Gene name: LST7
Reference locus (S288C): YGR057C
Gene biotype: protein_coding
Description: Protein LST7; Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p; stimulates the GTPase activity of Rag family GTPase Gtr2p, within the context of the Gtr1p-Gtr2p heterodimer, after amino acid stimulation; required for activation of TORC1 in response to amino acid stimulation; recruited to the vacuolar membrane during amino acid starvation and released from the membrane by TORC1; required for the transport of amino acid permease Gap1p from the Golgi to the cell surface
Top 10 interactors (score): LST4 (0.997); SEC13 (0.971); GTR2 (0.969); SEA4 (0.962); GTR1 (0.959); MTC5 (0.946); NPR2 (0.942); LST8 (0.939); BUB2 (0.904); BFA1 (0.9); RTC1 (0.894); CDC60 (0.858); VAM6 (0.809); PIB2 (0.807); SEH1 (0.792); IML1 (0.775); GAP1 (0.758); SLM4 (0.754); MEH1 (0.748); EGO2 (0.747)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:588470-589198:- | gene-YGR057C_AKU4011 | rna-NM_001181186.3_AKU4011 | cds-NP_011571.4_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000173.1:24867-25595:- | gene-YGR057C_BG1 | rna-NM_001181186.3_BG1 | cds-NP_011571.4_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:590752-591480:- | gene-YGR057C_Bruggeman | rna-NM_001181186.3_Bruggeman | cds-NP_011571.4_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:589178-589906:- | gene-YGR057C_CAT1 | rna-NM_001181186.3_CAT1 | cds-NP_011571.4_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:589784-590512:- | gene-YGR057C_CBS1585 | rna-NM_001181186.3_CBS1585 | cds-NP_011571.4_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:591076-591804:- | gene-YGR057C_CBS436 | rna-NM_001181186.3_CBS436 | cds-NP_011571.4_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:582579-583307:- | gene-YGR057C_CBS6412 | rna-NM_001181186.3_CBS6412 | cds-NP_011571.4_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:586581-587309:- | gene-YGR057C_CBS6413 | rna-NM_001181186.3_CBS6413 | cds-NP_011571.4_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:604511-605239:- | gene-YGR057C_CENPK1137D | rna-NM_001181186.3_CENPK1137D | cds-NP_011571.4_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:576712-577440:- | gene-YGR057C_EthanolRed | rna-NM_001181186.3_EthanolRed | cds-NP_011571.4_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:580196-580924:- | gene-YGR057C_FaliES1 | rna-NM_001181186.3_FaliES1 | cds-NP_011571.4_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000435.1:31137-31865:- | gene-YGR057C_JAY291 | rna-NM_001181186.3_JAY291 | cds-NP_011571.4_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:587387-588115:- | gene-YGR057C_MUCL30387 | rna-NM_001181186.3_MUCL30387 | cds-NP_011571.4_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:590781-591509:- | gene-YGR057C_MUCL30388 | rna-NM_001181186.3_MUCL30388 | cds-NP_011571.4_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:585601-586329:- | gene-YGR057C_MUCL39482 | rna-NM_001181186.3_MUCL39482 | cds-NP_011571.4_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:595411-596139:- | gene-YGR057C_MUCL42920 | rna-NM_001181186.3_MUCL42920 | cds-NP_011571.4_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:604773-605501:- | gene-YGR057C_NCIM3186 | rna-NM_001181186.3_NCIM3186 | cds-NP_011571.4_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:579799-580527:- | gene-YGR057C_NCYC1407 | rna-NM_001181186.3_NCYC1407 | cds-NP_011571.4_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:583039-583767:- | gene-YGR057C_PE2H3 | rna-NM_001181186.3_PE2H3 | cds-NP_011571.4_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:588146-588874:- | gene-YGR057C_PE2H4 | rna-NM_001181186.3_PE2H4 | cds-NP_011571.4_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:604773-605501:- | gene-YGR057C_S288C | rna-NM_001181186.3_S288C | cds-NP_011571.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000015.1:31237-31965:- | gene-YGR057C_SA1 | rna-NM_001181186.3_SA1 | cds-NP_011571.4_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:599533-600261:- | gene-YGR057C_ThermosaccDry | rna-NM_001181186.3_ThermosaccDry | cds-NP_011571.4_ThermosaccDry | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:696459-697187:- | gene-YGR057C_VR1 | rna-NM_001181186.3_VR1 | cds-NP_011571.4_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000015.1:55008-55736:- | gene-YGR057C_ZTW1 | rna-NM_001181186.3_ZTW1 | cds-NP_011571.4_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:590038-590766:- | gene-YGR057C_Sparadoxus | rna-NM_001181186.3_Sparadoxus | cds-NP_011571.4_Sparadoxus | 92.1 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |