LIF1 (YGL090W)


Gene profile

Gene name: LIF1
Reference locus (S288C): YGL090W
Gene biotype: protein_coding

Description: Ligase-interacting factor 1; Component of the DNA ligase IV complex; this complex mediates nonhomologous end joining in DNA double-strand break repair; physically interacts with Dnl4p and Nej1p; homologous to mammalian XRCC4 protein

Top 10 interactors (score): NEJ1 (0.999); DNL4 (0.999); YKU70 (0.973); YKU80 (0.955); POL4 (0.95); SPP382 (0.81); XRS2 (0.788); MRE11 (0.786); RAD51 (0.785); CDC9 (0.785); RAD52 (0.762); EXO1 (0.748); DNA2 (0.744); RAD27 (0.71); SAE2 (0.691); MEC1 (0.684); RAD55 (0.676); SGS1 (0.67); RAD57 (0.616); RAD59 (0.612)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:346324-347589:+ gene-YGL090W_AKU4011 rna-NM_001180955.1_AKU4011 cds-NP_011425.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:57828-59093:- gene-YGL090W_BG1 rna-NM_001180955.1_BG1 cds-NP_011425.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:348816-350081:+ gene-YGL090W_Bruggeman rna-NM_001180955.1_Bruggeman cds-NP_011425.1_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:345709-346974:+ gene-YGL090W_CAT1 rna-NM_001180955.1_CAT1 cds-NP_011425.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:349649-350914:+ gene-YGL090W_CBS1585 rna-NM_001180955.1_CBS1585 cds-NP_011425.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:343933-345198:+ gene-YGL090W_CBS436 rna-NM_001180955.1_CBS436 cds-NP_011425.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:334030-335295:+ gene-YGL090W_CBS6412 rna-NM_001180955.1_CBS6412 cds-NP_011425.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:343955-345220:+ gene-YGL090W_CBS6413 rna-NM_001180955.1_CBS6413 cds-NP_011425.1_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:343506-344771:+ gene-YGL090W_CENPK1137D rna-NM_001180955.1_CENPK1137D cds-NP_011425.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:335409-336674:+ gene-YGL090W_EthanolRed rna-NM_001180955.1_EthanolRed cds-NP_011425.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:337970-339235:+ gene-YGL090W_FaliES1 rna-NM_001180955.1_FaliES1 cds-NP_011425.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000369.1:23580-24845:+ gene-YGL090W_JAY291 rna-NM_001180955.1_JAY291 cds-NP_011425.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:345793-347058:+ gene-YGL090W_MUCL30387 rna-NM_001180955.1_MUCL30387 cds-NP_011425.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:348779-350044:+ gene-YGL090W_MUCL30388 rna-NM_001180955.1_MUCL30388 cds-NP_011425.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:346177-347442:+ gene-YGL090W_MUCL39482 rna-NM_001180955.1_MUCL39482 cds-NP_011425.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:350704-351969:+ gene-YGL090W_MUCL42920 rna-NM_001180955.1_MUCL42920 cds-NP_011425.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:343319-344584:+ gene-YGL090W_NCIM3186 rna-NM_001180955.1_NCIM3186 cds-NP_011425.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:337712-338977:+ gene-YGL090W_NCYC1407 rna-NM_001180955.1_NCYC1407 cds-NP_011425.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:339346-340611:+ gene-YGL090W_PE2H3 rna-NM_001180955.1_PE2H3 cds-NP_011425.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:344343-345608:+ gene-YGL090W_PE2H4 rna-NM_001180955.1_PE2H4 cds-NP_011425.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:343319-344584:+ gene-YGL090W_S288C rna-NM_001180955.1_S288C cds-NP_011425.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000089.1:20700-21965:+ gene-YGL090W_SA1 rna-NM_001180955.1_SA1 cds-NP_011425.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:338223-339488:+ gene-YGL090W_ThermosaccDry rna-NM_001180955.1_ThermosaccDry cds-NP_011425.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:448084-449349:+ gene-YGL090W_VR1 rna-NM_001180955.1_VR1 cds-NP_011425.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:335577-336842:+ gene-YGL090W_ZTW1 rna-NM_001180955.1_ZTW1 cds-NP_011425.1_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:341264-342504:+ gene-YGL090W_Sparadoxus rna-NM_001180955.1_Sparadoxus cds-NP_011425.1_Sparadoxus 83.7 98.0 Verified 1 1 0 False False False True False

Additional files