Gene name: LSC1
Reference locus (S288C): YOR142W
Gene biotype: protein_coding
Description: Alpha subunit of succinyl-CoA ligase; succinyl-CoA ligase is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate; phosphorylated
Top 10 interactors (score): KGD2 (0.999); LSC2 (0.999); SDH2 (0.999); IDH1 (0.999); KGD1 (0.999); LAT1 (0.993); FUM1 (0.991); IDH2 (0.988); LPD1 (0.988); MDH1 (0.988); SDH1 (0.986); SDH3 (0.985); ACO1 (0.983); CIT1 (0.981); MDH3 (0.98); PDB1 (0.979); YJL045W (0.975); MLS1 (0.972); MDH2 (0.969); ATP1 (0.969)
Homologues (species, bitscore): SUCLG1 (Homo sapiens, 355.1); Suclg1 (Mus musculus, 350.1); suclg1 (Danio rerio, 345.9); suclg1 (Xenopus tropicalis, 317.0); Scsalpha (Drosophila melanogaster, 335.9); sucl-1 (Caenorhabditis elegans, 337.4); AT5G23250 (Arabidopsis thaliana, 309.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:596511-597500:+ | gene-YOR142W_AKU4011 | rna-NM_001183561.3_AKU4011 | cds-NP_014785.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:1108-2097:- | gene-YOR142W_BG1 | rna-NM_001183561.3_BG1 | cds-NP_014785.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:580672-581661:+ | gene-YOR142W_Bruggeman | rna-NM_001183561.3_Bruggeman | cds-NP_014785.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:580692-581681:+ | gene-YOR142W_CAT1 | rna-NM_001183561.3_CAT1 | cds-NP_014785.3_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:572689-573678:+ | gene-YOR142W_CBS1585 | rna-NM_001183561.3_CBS1585 | cds-NP_014785.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:577396-578385:+ | gene-YOR142W_CBS436 | rna-NM_001183561.3_CBS436 | cds-NP_014785.3_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:570178-571167:+ | gene-YOR142W_CBS6412 | rna-NM_001183561.3_CBS6412 | cds-NP_014785.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:578972-579961:+ | gene-YOR142W_CBS6413 | rna-NM_001183561.3_CBS6413 | cds-NP_014785.3_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:592808-593797:+ | gene-YOR142W_CENPK1137D | rna-NM_001183561.3_CENPK1137D | cds-NP_014785.3_CENPK1137D | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:572823-573812:+ | gene-YOR142W_EthanolRed | rna-NM_001183561.3_EthanolRed | cds-NP_014785.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:577676-578665:+ | gene-YOR142W_FaliES1 | rna-NM_001183561.3_FaliES1 | cds-NP_014785.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000070.1:64885-65874:- | gene-YOR142W_JAY291 | rna-NM_001183561.3_JAY291 | cds-NP_014785.3_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:585229-586218:+ | gene-YOR142W_MUCL30387 | rna-NM_001183561.3_MUCL30387 | cds-NP_014785.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:591310-592299:+ | gene-YOR142W_MUCL30388 | rna-NM_001183561.3_MUCL30388 | cds-NP_014785.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:580763-581752:+ | gene-YOR142W_MUCL39482 | rna-NM_001183561.3_MUCL39482 | cds-NP_014785.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:596363-597352:+ | gene-YOR142W_MUCL42920 | rna-NM_001183561.3_MUCL42920 | cds-NP_014785.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:592946-593935:+ | gene-YOR142W_NCIM3186 | rna-NM_001183561.3_NCIM3186 | cds-NP_014785.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:587031-588020:+ | gene-YOR142W_NCYC1407 | rna-NM_001183561.3_NCYC1407 | cds-NP_014785.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:585537-586526:+ | gene-YOR142W_PE2H3 | rna-NM_001183561.3_PE2H3 | cds-NP_014785.3_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:595914-596903:+ | gene-YOR142W_PE2H4 | rna-NM_001183561.3_PE2H4 | cds-NP_014785.3_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:593057-594046:+ | gene-YOR142W_S288C | rna-NM_001183561.3_S288C | cds-NP_014785.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:15523-16512:+ | gene-YOR142W_SA1 | rna-NM_001183561.3_SA1 | cds-NP_014785.3_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:576859-577848:+ | gene-YOR142W_ThermosaccDry | rna-NM_001183561.3_ThermosaccDry | cds-NP_014785.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:640537-641526:+ | gene-YOR142W_VR1 | rna-NM_001183561.3_VR1 | cds-NP_014785.3_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:310307-311296:+ | gene-YOR142W_ZTW1 | rna-NM_001183561.3_ZTW1 | cds-NP_014785.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:581700-582689:+ | gene-YOR142W_Sparadoxus | rna-NM_001183561.3_Sparadoxus | cds-NP_014785.3_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |