MAC1 (YMR021C)


Gene profile

Gene name: MAC1
Reference locus (S288C): YMR021C
Gene biotype: protein_coding

Description: Metal-binding activator 1; Copper-sensing transcription factor; involved in regulation of genes required for high affinity copper transport; required for regulation of yeast copper genes in response to DNA-damaging agents; undergoes changes in redox state in response to changing levels of copper or MMS

Top 10 interactors (score): CTR3 (0.956); CTR2 (0.948); FRE1 (0.922); AFT1 (0.838); FRE7 (0.785); FRE2 (0.781); FET3 (0.76); REE1 (0.749); IRC7 (0.719); CRS5 (0.715); FTR1 (0.695); CUP1-2 (0.691); FRE3 (0.671); ELO3 (0.655); ELO1 (0.655); ELO2 (0.655); CCC2 (0.653); CDH1 (0.652); FRE6 (0.65); YOR111W (0.645)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005307.1:366772-368025:- gene-YMR021C_AKU4011 rna-NM_001182517.1_AKU4011 cds-NP_013734.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000201.1:174832-176085:+ gene-YMR021C_BG1 rna-NM_001182517.1_BG1 cds-NP_013734.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005515.1:306710-307963:- gene-YMR021C_Bruggeman rna-NM_001182517.1_Bruggeman cds-NP_013734.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005531.1:309224-310477:- gene-YMR021C_CAT1 rna-NM_001182517.1_CAT1 cds-NP_013734.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005371.1:299711-300964:- gene-YMR021C_CBS1585 rna-NM_001182517.1_CBS1585 cds-NP_013734.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005355.1:305254-306507:- gene-YMR021C_CBS436 rna-NM_001182517.1_CBS436 cds-NP_013734.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005339.1:413115-414368:- gene-YMR021C_CBS6412 rna-NM_001182517.1_CBS6412 cds-NP_013734.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005323.1:298969-300222:- gene-YMR021C_CBS6413 rna-NM_001182517.1_CBS6413 cds-NP_013734.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001534.1:311896-313149:- gene-YMR021C_CENPK1137D rna-NM_001182517.1_CENPK1137D cds-NP_013734.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005483.1:299543-300796:- gene-YMR021C_EthanolRed rna-NM_001182517.1_EthanolRed cds-NP_013734.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005547.1:302726-303979:- gene-YMR021C_FaliES1 rna-NM_001182517.1_FaliES1 cds-NP_013734.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000033.1:132963-134216:+ gene-YMR021C_JAY291 rna-NM_001182517.1_JAY291 cds-NP_013734.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005419.1:304671-305924:- gene-YMR021C_MUCL30387 rna-NM_001182517.1_MUCL30387 cds-NP_013734.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005451.1:309096-310349:- gene-YMR021C_MUCL30388 rna-NM_001182517.1_MUCL30388 cds-NP_013734.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005291.1:299996-301249:- gene-YMR021C_MUCL39482 rna-NM_001182517.1_MUCL39482 cds-NP_013734.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005435.1:305811-307064:- gene-YMR021C_MUCL42920 rna-NM_001182517.1_MUCL42920 cds-NP_013734.1_MUCL42920 99.7 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011822.1:317119-318372:- gene-YMR021C_NCIM3186 rna-NM_001182517.1_NCIM3186 cds-NP_013734.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005275.1:299913-301166:- gene-YMR021C_NCYC1407 rna-NM_001182517.1_NCYC1407 cds-NP_013734.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994152.1:305856-307109:- gene-YMR021C_PE2H3 rna-NM_001182517.1_PE2H3 cds-NP_013734.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999884.1:311951-313204:- gene-YMR021C_PE2H4 rna-NM_001182517.1_PE2H4 cds-NP_013734.1_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001145.3:317165-318418:- gene-YMR021C_S288C rna-NM_001182517.1_S288C cds-NP_013734.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000005.1:219848-221101:+ gene-YMR021C_SA1 rna-NM_001182517.1_SA1 cds-NP_013734.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005499.1:299795-301048:- gene-YMR021C_ThermosaccDry rna-NM_001182517.1_ThermosaccDry cds-NP_013734.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005467.1:303744-304997:- gene-YMR021C_VR1 rna-NM_001182517.1_VR1 cds-NP_013734.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000027.1:278810-280063:- gene-YMR021C_ZTW1 rna-NM_001182517.1_ZTW1 cds-NP_013734.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047499.1:312594-313847:- gene-YMR021C_Sparadoxus rna-NM_001182517.1_Sparadoxus cds-NP_013734.1_Sparadoxus 91.0 100.0 Verified 1 1 1 False True False False False

Additional files