MAK10 (YEL053C)


Gene profile

Gene name: MAK10
Reference locus (S288C): YEL053C
Gene biotype: protein_coding

Description: N-alpha-acetyltransferase, 35 NatC auxiliary subunit; Non-catalytic subunit of the NatC N-terminal acetyltransferase; required for replication of dsRNA virus; expression is glucose-repressible; human NatC ortholog, Naa35, requires co-expression of the human catalytic subunit, Naa30, to functionally complement the null allele; Belongs to the MAK10 family

Top 10 interactors (score): MAK3 (0.999); MAK31 (0.999); ARD1 (0.994); NAT1 (0.994); MDM20 (0.982); NAT3 (0.978); NAT5 (0.972); ARL3 (0.963); SYS1 (0.852); PET18 (0.847); TRM1 (0.728); VPS54 (0.72); VPS53 (0.717); TOP1 (0.712); GID8 (0.701); MAP2 (0.687); NAT4 (0.687); MON2 (0.685); SMB1 (0.677); RPL8A (0.674)

Homologues (species, bitscore): NAA35 (Homo sapiens, 73.6); Naa35 (Mus musculus, 73.2); naa35 (Danio rerio, 76.6); naa35 (Xenopus tropicalis, 76.3); CG4065 (Drosophila melanogaster, 82.0); MAK10 (Arabidopsis thaliana, 57.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:48306-50507:- gene-YEL053C_AKU4011 rna-NM_001178868.3_AKU4011 cds-NP_010861.3_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000075.1:30009-32210:+ gene-YEL053C_BG1 rna-NM_001178868.3_BG1 cds-NP_010861.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:51825-54026:- gene-YEL053C_Bruggeman rna-NM_001178868.3_Bruggeman cds-NP_010861.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:50248-52449:- gene-YEL053C_CAT1 rna-NM_001178868.3_CAT1 cds-NP_010861.3_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:48253-50454:- gene-YEL053C_CBS1585 rna-NM_001178868.3_CBS1585 cds-NP_010861.3_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:49311-51512:- gene-YEL053C_CBS436 rna-NM_001178868.3_CBS436 cds-NP_010861.3_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:48503-50704:- gene-YEL053C_CBS6412 rna-NM_001178868.3_CBS6412 cds-NP_010861.3_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:53147-55348:- gene-YEL053C_CBS6413 rna-NM_001178868.3_CBS6413 cds-NP_010861.3_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:51741-53942:- gene-YEL053C_CENPK1137D rna-NM_001178868.3_CENPK1137D cds-NP_010861.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:48063-50264:- gene-YEL053C_EthanolRed rna-NM_001178868.3_EthanolRed cds-NP_010861.3_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:48326-50527:- gene-YEL053C_FaliES1 rna-NM_001178868.3_FaliES1 cds-NP_010861.3_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000427.1:7528-9729:+ gene-YEL053C_JAY291 rna-NM_001178868.3_JAY291 cds-NP_010861.3_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:52257-54458:- gene-YEL053C_MUCL30387 rna-NM_001178868.3_MUCL30387 cds-NP_010861.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:48374-50575:- gene-YEL053C_MUCL30388 rna-NM_001178868.3_MUCL30388 cds-NP_010861.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:47620-49821:- gene-YEL053C_MUCL39482 rna-NM_001178868.3_MUCL39482 cds-NP_010861.3_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:52259-54460:- gene-YEL053C_MUCL42920 rna-NM_001178868.3_MUCL42920 cds-NP_010861.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:53900-56101:- gene-YEL053C_NCIM3186 rna-NM_001178868.3_NCIM3186 cds-NP_010861.3_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:52715-54916:- gene-YEL053C_NCYC1407 rna-NM_001178868.3_NCYC1407 cds-NP_010861.3_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:56727-58928:- gene-YEL053C_PE2H3 rna-NM_001178868.3_PE2H3 cds-NP_010861.3_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:52643-54844:- gene-YEL053C_PE2H4 rna-NM_001178868.3_PE2H4 cds-NP_010861.3_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:53901-56102:- gene-YEL053C_S288C rna-NM_001178868.3_S288C cds-NP_010861.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000053.1:30897-33098:+ gene-YEL053C_SA1 rna-NM_001178868.3_SA1 cds-NP_010861.3_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:48726-50927:- gene-YEL053C_ThermosaccDry rna-NM_001178868.3_ThermosaccDry cds-NP_010861.3_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:47934-50135:- gene-YEL053C_VR1 rna-NM_001178868.3_VR1 cds-NP_010861.3_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:47662-49863:- gene-YEL053C_ZTW1 rna-NM_001178868.3_ZTW1 cds-NP_010861.3_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:51908-54109:- gene-YEL053C_Sparadoxus rna-NM_001178868.3_Sparadoxus cds-NP_010861.3_Sparadoxus 89.2 100.0 Verified 1 1 1 False True False False False

Additional files