Gene name: LIA1
Reference locus (S288C): YJR070C
Gene biotype: protein_coding
Description: Deoxyhypusine hydroxylase; HEAT-repeat containing metalloenzyme that catalyzes hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): DYS1 (0.999); HYP2 (0.999); ANB1 (0.995); RRB1 (0.991); HAS1 (0.991); NOG1 (0.988); BRX1 (0.984); MRT4 (0.983); URA7 (0.978); NOP7 (0.978); PWP1 (0.971); NIP7 (0.97); SMT3 (0.963); URH1 (0.962); PNO1 (0.957); YTM1 (0.956); ENP1 (0.956); RPF2 (0.953); GUA1 (0.933); NUG1 (0.928)
Homologues (species, bitscore): DOHH (Homo sapiens, 249.6); Dohh (Mus musculus, 256.1); dohh (Danio rerio, 276.6); DOHH (Xenopus tropicalis, 211.8); nero (Drosophila melanogaster, 256.9); dohh-1 (Caenorhabditis elegans, 257.7); AT3G58180 (Arabidopsis thaliana, 196.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:541147-542124:- | gene-YJR070C_AKU4011 | rna-NM_001181728.1_AKU4011 | cds-NP_012604.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:65495-66472:+ | gene-YJR070C_BG1 | rna-NM_001181728.1_BG1 | cds-NP_012604.1_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:554663-555640:- | gene-YJR070C_Bruggeman | rna-NM_001181728.1_Bruggeman | cds-NP_012604.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:558969-559946:- | gene-YJR070C_CAT1 | rna-NM_001181728.1_CAT1 | cds-NP_012604.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:553211-554188:- | gene-YJR070C_CBS1585 | rna-NM_001181728.1_CBS1585 | cds-NP_012604.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:571283-572260:- | gene-YJR070C_CBS436 | rna-NM_001181728.1_CBS436 | cds-NP_012604.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:540360-541337:- | gene-YJR070C_CBS6412 | rna-NM_001181728.1_CBS6412 | cds-NP_012604.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:542658-543635:- | gene-YJR070C_CBS6413 | rna-NM_001181728.1_CBS6413 | cds-NP_012604.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:551982-552959:- | gene-YJR070C_CENPK1137D | rna-NM_001181728.1_CENPK1137D | cds-NP_012604.1_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:545541-546518:- | gene-YJR070C_EthanolRed | rna-NM_001181728.1_EthanolRed | cds-NP_012604.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:557007-557984:- | gene-YJR070C_FaliES1 | rna-NM_001181728.1_FaliES1 | cds-NP_012604.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000054.1:131402-132379:+ | gene-YJR070C_JAY291 | rna-NM_001181728.1_JAY291 | cds-NP_012604.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:555193-556170:- | gene-YJR070C_MUCL30387 | rna-NM_001181728.1_MUCL30387 | cds-NP_012604.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:552486-553463:- | gene-YJR070C_MUCL30388 | rna-NM_001181728.1_MUCL30388 | cds-NP_012604.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:546673-547650:- | gene-YJR070C_MUCL39482 | rna-NM_001181728.1_MUCL39482 | cds-NP_012604.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:550917-551894:- | gene-YJR070C_MUCL42920 | rna-NM_001181728.1_MUCL42920 | cds-NP_012604.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:569600-570577:- | gene-YJR070C_NCIM3186 | rna-NM_001181728.1_NCIM3186 | cds-NP_012604.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:544237-545214:- | gene-YJR070C_NCYC1407 | rna-NM_001181728.1_NCYC1407 | cds-NP_012604.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:562128-563105:- | gene-YJR070C_PE2H3 | rna-NM_001181728.1_PE2H3 | cds-NP_012604.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:555824-556801:- | gene-YJR070C_PE2H4 | rna-NM_001181728.1_PE2H4 | cds-NP_012604.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:569621-570598:- | gene-YJR070C_S288C | rna-NM_001181728.1_S288C | cds-NP_012604.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000038.1:28200-29177:- | gene-YJR070C_SA1 | rna-NM_001181728.1_SA1 | cds-NP_012604.1_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:550939-551916:- | gene-YJR070C_ThermosaccDry | rna-NM_001181728.1_ThermosaccDry | cds-NP_012604.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:553116-554093:- | gene-YJR070C_VR1 | rna-NM_001181728.1_VR1 | cds-NP_012604.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:530340-531317:- | gene-YJR070C_ZTW1 | rna-NM_001181728.1_ZTW1 | cds-NP_012604.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:563706-564683:- | gene-YJR070C_Sparadoxus | rna-NM_001181728.1_Sparadoxus | cds-NP_012604.1_Sparadoxus | 93.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |