Gene name: LYS9
Reference locus (S288C): YNR050C
Gene biotype: protein_coding
Description: Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, the seventh step in lysine biosynthesis pathway; exhibits genetic and physical interactions with TRM112
Top 10 interactors (score): LYS1 (0.999); LYS2 (0.995); LYS12 (0.994); LYS20 (0.971); LYS4 (0.962); TRM112 (0.95); ACO2 (0.945); LYS21 (0.939); PDB1 (0.893); ILV5 (0.888); LAT1 (0.882); SPE3 (0.875); ZUO1 (0.868); ARO8 (0.844); YOR111W (0.813); LYS14 (0.793); ARG3 (0.783); ARG5,6 (0.781); HIS1 (0.774); YHL018W (0.746)
Homologues (species, bitscore): AASS (Homo sapiens, 338.2); Aass (Mus musculus, 324.7); aass (Danio rerio, 325.5); aass (Xenopus tropicalis, 314.7); LKR (Drosophila melanogaster, 313.5); aass-1 (Caenorhabditis elegans, 333.6); AT4G33150 (Arabidopsis thaliana, 265.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:236109-237449:+ | gene-YNR050C_AKU4011 | rna-NM_001183227.1_AKU4011 | cds-NP_014448.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:605587-606927:- | gene-YNR050C_BG1 | rna-NM_001183227.1_BG1 | cds-NP_014448.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:715368-716708:- | gene-YNR050C_Bruggeman | rna-NM_001183227.1_Bruggeman | cds-NP_014448.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:749338-750678:- | gene-YNR050C_CAT1 | rna-NM_001183227.1_CAT1 | cds-NP_014448.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:703588-704928:- | gene-YNR050C_CBS1585 | rna-NM_001183227.1_CBS1585 | cds-NP_014448.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:765131-766471:- | gene-YNR050C_CBS436 | rna-NM_001183227.1_CBS436 | cds-NP_014448.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:692566-693906:- | gene-YNR050C_CBS6412 | rna-NM_001183227.1_CBS6412 | cds-NP_014448.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:694251-695591:- | gene-YNR050C_CBS6413 | rna-NM_001183227.1_CBS6413 | cds-NP_014448.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:707791-709131:- | gene-YNR050C_CENPK1137D | rna-NM_001183227.1_CENPK1137D | cds-NP_014448.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:699230-700570:- | gene-YNR050C_EthanolRed | rna-NM_001183227.1_EthanolRed | cds-NP_014448.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:690433-691773:- | gene-YNR050C_FaliES1 | rna-NM_001183227.1_FaliES1 | cds-NP_014448.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000037.1:10869-12209:+ | gene-YNR050C_JAY291 | rna-NM_001183227.1_JAY291 | cds-NP_014448.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:713296-714636:- | gene-YNR050C_MUCL30387 | rna-NM_001183227.1_MUCL30387 | cds-NP_014448.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:754356-755696:- | gene-YNR050C_MUCL30388 | rna-NM_001183227.1_MUCL30388 | cds-NP_014448.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:695057-696397:- | gene-YNR050C_MUCL39482 | rna-NM_001183227.1_MUCL39482 | cds-NP_014448.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:699769-701109:- | gene-YNR050C_MUCL42920 | rna-NM_001183227.1_MUCL42920 | cds-NP_014448.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:714017-715357:- | gene-YNR050C_NCIM3186 | rna-NM_001183227.1_NCIM3186 | cds-NP_014448.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:697575-698915:- | gene-YNR050C_NCYC1407 | rna-NM_001183227.1_NCYC1407 | cds-NP_014448.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:698440-699780:- | gene-YNR050C_PE2H3 | rna-NM_001183227.1_PE2H3 | cds-NP_014448.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:699842-701182:- | gene-YNR050C_PE2H4 | rna-NM_001183227.1_PE2H4 | cds-NP_014448.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:714048-715388:- | gene-YNR050C_S288C | rna-NM_001183227.1_S288C | cds-NP_014448.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000074.1:10931-12271:+ | gene-YNR050C_SA1 | rna-NM_001183227.1_SA1 | cds-NP_014448.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:690770-692110:- | gene-YNR050C_ThermosaccDry | rna-NM_001183227.1_ThermosaccDry | cds-NP_014448.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:732899-734239:- | gene-YNR050C_VR1 | rna-NM_001183227.1_VR1 | cds-NP_014448.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:600544-601884:- | gene-YNR050C_ZTW1 | rna-NM_001183227.1_ZTW1 | cds-NP_014448.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:705006-706346:- | gene-YNR050C_Sparadoxus | rna-NM_001183227.1_Sparadoxus | cds-NP_014448.1_Sparadoxus | 91.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |