LSB3 (YFR024C-A)


Gene profile

Gene name: LSB3
Reference locus (S288C): YFR024C-A
Gene biotype: protein_coding

Description: Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; protein abundance increases in response to DNA replication stress; LSB3 has a paralog, YSC84, that arose from the whole genome duplication

Top 10 interactors (score): YSC84 (0.999); SLA1 (0.991); LAS17 (0.984); CUE5 (0.932); ERG12 (0.918); BZZ1 (0.87); BBC1 (0.865); BSP1 (0.852); MYO5 (0.845); GTS1 (0.816); ABP1 (0.812); HUA1 (0.772); AIM21 (0.758); MYO3 (0.749); BOI2 (0.738); END3 (0.737); YPR089W (0.716); RVS161 (0.712); JIP4 (0.699); TPH3 (0.69)

Homologues (species, bitscore): SH3YL1 (Homo sapiens, 248.8); Sh3yl1 (Mus musculus, 245.7); sh3yl1 (Danio rerio, 252.3); sh3yl1 (Xenopus tropicalis, 222.6); Drk (Drosophila melanogaster, 65.5); itsn-1 (Caenorhabditis elegans, 67.4); AT3G43230 (Arabidopsis thaliana, 165.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005300.1:192165-193638:- gene-YFR024C-A_AKU4011 rna-NM_001180865.3_AKU4011 cds-NP_219497.4_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000071.1:67026-68499:+ gene-YFR024C-A_BG1 rna-NM_001180865.3_BG1 cds-NP_219497.4_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005508.1:195005-196478:- gene-YFR024C-A_Bruggeman rna-NM_001180865.3_Bruggeman cds-NP_219497.4_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005524.1:197534-199007:- gene-YFR024C-A_CAT1 rna-NM_001180865.3_CAT1 cds-NP_219497.4_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005364.1:193656-195129:- gene-YFR024C-A_CBS1585 rna-NM_001180865.3_CBS1585 cds-NP_219497.4_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005348.1:166886-168359:- gene-YFR024C-A_CBS436 rna-NM_001180865.3_CBS436 cds-NP_219497.4_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005332.1:192737-194210:- gene-YFR024C-A_CBS6412 rna-NM_001180865.3_CBS6412 cds-NP_219497.4_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005316.1:195392-196865:- gene-YFR024C-A_CBS6413 rna-NM_001180865.3_CBS6413 cds-NP_219497.4_CBS6413 99.4 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001527.1:198001-199474:- gene-YFR024C-A_CENPK1137D rna-NM_001180865.3_CENPK1137D cds-NP_219497.4_CENPK1137D 99.4 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005476.1:191273-192746:- gene-YFR024C-A_EthanolRed rna-NM_001180865.3_EthanolRed cds-NP_219497.4_EthanolRed 99.1 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005540.1:192923-194396:- gene-YFR024C-A_FaliES1 rna-NM_001180865.3_FaliES1 cds-NP_219497.4_FaliES1 99.1 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000452.1:39679-41152:- gene-YFR024C-A_JAY291 rna-NM_001180865.3_JAY291 cds-NP_219497.4_JAY291 99.8 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005412.1:195484-196957:- gene-YFR024C-A_MUCL30387 rna-NM_001180865.3_MUCL30387 cds-NP_219497.4_MUCL30387 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005444.1:191741-193214:- gene-YFR024C-A_MUCL30388 rna-NM_001180865.3_MUCL30388 cds-NP_219497.4_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005284.1:191575-193048:- gene-YFR024C-A_MUCL39482 rna-NM_001180865.3_MUCL39482 cds-NP_219497.4_MUCL39482 99.4 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005428.1:190883-192356:- gene-YFR024C-A_MUCL42920 rna-NM_001180865.3_MUCL42920 cds-NP_219497.4_MUCL42920 99.4 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011815.1:201959-203432:- gene-YFR024C-A_NCIM3186 rna-NM_001180865.3_NCIM3186 cds-NP_219497.4_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005268.1:192457-193930:- gene-YFR024C-A_NCYC1407 rna-NM_001180865.3_NCYC1407 cds-NP_219497.4_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994145.1:234893-236366:- gene-YFR024C-A_PE2H3 rna-NM_001180865.3_PE2H3 cds-NP_219497.4_PE2H3 99.8 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999877.1:234441-235914:- gene-YFR024C-A_PE2H4 rna-NM_001180865.3_PE2H4 cds-NP_219497.4_PE2H4 99.8 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001138.5:201960-203433:- gene-YFR024C-A_S288C rna-NM_001180865.3_S288C cds-NP_219497.4_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000011.1:121003-122476:+ gene-YFR024C-A_SA1 rna-NM_001180865.3_SA1 cds-NP_219497.4_SA1 99.4 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005492.1:192080-193553:- gene-YFR024C-A_ThermosaccDry rna-NM_001180865.3_ThermosaccDry cds-NP_219497.4_ThermosaccDry 99.1 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005460.1:208124-209597:- gene-YFR024C-A_VR1 rna-NM_001180865.3_VR1 cds-NP_219497.4_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000013.1:122553-124026:- gene-YFR024C-A_ZTW1 rna-NM_001180865.3_ZTW1 cds-NP_219497.4_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047492.1:216037-217513:- gene-YFR024C-A_Sparadoxus rna-NM_001180865.3_Sparadoxus cds-NP_219497.4_Sparadoxus 92.1 100.0 Verified 1 1 1 False True False False False

Additional files