna-NM_001184148.1_CBS1585 | cds-NP_015376.1_CBS1585 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:654690-655220:+ | gene-YPR051W_CBS436 | rna-NM_001184148.1_CBS436 | cds-NP_015376.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:644059-644589:+ | gene-YPR051W_CBS6412 | rna-NM_001184148.1_CBS6412 | cds-NP_015376.1_CBS6412 | 99.0 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:637260-637790:+ | gene-YPR051W_CBS6413 | rna-NM_001184148.1_CBS6413 | cds-NP_015376.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:664925-665455:+ | gene-YPR051W_CENPK1137D | rna-NM_001184148.1_CENPK1137D | cds-NP_015376.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:963816-964346:+ | gene-YPR051W_EthanolRed | rna-NM_001184148.1_EthanolRed | cds-NP_015376.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:642453-642983:+ | gene-YPR051W_FaliES1 | rna-NM_001184148.1_FaliES1 | cds-NP_015376.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000446.1:14411-14941:+ | gene-YPR051W_JAY291 | rna-NM_001184148.1_JAY291 | cds-NP_015376.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:655555-656085:+ | gene-YPR051W_MUCL30387 | rna-NM_001184148.1_MUCL30387 | cds-NP_015376.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:654259-654789:+ | gene-YPR051W_MUCL30388 | rna-NM_001184148.1_MUCL30388 | cds-NP_015376.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:633568-634098:+ | gene-YPR051W_MUCL39482 | rna-NM_001184148.1_MUCL39482 | cds-NP_015376.1_MUCL39482 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:696396-696926:+ | gene-YPR051W_MUCL42920 | rna-NM_001184148.1_MUCL42920 | cds-NP_015376.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:664943-665473:+ | gene-YPR051W_NCIM3186 | rna-NM_001184148.1_NCIM3186 | cds-NP_015376.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:641498-642028:+ | gene-YPR051W_NCYC1407 | rna-NM_001184148.1_NCYC1407 | cds-NP_015376.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:647714-648244:+ | gene-YPR051W_PE2H3 | rna-NM_001184148.1_PE2H3 | cds-NP_015376.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:647362-647892:+ | gene-YPR051W_PE2H4 | rna-NM_001184148.1_PE2H4 | cds-NP_015376.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:664960-665490:+ | gene-YPR051W_S288C | rna-NM_001184148.1_S288C | cds-NP_015376.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000026.1:35201-35731:- | gene-YPR051W_SA1 | rna-NM_001184148.1_SA1 | cds-NP_015376.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:642228-642758:+ | gene-YPR051W_ThermosaccDry | rna-NM_001184148.1_ThermosaccDry | cds-NP_015376.1_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:658387-658917:+ | gene-YPR051W_VR1 | rna-NM_001184148.1_VR1 | cds-NP_015376.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:641459-641989:+ | gene-YPR051W_ZTW1 | rna-NM_001184148.1_ZTW1 | cds-NP_015376.1_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:642252-642782:+ | gene-YPR051W_Sparadoxus | rna-NM_001184148.1_Sparadoxus | cds-NP_015376.1_Sparadoxus | 92.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |