LSB5 (YCL034W)


Gene profile

Gene name: LSB5
Reference locus (S288C): YCL034W
Gene biotype: protein_coding

Description: Protein involved in membrane-trafficking events at plasma membrane; interacts with actin regulators Sla1p and Las17p, ubiquitin, Arf3p to couple actin dynamics to membrane trafficking processes; similar structure to GGA family of proteins with N-terminal VHS domain and GAT domain; binds Las17p, which is homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly, actin polymerization; may mediate disassembly of Pan1 complex from endocytic coat; Belongs to the LSB5 family

Top 10 interactors (score): ARF3 (0.958); SLA1 (0.944); YSC84 (0.896); ARL1 (0.882); LAS17 (0.856); GTS1 (0.767); YEL1 (0.748); PRK1 (0.712); PAN1 (0.675); ABP1 (0.672); ARK1 (0.656); SWA2 (0.619); INP52 (0.618); SLA2 (0.618); SYT1 (0.611); AIM3 (0.593); ACT1 (0.566); MXR2 (0.537); LSB1 (0.529); SCP1 (0.454)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:63020-64084:+ gene-YCL034W_AKU4011 rna-NM_001178679.1_AKU4011 cds-NP_009896.2_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000178.1:83029-84093:- gene-YCL034W_BG1 rna-NM_001178679.1_BG1 cds-NP_009896.2_BG1 99.8 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:51211-52275:+ gene-YCL034W_Bruggeman rna-NM_001178679.1_Bruggeman cds-NP_009896.2_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:62816-63880:+ gene-YCL034W_CAT1 rna-NM_001178679.1_CAT1 cds-NP_009896.2_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:63707-64771:+ gene-YCL034W_CBS1585 rna-NM_001178679.1_CBS1585 cds-NP_009896.2_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:62154-63218:+ gene-YCL034W_CBS436 rna-NM_001178679.1_CBS436 cds-NP_009896.2_CBS436 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:51109-52173:+ gene-YCL034W_CBS6412 rna-NM_001178679.1_CBS6412 cds-NP_009896.2_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:62481-63545:+ gene-YCL034W_CBS6413 rna-NM_001178679.1_CBS6413 cds-NP_009896.2_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:61255-62319:+ gene-YCL034W_CENPK1137D rna-NM_001178679.1_CENPK1137D cds-NP_009896.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:61043-62107:+ gene-YCL034W_EthanolRed rna-NM_001178679.1_EthanolRed cds-NP_009896.2_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:61983-63047:+ gene-YCL034W_FaliES1 rna-NM_001178679.1_FaliES1 cds-NP_009896.2_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000225.1:21336-22400:- gene-YCL034W_JAY291 rna-NM_001178679.1_JAY291 cds-NP_009896.2_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:49407-50471:+ gene-YCL034W_MUCL30387 rna-NM_001178679.1_MUCL30387 cds-NP_009896.2_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:49680-50744:+ gene-YCL034W_MUCL30388 rna-NM_001178679.1_MUCL30388 cds-NP_009896.2_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:64076-65140:+ gene-YCL034W_MUCL39482 rna-NM_001178679.1_MUCL39482 cds-NP_009896.2_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:50192-51256:+ gene-YCL034W_MUCL42920 rna-NM_001178679.1_MUCL42920 cds-NP_009896.2_MUCL42920 99.9 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:61290-62354:+ gene-YCL034W_NCIM3186 rna-NM_001178679.1_NCIM3186 cds-NP_009896.2_NCIM3186 99.0 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:64564-65628:+ gene-YCL034W_NCYC1407 rna-NM_001178679.1_NCYC1407 cds-NP_009896.2_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:62111-63175:+ gene-YCL034W_PE2H3 rna-NM_001178679.1_PE2H3 cds-NP_009896.2_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:62068-63132:+ gene-YCL034W_PE2H4 rna-NM_001178679.1_PE2H4 cds-NP_009896.2_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:61658-62722:+ gene-YCL034W_S288C rna-NM_001178679.1_S288C cds-NP_009896.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000061.1:48796-49860:+ gene-YCL034W_SA1 rna-NM_001178679.1_SA1 cds-NP_009896.2_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:62304-63368:+ gene-YCL034W_ThermosaccDry rna-NM_001178679.1_ThermosaccDry cds-NP_009896.2_ThermosaccDry 99.3 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:68600-69664:+ gene-YCL034W_VR1 rna-NM_001178679.1_VR1 cds-NP_009896.2_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:62504-63568:+ gene-YCL034W_ZTW1 rna-NM_001178679.1_ZTW1 cds-NP_009896.2_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:92052-93116:+ gene-YCL034W_Sparadoxus rna-NM_001178679.1_Sparadoxus cds-NP_009896.2_Sparadoxus 91.2 100.0 Verified 1 1 1 False True False False False

Additional files