Gene name: MAD2
Reference locus (S288C): YJL030W
Gene biotype: protein_coding
Description: Component of the spindle-assembly checkpoint complex; delays onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability
Top 10 interactors (score): CDC20 (0.999); MPS1 (0.999); MAD3 (0.999); BUB1 (0.999); CDC16 (0.999); MAD1 (0.999); BUB3 (0.999); PCH2 (0.998); CDC23 (0.998); CDH1 (0.998); DOC1 (0.997); CIN8 (0.997); CDC27 (0.997); APC4 (0.996); APC1 (0.995); IPL1 (0.994); CDC5 (0.992); BUB2 (0.991); NDC80 (0.991); APC2 (0.99)
Homologues (species, bitscore): MAD2L1 (Homo sapiens, 159.8); Mad2l1 (Mus musculus, 161.0); mad2l1 (Danio rerio, 160.6); mad2l1 (Xenopus tropicalis, 159.1); mad2 (Drosophila melanogaster, 140.2); mdf-2 (Caenorhabditis elegans, 146.0); MAD2 (Arabidopsis thaliana, 152.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:370614-371204:+ | gene-YJL030W_AKU4011 | rna-NM_001181464.3_AKU4011 | cds-NP_012504.3_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:242875-243465:- | gene-YJL030W_BG1 | rna-NM_001181464.3_BG1 | cds-NP_012504.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:384813-385403:+ | gene-YJL030W_Bruggeman | rna-NM_001181464.3_Bruggeman | cds-NP_012504.3_Bruggeman | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:388768-389358:+ | gene-YJL030W_CAT1 | rna-NM_001181464.3_CAT1 | cds-NP_012504.3_CAT1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:382280-382870:+ | gene-YJL030W_CBS1585 | rna-NM_001181464.3_CBS1585 | cds-NP_012504.3_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:400641-401231:+ | gene-YJL030W_CBS436 | rna-NM_001181464.3_CBS436 | cds-NP_012504.3_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:370876-371466:+ | gene-YJL030W_CBS6412 | rna-NM_001181464.3_CBS6412 | cds-NP_012504.3_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:372756-373346:+ | gene-YJL030W_CBS6413 | rna-NM_001181464.3_CBS6413 | cds-NP_012504.3_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:370083-370673:+ | gene-YJL030W_CENPK1137D | rna-NM_001181464.3_CENPK1137D | cds-NP_012504.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:373832-374422:+ | gene-YJL030W_EthanolRed | rna-NM_001181464.3_EthanolRed | cds-NP_012504.3_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:386280-386870:+ | gene-YJL030W_FaliES1 | rna-NM_001181464.3_FaliES1 | cds-NP_012504.3_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000200.1:28556-29146:- | gene-YJL030W_JAY291 | rna-NM_001181464.3_JAY291 | cds-NP_012504.3_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:385054-385644:+ | gene-YJL030W_MUCL30387 | rna-NM_001181464.3_MUCL30387 | cds-NP_012504.3_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:381198-381788:+ | gene-YJL030W_MUCL30388 | rna-NM_001181464.3_MUCL30388 | cds-NP_012504.3_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:375604-376194:+ | gene-YJL030W_MUCL39482 | rna-NM_001181464.3_MUCL39482 | cds-NP_012504.3_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:380942-381532:+ | gene-YJL030W_MUCL42920 | rna-NM_001181464.3_MUCL42920 | cds-NP_012504.3_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:387636-388226:+ | gene-YJL030W_NCIM3186 | rna-NM_001181464.3_NCIM3186 | cds-NP_012504.3_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:373551-374141:+ | gene-YJL030W_NCYC1407 | rna-NM_001181464.3_NCYC1407 | cds-NP_012504.3_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:385631-386221:+ | gene-YJL030W_PE2H3 | rna-NM_001181464.3_PE2H3 | cds-NP_012504.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:385277-385867:+ | gene-YJL030W_PE2H4 | rna-NM_001181464.3_PE2H4 | cds-NP_012504.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:387657-388247:+ | gene-YJL030W_S288C | rna-NM_001181464.3_S288C | cds-NP_012504.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:183161-183751:+ | gene-YJL030W_SA1 | rna-NM_001181464.3_SA1 | cds-NP_012504.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:379941-380531:+ | gene-YJL030W_ThermosaccDry | rna-NM_001181464.3_ThermosaccDry | cds-NP_012504.3_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:381787-382377:+ | gene-YJL030W_VR1 | rna-NM_001181464.3_VR1 | cds-NP_012504.3_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:360605-361195:+ | gene-YJL030W_ZTW1 | rna-NM_001181464.3_ZTW1 | cds-NP_012504.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:385853-386443:+ | gene-YJL030W_Sparadoxus | rna-NM_001181464.3_Sparadoxus | cds-NP_012504.3_Sparadoxus | 91.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |