LSM6 (YDR378C)


Gene profile

Gene name: LSM6
Reference locus (S288C): YDR378C
Gene biotype: protein_coding

Description: U6 snRNA-associated Sm-like protein LSm6; Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily

Top 10 interactors (score): PRP31 (0.999); PRP3 (0.999); PRP24 (0.999); LSM1 (0.999); PRP4 (0.999); LSM3 (0.999); LSM7 (0.999); PAT1 (0.999); LSM8 (0.999); SMX3 (0.999); SMX2 (0.999); SMD2 (0.999); SNU66 (0.999); SMD3 (0.999); SMB1 (0.999); LSM5 (0.999); SMD1 (0.999); CLF1 (0.999); LSM4 (0.999); SME1 (0.999)

Homologues (species, bitscore): LSM6 (Homo sapiens, 67.0); Lsm6 (Mus musculus, 67.0); lsm6 (Danio rerio, 66.6); lsm6 (Xenopus tropicalis, 67.0); CG9344 (Drosophila melanogaster, 61.2); lsm-6 (Caenorhabditis elegans, 64.7); LSM6B (Arabidopsis thaliana, 60.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:564742-565002:- gene-YDR378C_AKU4011 rna-NM_001180686.1_AKU4011 cds-NP_010666.2_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:48041-48301:- gene-YDR378C_BG1 rna-NM_001180686.1_BG1 cds-NP_010666.2_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1200125-1200385:- gene-YDR378C_Bruggeman rna-NM_001180686.1_Bruggeman cds-NP_010666.2_Bruggeman 99.2 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1178733-1178993:- gene-YDR378C_CAT1 rna-NM_001180686.1_CAT1 cds-NP_010666.2_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1164234-1164494:- gene-YDR378C_CBS1585 rna-NM_001180686.1_CBS1585 cds-NP_010666.2_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1182788-1183048:- gene-YDR378C_CBS436 rna-NM_001180686.1_CBS436 cds-NP_010666.2_CBS436 98.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1160471-1160731:- gene-YDR378C_CBS6412 rna-NM_001180686.1_CBS6412 cds-NP_010666.2_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1182361-1182621:- gene-YDR378C_CBS6413 rna-NM_001180686.1_CBS6413 cds-NP_010666.2_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1228001-1228261:- gene-YDR378C_CENPK1137D rna-NM_001180686.1_CENPK1137D cds-NP_010666.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1173889-1174149:- gene-YDR378C_EthanolRed rna-NM_001180686.1_EthanolRed cds-NP_010666.2_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1177176-1177436:- gene-YDR378C_FaliES1 rna-NM_001180686.1_FaliES1 cds-NP_010666.2_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000057.1:13643-13903:+ gene-YDR378C_JAY291 rna-NM_001180686.1_JAY291 cds-NP_010666.2_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1183444-1183704:- gene-YDR378C_MUCL30387 rna-NM_001180686.1_MUCL30387 cds-NP_010666.2_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1166052-1166312:- gene-YDR378C_MUCL30388 rna-NM_001180686.1_MUCL30388 cds-NP_010666.2_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1155785-1156045:- gene-YDR378C_MUCL39482 rna-NM_001180686.1_MUCL39482 cds-NP_010666.2_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1098176-1098436:- gene-YDR378C_MUCL42920 rna-NM_001180686.1_MUCL42920 cds-NP_010666.2_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1229272-1229532:- gene-YDR378C_NCIM3186 rna-NM_001180686.1_NCIM3186 cds-NP_010666.2_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1169756-1170016:- gene-YDR378C_NCYC1407 rna-NM_001180686.1_NCYC1407 cds-NP_010666.2_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1179840-1180100:- gene-YDR378C_PE2H3 rna-NM_001180686.1_PE2H3 cds-NP_010666.2_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1185422-1185682:- gene-YDR378C_PE2H4 rna-NM_001180686.1_PE2H4 cds-NP_010666.2_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1229349-1229609:- gene-YDR378C_S288C rna-NM_001180686.1_S288C cds-NP_010666.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000072.1:48122-48382:- gene-YDR378C_SA1 rna-NM_001180686.1_SA1 cds-NP_010666.2_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1181457-1181717:- gene-YDR378C_ThermosaccDry rna-NM_001180686.1_ThermosaccDry cds-NP_010666.2_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:608801-609061:- gene-YDR378C_VR1 rna-NM_001180686.1_VR1 cds-NP_010666.2_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:224287-224547:- gene-YDR378C_ZTW1 rna-NM_001180686.1_ZTW1 cds-NP_010666.2_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1176035-1176295:- gene-YDR378C_Sparadoxus rna-NM_001180686.1_Sparadoxus cds-NP_010666.2_Sparadoxus 89.2 100.0 Verified 1 1 1 False True False False False

Additional files