LRP1 (YHR081W)


Gene profile

Gene name: LRP1
Reference locus (S288C): YHR081W
Gene biotype: protein_coding

Description: Nuclear exosome-associated nucleic acid binding protein; involved in RNA processing, surveillance, degradation, tethering, and export; forms a stable heterodimer with Rrp6p and regulates its exonucleolytic activity; rapidly degraded by the proteasome in the absence of Rrp6p; homolog of mammalian nuclear matrix protein C1D involved in regulation of DNA repair and recombination

Top 10 interactors (score): RRP45 (0.999); MTR4 (0.999); DIS3 (0.999); RRP6 (0.999); RRP43 (0.999); CSL4 (0.999); RRP40 (0.999); RRP4 (0.999); RRP46 (0.999); MPP6 (0.999); RRP42 (0.998); MTR3 (0.997); SKI6 (0.995); SAS10 (0.99); IMP4 (0.94); UTP18 (0.936); UTP6 (0.907); RRT14 (0.906); NOP56 (0.895); RNH70 (0.892)

Homologues (species, bitscore): c1d (Danio rerio, 52.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005302.1:253949-254503:+ gene-YHR081W_AKU4011 rna-NM_001179211.1_AKU4011 cds-NP_011949.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000053.1:174296-174850:+ gene-YHR081W_BG1 rna-NM_001179211.1_BG1 cds-NP_011949.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005510.1:261776-262330:+ gene-YHR081W_Bruggeman rna-NM_001179211.1_Bruggeman cds-NP_011949.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005526.1:256919-257473:+ gene-YHR081W_CAT1 rna-NM_001179211.1_CAT1 cds-NP_011949.1_CAT1 99.8 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005366.1:252991-253545:+ gene-YHR081W_CBS1585 rna-NM_001179211.1_CBS1585 cds-NP_011949.1_CBS1585 99.6 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005350.1:250852-251406:+ gene-YHR081W_CBS436 rna-NM_001179211.1_CBS436 cds-NP_011949.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005334.1:256338-256892:+ gene-YHR081W_CBS6412 rna-NM_001179211.1_CBS6412 cds-NP_011949.1_CBS6412 99.4 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005318.1:254030-254584:+ gene-YHR081W_CBS6413 rna-NM_001179211.1_CBS6413 cds-NP_011949.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001529.1:260709-261263:+ gene-YHR081W_CENPK1137D rna-NM_001179211.1_CENPK1137D cds-NP_011949.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005478.1:313556-314110:+ gene-YHR081W_EthanolRed rna-NM_001179211.1_EthanolRed cds-NP_011949.1_EthanolRed 99.8 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005542.1:254360-254914:+ gene-YHR081W_FaliES1 rna-NM_001179211.1_FaliES1 cds-NP_011949.1_FaliES1 99.8 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000394.1:37085-37639:+ gene-YHR081W_JAY291 rna-NM_001179211.1_JAY291 cds-NP_011949.1_JAY291 99.4 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005414.1:261296-261850:+ gene-YHR081W_MUCL30387 rna-NM_001179211.1_MUCL30387 cds-NP_011949.1_MUCL30387 99.6 100.0 Unannotated 1 1 0 False False False False True
MUCL30388 GCA_001738495.1 Bread Europe CM005446.1:261160-261714:+ gene-YHR081W_MUCL30388 rna-NM_001179211.1_MUCL30388 cds-NP_011949.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005286.1:253314-253868:+ gene-YHR081W_MUCL39482 rna-NM_001179211.1_MUCL39482 cds-NP_011949.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005430.1:260059-260613:+ gene-YHR081W_MUCL42920 rna-NM_001179211.1_MUCL42920 cds-NP_011949.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011817.1:267420-267974:+ gene-YHR081W_NCIM3186 rna-NM_001179211.1_NCIM3186 cds-NP_011949.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005270.1:255778-256332:+ gene-YHR081W_NCYC1407 rna-NM_001179211.1_NCYC1407 cds-NP_011949.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994147.1:255449-256003:+ gene-YHR081W_PE2H3 rna-NM_001179211.1_PE2H3 cds-NP_011949.1_PE2H3 99.4 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999879.1:262896-263450:+ gene-YHR081W_PE2H4 rna-NM_001179211.1_PE2H4 cds-NP_011949.1_PE2H4 99.4 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001140.6:267538-268092:+ gene-YHR081W_S288C rna-NM_001179211.1_S288C cds-NP_011949.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000014.1:90896-91450:- gene-YHR081W_SA1 rna-NM_001179211.1_SA1 cds-NP_011949.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005494.1:255451-256005:+ gene-YHR081W_ThermosaccDry rna-NM_001179211.1_ThermosaccDry cds-NP_011949.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005462.1:263324-263878:+ gene-YHR081W_VR1 rna-NM_001179211.1_VR1 cds-NP_011949.1_VR1 99.4 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000017.1:247004-247558:+ gene-YHR081W_ZTW1 rna-NM_001179211.1_ZTW1 cds-NP_011949.1_ZTW1 99.8 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047494.1:252771-253328:+ gene-YHR081W_Sparadoxus rna-NM_001179211.1_Sparadoxus cds-NP_011949.1_Sparadoxus 86.4 99.8 Verified 1 1 1 False True False False False

Additional files