LRS4 (YDR439W)


Gene profile

Gene name: LRS4
Reference locus (S288C): YDR439W
Gene biotype: protein_coding

Description: Monopolin complex subunit LRS4; Nucleolar protein that forms a complex with Csm1p; and then Mam1p at kinetochores during meiosis I to mediate accurate homolog segregation; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation

Top 10 interactors (score): CSM1 (0.999); HRR25 (0.993); MAM1 (0.991); SRC1 (0.984); NUR1 (0.977); TOF2 (0.975); CDC14 (0.937); NET1 (0.887); FOB1 (0.884); SIR2 (0.823); BRN1 (0.75); SIR4 (0.723); HEH2 (0.685); ESC1 (0.679); SMC2 (0.635); SPO13 (0.617); CDC5 (0.608); ULP2 (0.597); CDC7 (0.571); DSF1 (0.571)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1279948-1280991:+ gene-YDR439W_AKU4011 rna-NM_001180747.1_AKU4011 cds-NP_010727.1_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000039.1:158285-159328:+ gene-YDR439W_BG1 rna-NM_001180747.1_BG1 cds-NP_010727.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1310331-1311374:+ gene-YDR439W_Bruggeman rna-NM_001180747.1_Bruggeman cds-NP_010727.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1288522-1289565:+ gene-YDR439W_CAT1 rna-NM_001180747.1_CAT1 cds-NP_010727.1_CAT1 99.9 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1274255-1275298:+ gene-YDR439W_CBS1585 rna-NM_001180747.1_CBS1585 cds-NP_010727.1_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1293606-1294649:+ gene-YDR439W_CBS436 rna-NM_001180747.1_CBS436 cds-NP_010727.1_CBS436 99.9 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1269893-1270936:+ gene-YDR439W_CBS6412 rna-NM_001180747.1_CBS6412 cds-NP_010727.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1292407-1293450:+ gene-YDR439W_CBS6413 rna-NM_001180747.1_CBS6413 cds-NP_010727.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1338354-1339397:+ gene-YDR439W_CENPK1137D rna-NM_001180747.1_CENPK1137D cds-NP_010727.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1283318-1284361:+ gene-YDR439W_EthanolRed rna-NM_001180747.1_EthanolRed cds-NP_010727.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1286869-1287912:+ gene-YDR439W_FaliES1 rna-NM_001180747.1_FaliES1 cds-NP_010727.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000263.1:31089-32132:+ gene-YDR439W_JAY291 rna-NM_001180747.1_JAY291 cds-NP_010727.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1293974-1295017:+ gene-YDR439W_MUCL30387 rna-NM_001180747.1_MUCL30387 cds-NP_010727.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1275907-1276950:+ gene-YDR439W_MUCL30388 rna-NM_001180747.1_MUCL30388 cds-NP_010727.1_MUCL30388 99.7 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1265746-1266789:+ gene-YDR439W_MUCL39482 rna-NM_001180747.1_MUCL39482 cds-NP_010727.1_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1208166-1209209:+ gene-YDR439W_MUCL42920 rna-NM_001180747.1_MUCL42920 cds-NP_010727.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1339599-1340642:+ gene-YDR439W_NCIM3186 rna-NM_001180747.1_NCIM3186 cds-NP_010727.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1279511-1280554:+ gene-YDR439W_NCYC1407 rna-NM_001180747.1_NCYC1407 cds-NP_010727.1_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1290332-1291375:+ gene-YDR439W_PE2H3 rna-NM_001180747.1_PE2H3 cds-NP_010727.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1295900-1296943:+ gene-YDR439W_PE2H4 rna-NM_001180747.1_PE2H4 cds-NP_010727.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1339676-1340719:+ gene-YDR439W_S288C rna-NM_001180747.1_S288C cds-NP_010727.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000082.1:16497-17540:- gene-YDR439W_SA1 rna-NM_001180747.1_SA1 cds-NP_010727.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1291093-1292136:+ gene-YDR439W_ThermosaccDry rna-NM_001180747.1_ThermosaccDry cds-NP_010727.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1306313-1307356:+ gene-YDR439W_VR1 rna-NM_001180747.1_VR1 cds-NP_010727.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:333729-334772:+ gene-YDR439W_ZTW1 rna-NM_001180747.1_ZTW1 cds-NP_010727.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1287475-1288518:+ gene-YDR439W_Sparadoxus rna-NM_001180747.1_Sparadoxus cds-NP_010727.1_Sparadoxus 86.0 99.4 Verified 1 1 1 False True False False False

Additional files