Gene name: LSB3
Reference locus (S288C): YFR024C-A
Gene biotype: protein_coding
Description: Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; protein abundance increases in response to DNA replication stress; LSB3 has a paralog, YSC84, that arose from the whole genome duplication
Top 10 interactors (score): YSC84 (0.999); SLA1 (0.991); LAS17 (0.984); CUE5 (0.932); ERG12 (0.918); BZZ1 (0.87); BBC1 (0.865); BSP1 (0.852); MYO5 (0.845); GTS1 (0.816); ABP1 (0.812); HUA1 (0.772); AIM21 (0.758); MYO3 (0.749); BOI2 (0.738); END3 (0.737); YPR089W (0.716); RVS161 (0.712); JIP4 (0.699); TPH3 (0.69)
Homologues (species, bitscore): SH3YL1 (Homo sapiens, 248.8); Sh3yl1 (Mus musculus, 245.7); sh3yl1 (Danio rerio, 252.3); sh3yl1 (Xenopus tropicalis, 222.6); Drk (Drosophila melanogaster, 65.5); itsn-1 (Caenorhabditis elegans, 67.4); AT3G43230 (Arabidopsis thaliana, 165.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKU4011 | GCA_001738255.1 | Sake | Asia | CM005300.1:192165-193638:- | gene-YFR024C-A_AKU4011 | rna-NM_001180865.3_AKU4011 | cds-NP_219497.4_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000071.1:67026-68499:+ | gene-YFR024C-A_BG1 | rna-NM_001180865.3_BG1 | cds-NP_219497.4_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005508.1:195005-196478:- | gene-YFR024C-A_Bruggeman | rna-NM_001180865.3_Bruggeman | cds-NP_219497.4_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005524.1:197534-199007:- | gene-YFR024C-A_CAT1 | rna-NM_001180865.3_CAT1 | cds-NP_219497.4_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
CBS1585 | GCA_001738375.1 | Sake | Asia | CM005364.1:193656-195129:- | gene-YFR024C-A_CBS1585 | rna-NM_001180865.3_CBS1585 | cds-NP_219497.4_CBS1585 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS436 | GCA_001738355.1 | Sake | Asia | CM005348.1:166886-168359:- | gene-YFR024C-A_CBS436 | rna-NM_001180865.3_CBS436 | cds-NP_219497.4_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
CBS6412 | GCA_001738345.1 | Sake | Asia | CM005332.1:192737-194210:- | gene-YFR024C-A_CBS6412 | rna-NM_001180865.3_CBS6412 | cds-NP_219497.4_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6413 | GCA_001738265.1 | Sake | Asia | CM005316.1:195392-196865:- | gene-YFR024C-A_CBS6413 | rna-NM_001180865.3_CBS6413 | cds-NP_219497.4_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001527.1:198001-199474:- | gene-YFR024C-A_CENPK1137D | rna-NM_001180865.3_CENPK1137D | cds-NP_219497.4_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005476.1:191273-192746:- | gene-YFR024C-A_EthanolRed | rna-NM_001180865.3_EthanolRed | cds-NP_219497.4_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005540.1:192923-194396:- | gene-YFR024C-A_FaliES1 | rna-NM_001180865.3_FaliES1 | cds-NP_219497.4_FaliES1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000452.1:39679-41152:- | gene-YFR024C-A_JAY291 | rna-NM_001180865.3_JAY291 | cds-NP_219497.4_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005412.1:195484-196957:- | gene-YFR024C-A_MUCL30387 | rna-NM_001180865.3_MUCL30387 | cds-NP_219497.4_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005444.1:191741-193214:- | gene-YFR024C-A_MUCL30388 | rna-NM_001180865.3_MUCL30388 | cds-NP_219497.4_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005284.1:191575-193048:- | gene-YFR024C-A_MUCL39482 | rna-NM_001180865.3_MUCL39482 | cds-NP_219497.4_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005428.1:190883-192356:- | gene-YFR024C-A_MUCL42920 | rna-NM_001180865.3_MUCL42920 | cds-NP_219497.4_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011815.1:201959-203432:- | gene-YFR024C-A_NCIM3186 | rna-NM_001180865.3_NCIM3186 | cds-NP_219497.4_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005268.1:192457-193930:- | gene-YFR024C-A_NCYC1407 | rna-NM_001180865.3_NCYC1407 | cds-NP_219497.4_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994145.1:234893-236366:- | gene-YFR024C-A_PE2H3 | rna-NM_001180865.3_PE2H3 | cds-NP_219497.4_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999877.1:234441-235914:- | gene-YFR024C-A_PE2H4 | rna-NM_001180865.3_PE2H4 | cds-NP_219497.4_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001138.5:201960-203433:- | gene-YFR024C-A_S288C | rna-NM_001180865.3_S288C | cds-NP_219497.4_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:121003-122476:+ | gene-YFR024C-A_SA1 | rna-NM_001180865.3_SA1 | cds-NP_219497.4_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005492.1:192080-193553:- | gene-YFR024C-A_ThermosaccDry | rna-NM_001180865.3_ThermosaccDry | cds-NP_219497.4_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
VR1 | GCA_001738595.1 | Bioethanol | South America | CM005460.1:208124-209597:- | gene-YFR024C-A_VR1 | rna-NM_001180865.3_VR1 | cds-NP_219497.4_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000013.1:122553-124026:- | gene-YFR024C-A_ZTW1 | rna-NM_001180865.3_ZTW1 | cds-NP_219497.4_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047492.1:216037-217513:- | gene-YFR024C-A_Sparadoxus | rna-NM_001180865.3_Sparadoxus | cds-NP_219497.4_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |