LSC2 (YGR244C)


Gene profile

Gene name: LSC2
Reference locus (S288C): YGR244C
Gene biotype: protein_coding

Description: Succinate--coa ligase [adp-forming] subunit beta, mitochondrial; Beta subunit of succinyl-CoA ligase; succinyl-CoA ligase is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate

Top 10 interactors (score): LSC1 (0.999); KGD2 (0.999); KGD1 (0.998); IDH2 (0.998); LPD1 (0.997); LYS12 (0.991); PDB1 (0.98); SDH1 (0.978); LAT1 (0.965); FUM1 (0.961); SDH3 (0.957); YJL045W (0.955); SDH2 (0.954); ATP3 (0.952); ACO1 (0.948); ACH1 (0.946); IRC15 (0.945); CYT1 (0.945); RIP1 (0.933); ACS1 (0.92)

Homologues (species, bitscore): SUCLA2 (Homo sapiens, 407.5); Sucla2 (Mus musculus, 411.0); sucla2 (Danio rerio, 417.5); sucla2 (Xenopus tropicalis, 421.0); skap (Drosophila melanogaster, 384.4); suca-1 (Caenorhabditis elegans, 388.3); AT2G20420 (Arabidopsis thaliana, 379.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:943450-944733:- gene-YGR244C_AKU4011 rna-NM_001181373.3_AKU4011 cds-NP_011760.3_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000021.1:223545-224828:- gene-YGR244C_BG1 rna-NM_001181373.3_BG1 cds-NP_011760.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:951042-952325:- gene-YGR244C_Bruggeman rna-NM_001181373.3_Bruggeman cds-NP_011760.3_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:950557-951840:- gene-YGR244C_CAT1 rna-NM_001181373.3_CAT1 cds-NP_011760.3_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:946307-947590:- gene-YGR244C_CBS1585 rna-NM_001181373.3_CBS1585 cds-NP_011760.3_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:949958-951241:- gene-YGR244C_CBS436 rna-NM_001181373.3_CBS436 cds-NP_011760.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:937190-938473:- gene-YGR244C_CBS6412 rna-NM_001181373.3_CBS6412 cds-NP_011760.3_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:943241-944524:- gene-YGR244C_CBS6413 rna-NM_001181373.3_CBS6413 cds-NP_011760.3_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:977717-979000:- gene-YGR244C_CENPK1137D rna-NM_001181373.3_CENPK1137D cds-NP_011760.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:931280-932563:- gene-YGR244C_EthanolRed rna-NM_001181373.3_EthanolRed cds-NP_011760.3_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:936086-937369:- gene-YGR244C_FaliES1 rna-NM_001181373.3_FaliES1 cds-NP_011760.3_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000076.1:92923-94206:+ gene-YGR244C_JAY291 rna-NM_001181373.3_JAY291 cds-NP_011760.3_JAY291 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:948958-950241:- gene-YGR244C_MUCL30387 rna-NM_001181373.3_MUCL30387 cds-NP_011760.3_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:948223-949506:- gene-YGR244C_MUCL30388 rna-NM_001181373.3_MUCL30388 cds-NP_011760.3_MUCL30388 99.9 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:941430-942713:- gene-YGR244C_MUCL39482 rna-NM_001181373.3_MUCL39482 cds-NP_011760.3_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:959936-961219:- gene-YGR244C_MUCL42920 rna-NM_001181373.3_MUCL42920 cds-NP_011760.3_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:978036-979319:- gene-YGR244C_NCIM3186 rna-NM_001181373.3_NCIM3186 cds-NP_011760.3_NCIM3186 99.9 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:937050-938333:- gene-YGR244C_NCYC1407 rna-NM_001181373.3_NCYC1407 cds-NP_011760.3_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:962228-963511:- gene-YGR244C_PE2H3 rna-NM_001181373.3_PE2H3 cds-NP_011760.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:967067-968350:- gene-YGR244C_PE2H4 rna-NM_001181373.3_PE2H4 cds-NP_011760.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:978036-979319:- gene-YGR244C_S288C rna-NM_001181373.3_S288C cds-NP_011760.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000045.1:22178-23461:+ gene-YGR244C_SA1 rna-NM_001181373.3_SA1 cds-NP_011760.3_SA1 99.8 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:956613-957896:- gene-YGR244C_ThermosaccDry rna-NM_001181373.3_ThermosaccDry cds-NP_011760.3_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:1061874-1063157:- gene-YGR244C_VR1 rna-NM_001181373.3_VR1 cds-NP_011760.3_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:258021-259304:- gene-YGR244C_ZTW1 rna-NM_001181373.3_ZTW1 cds-NP_011760.3_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:948842-950125:- gene-YGR244C_Sparadoxus rna-NM_001181373.3_Sparadoxus cds-NP_011760.3_Sparadoxus 92.1 100.0 Verified 1 1 1 False True False False False

Additional files