Gene name: LHS1
Reference locus (S288C): YKL073W
Gene biotype: protein_coding
Description: Heat shock protein 70 homolog LHS1; Molecular chaperone of the endoplasmic reticulum lumen; involved in polypeptide translocation and folding; nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p; regulated by the unfolded protein response pathway
Top 10 interactors (score): KAR2 (0.999); PDI1 (0.997); SIL1 (0.997); SEC63 (0.996); EUG1 (0.993); SCJ1 (0.991); SEC61 (0.988); CNE1 (0.988); WBP1 (0.972); ZUO1 (0.961); ERO1 (0.952); HUT1 (0.939); HSP82 (0.933); SSH1 (0.928); ERV29 (0.924); IRE1 (0.923); YOS9 (0.921); ERD2 (0.92); JEM1 (0.914); SEC13 (0.914)
Homologues (species, bitscore): HYOU1 (Homo sapiens, 217.6); Hyou1 (Mus musculus, 213.0); hyou1 (Danio rerio, 215.3); hyou1 (Xenopus tropicalis, 205.7); CG2918 (Drosophila melanogaster, 186.8); T14G8.3 (Caenorhabditis elegans, 162.2); AT4G16660 (Arabidopsis thaliana, 160.2)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:282988-285633:+ | gene-YKL073W_AKU4011 | rna-NM_001179639.1_AKU4011 | cds-NP_012850.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:359109-361754:- | gene-YKL073W_BG1 | rna-NM_001179639.1_BG1 | cds-NP_012850.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:301153-303798:+ | gene-YKL073W_Bruggeman | rna-NM_001179639.1_Bruggeman | cds-NP_012850.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:295958-298603:+ | gene-YKL073W_CAT1 | rna-NM_001179639.1_CAT1 | cds-NP_012850.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:295229-297874:+ | gene-YKL073W_CBS1585 | rna-NM_001179639.1_CBS1585 | cds-NP_012850.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:293822-296467:+ | gene-YKL073W_CBS436 | rna-NM_001179639.1_CBS436 | cds-NP_012850.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:279856-282501:+ | gene-YKL073W_CBS6412 | rna-NM_001179639.1_CBS6412 | cds-NP_012850.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:295683-298328:+ | gene-YKL073W_CBS6413 | rna-NM_001179639.1_CBS6413 | cds-NP_012850.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:296073-298718:+ | gene-YKL073W_CENPK1137D | rna-NM_001179639.1_CENPK1137D | cds-NP_012850.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:293679-296324:+ | gene-YKL073W_EthanolRed | rna-NM_001179639.1_EthanolRed | cds-NP_012850.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:294491-297136:+ | gene-YKL073W_FaliES1 | rna-NM_001179639.1_FaliES1 | cds-NP_012850.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000357.1:116820-119465:+ | gene-YKL073W_JAY291 | rna-NM_001179639.1_JAY291 | cds-NP_012850.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:302954-305599:+ | gene-YKL073W_MUCL30387 | rna-NM_001179639.1_MUCL30387 | cds-NP_012850.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:297349-299994:+ | gene-YKL073W_MUCL30388 | rna-NM_001179639.1_MUCL30388 | cds-NP_012850.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:295014-297659:+ | gene-YKL073W_MUCL39482 | rna-NM_001179639.1_MUCL39482 | cds-NP_012850.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:299643-302288:+ | gene-YKL073W_MUCL42920 | rna-NM_001179639.1_MUCL42920 | cds-NP_012850.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:296419-299064:+ | gene-YKL073W_NCIM3186 | rna-NM_001179639.1_NCIM3186 | cds-NP_012850.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:295209-297854:+ | gene-YKL073W_NCYC1407 | rna-NM_001179639.1_NCYC1407 | cds-NP_012850.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:302298-304943:+ | gene-YKL073W_PE2H3 | rna-NM_001179639.1_PE2H3 | cds-NP_012850.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:298585-301230:+ | gene-YKL073W_PE2H4 | rna-NM_001179639.1_PE2H4 | cds-NP_012850.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:296430-299075:+ | gene-YKL073W_S288C | rna-NM_001179639.1_S288C | cds-NP_012850.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000008.1:212558-215203:+ | gene-YKL073W_SA1 | rna-NM_001179639.1_SA1 | cds-NP_012850.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:295200-297845:+ | gene-YKL073W_ThermosaccDry | rna-NM_001179639.1_ThermosaccDry | cds-NP_012850.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:294558-297203:+ | gene-YKL073W_VR1 | rna-NM_001179639.1_VR1 | cds-NP_012850.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:293759-296404:+ | gene-YKL073W_ZTW1 | rna-NM_001179639.1_ZTW1 | cds-NP_012850.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:310698-313343:+ | gene-YKL073W_Sparadoxus | rna-NM_001179639.1_Sparadoxus | cds-NP_012850.1_Sparadoxus | 89.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |