Gene name: LRG1
Reference locus (S288C): YDL240W
Gene biotype: protein_coding
Description: Rho-GTPase-activating protein LRG1; GTPase-activating protein (GAP); contains Rho1p-specific GAP activity, interacting with activated forms of Rho1p; functions along with Sac7p as a negative regulator of the Pkc1p-mediated cell wall integrity signaling pathway; negative regulator of cell wall 1,3-beta-glucan biosynthesis; required for efficient cell fusion; contains a RhoGAP domain and three Lin-11-Isl1-Mec-3 (LIM) domains
Top 10 interactors (score): RHO1 (0.999); ROM2 (0.974); CDC42 (0.973); HOF1 (0.937); SAC7 (0.936); PKC1 (0.935); NTE1 (0.934); RGA1 (0.933); GIS1 (0.913); TUS1 (0.912); TRS120 (0.908); SPF1 (0.908); RPH1 (0.908); CHC1 (0.902); SNF2 (0.902); STH1 (0.902); ACT1 (0.899); CRM1 (0.897); SPT6 (0.896); UFD2 (0.896)
Homologues (species, bitscore): TGFB1I1 (Homo sapiens, 89.4); Tgfb1i1 (Mus musculus, 88.2); ARHGAP6 (Danio rerio, 91.7); arhgap6 (Xenopus tropicalis, 84.7); CG30178 (Drosophila melanogaster, 89.0); rga-6 (Caenorhabditis elegans, 85.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:6002-9055:+ | gene-YDL240W_AKU4011 | rna-NM_001180300.2_AKU4011 | cds-NP_010041.2_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000077.1:57471-60524:- | gene-YDL240W_BG1 | rna-NM_001180300.2_BG1 | cds-NP_010041.2_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:21642-24695:+ | gene-YDL240W_Bruggeman | rna-NM_001180300.2_Bruggeman | cds-NP_010041.2_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:24568-27621:+ | gene-YDL240W_CAT1 | rna-NM_001180300.2_CAT1 | cds-NP_010041.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:5374-8427:+ | gene-YDL240W_CBS1585 | rna-NM_001180300.2_CBS1585 | cds-NP_010041.2_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:22069-25122:+ | gene-YDL240W_CBS436 | rna-NM_001180300.2_CBS436 | cds-NP_010041.2_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:5823-8876:+ | gene-YDL240W_CBS6412 | rna-NM_001180300.2_CBS6412 | cds-NP_010041.2_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:22762-25815:+ | gene-YDL240W_CBS6413 | rna-NM_001180300.2_CBS6413 | cds-NP_010041.2_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:21791-24844:+ | gene-YDL240W_CENPK1137D | rna-NM_001180300.2_CENPK1137D | cds-NP_010041.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:19527-22580:+ | gene-YDL240W_EthanolRed | rna-NM_001180300.2_EthanolRed | cds-NP_010041.2_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:22829-25882:+ | gene-YDL240W_FaliES1 | rna-NM_001180300.2_FaliES1 | cds-NP_010041.2_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000011.1:18649-21702:- | gene-YDL240W_JAY291 | rna-NM_001180300.2_JAY291 | cds-NP_010041.2_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:20942-23995:+ | gene-YDL240W_MUCL30387 | rna-NM_001180300.2_MUCL30387 | cds-NP_010041.2_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:10509-13562:+ | gene-YDL240W_MUCL30388 | rna-NM_001180300.2_MUCL30388 | cds-NP_010041.2_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:5970-9023:+ | gene-YDL240W_MUCL39482 | rna-NM_001180300.2_MUCL39482 | cds-NP_010041.2_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:22081-25134:+ | gene-YDL240W_MUCL42920 | rna-NM_001180300.2_MUCL42920 | cds-NP_010041.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:22746-25799:+ | gene-YDL240W_NCIM3186 | rna-NM_001180300.2_NCIM3186 | cds-NP_010041.2_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:5927-8980:+ | gene-YDL240W_NCYC1407 | rna-NM_001180300.2_NCYC1407 | cds-NP_010041.2_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:13148-16201:+ | gene-YDL240W_PE2H3 | rna-NM_001180300.2_PE2H3 | cds-NP_010041.2_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:13148-16201:+ | gene-YDL240W_PE2H4 | rna-NM_001180300.2_PE2H4 | cds-NP_010041.2_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:22823-25876:+ | gene-YDL240W_S288C | rna-NM_001180300.2_S288C | cds-NP_010041.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000107.1:18429-21482:- | gene-YDL240W_SA1 | rna-NM_001180300.2_SA1 | cds-NP_010041.2_SA1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:22957-26010:+ | gene-YDL240W_ThermosaccDry | rna-NM_001180300.2_ThermosaccDry | cds-NP_010041.2_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:22882-25935:+ | gene-YDL240W_VR1 | rna-NM_001180300.2_VR1 | cds-NP_010041.2_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:22018-25071:+ | gene-YDL240W_ZTW1 | rna-NM_001180300.2_ZTW1 | cds-NP_010041.2_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:25308-28361:+ | gene-YDL240W_Sparadoxus | rna-NM_001180300.2_Sparadoxus | cds-NP_010041.2_Sparadoxus | 90.7 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |