LYS5 (YGL154C)


Gene profile

Gene name: LYS5
Reference locus (S288C): YGL154C
Gene biotype: protein_coding

Description: L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine; Belongs to the P-Pant transferase superfamily. AcpS family

Top 10 interactors (score): LYS2 (0.986); CAB5 (0.951); ADE1 (0.902); ADE3 (0.897); LYS12 (0.846); ADE5,7 (0.792); URA3 (0.786); HHF1 (0.767); HHF2 (0.767); THR4 (0.733); HIS4 (0.732); LYS14 (0.715); LYS9 (0.699); LYS1 (0.699); YCL021W-A (0.698); TRP3 (0.695); ACP1 (0.682); TRP5 (0.665); MET13 (0.624); RPL28 (0.619)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:217874-218692:- gene-YGL154C_AKU4011 rna-NM_001181019.1_AKU4011 cds-NP_011361.1_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:186265-187083:+ gene-YGL154C_BG1 rna-NM_001181019.1_BG1 cds-NP_011361.1_BG1 99.1 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:220017-220835:- gene-YGL154C_Bruggeman rna-NM_001181019.1_Bruggeman cds-NP_011361.1_Bruggeman 99.1 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:215884-216702:- gene-YGL154C_CAT1 rna-NM_001181019.1_CAT1 cds-NP_011361.1_CAT1 99.2 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:221257-222075:- gene-YGL154C_CBS1585 rna-NM_001181019.1_CBS1585 cds-NP_011361.1_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:215865-216683:- gene-YGL154C_CBS436 rna-NM_001181019.1_CBS436 cds-NP_011361.1_CBS436 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:207466-208284:- gene-YGL154C_CBS6412 rna-NM_001181019.1_CBS6412 cds-NP_011361.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:215810-216628:- gene-YGL154C_CBS6413 rna-NM_001181019.1_CBS6413 cds-NP_011361.1_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:215540-216358:- gene-YGL154C_CENPK1137D rna-NM_001181019.1_CENPK1137D cds-NP_011361.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:208018-208836:- gene-YGL154C_EthanolRed rna-NM_001181019.1_EthanolRed cds-NP_011361.1_EthanolRed 99.0 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:209264-210082:- gene-YGL154C_FaliES1 rna-NM_001181019.1_FaliES1 cds-NP_011361.1_FaliES1 99.0 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000090.1:59085-59903:- gene-YGL154C_JAY291 rna-NM_001181019.1_JAY291 cds-NP_011361.1_JAY291 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:217242-218060:- gene-YGL154C_MUCL30387 rna-NM_001181019.1_MUCL30387 cds-NP_011361.1_MUCL30387 99.1 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:220357-221175:- gene-YGL154C_MUCL30388 rna-NM_001181019.1_MUCL30388 cds-NP_011361.1_MUCL30388 99.1 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:218037-218855:- gene-YGL154C_MUCL39482 rna-NM_001181019.1_MUCL39482 cds-NP_011361.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:220593-221411:- gene-YGL154C_MUCL42920 rna-NM_001181019.1_MUCL42920 cds-NP_011361.1_MUCL42920 98.9 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:215278-216096:- gene-YGL154C_NCIM3186 rna-NM_001181019.1_NCIM3186 cds-NP_011361.1_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:209501-210319:- gene-YGL154C_NCYC1407 rna-NM_001181019.1_NCYC1407 cds-NP_011361.1_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:211387-212205:- gene-YGL154C_PE2H3 rna-NM_001181019.1_PE2H3 cds-NP_011361.1_PE2H3 99.1 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:216382-217200:- gene-YGL154C_PE2H4 rna-NM_001181019.1_PE2H4 cds-NP_011361.1_PE2H4 99.1 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:215278-216096:- gene-YGL154C_S288C rna-NM_001181019.1_S288C cds-NP_011361.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000081.1:38653-39471:+ gene-YGL154C_SA1 rna-NM_001181019.1_SA1 cds-NP_011361.1_SA1 98.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:209493-210311:- gene-YGL154C_ThermosaccDry rna-NM_001181019.1_ThermosaccDry cds-NP_011361.1_ThermosaccDry 99.0 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:216301-217119:- gene-YGL154C_VR1 rna-NM_001181019.1_VR1 cds-NP_011361.1_VR1 99.1 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:207597-208415:- gene-YGL154C_ZTW1 rna-NM_001181019.1_ZTW1 cds-NP_011361.1_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:213665-214483:- gene-YGL154C_Sparadoxus rna-NM_001181019.1_Sparadoxus cds-NP_011361.1_Sparadoxus 86.5 100.0 Verified 1 1 1 False True False False False

Additional files