Gene name: LEU5
Reference locus (S288C): YHR002W
Gene biotype: protein_coding
Description: Mitochondrial carrier protein; involved in the accumulation of CoA in the mitochondrial matrix; homolog of human Graves disease protein SLC25A16, which complements yeast null mutant; does not encode an isozyme of Leu4p, as first hypothesized
Top 10 interactors (score): LEU4 (0.918); FLX1 (0.793); ANT1 (0.768); ARG2 (0.751); LEU9 (0.711); NAM2 (0.702); YMR226C (0.671); QCR10 (0.648); DBP8 (0.594); YPR003C (0.591); SLY41 (0.579); YJL193W (0.572); YMD8 (0.56); LEU3 (0.551); EAF6 (0.532); ERD2 (0.532); YKL071W (0.53); PAT1 (0.53); APL5 (0.515); YHI9 (0.513)
Homologues (species, bitscore): SLC25A16 (Homo sapiens, 209.1); Slc25a16 (Mus musculus, 211.1); slc25a16 (Danio rerio, 198.7); slc25a16 (Xenopus tropicalis, 189.5); att-ORFA (Drosophila melanogaster, 174.1); F43G9.3 (Caenorhabditis elegans, 147.5); AT1G14560 (Arabidopsis thaliana, 169.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:97425-98498:+ | gene-YHR002W_AKU4011 | rna-NM_001179132.1_AKU4011 | cds-NP_011865.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000053.1:17141-18214:+ | gene-YHR002W_BG1 | rna-NM_001179132.1_BG1 | cds-NP_011865.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:104283-105356:+ | gene-YHR002W_Bruggeman | rna-NM_001179132.1_Bruggeman | cds-NP_011865.1_Bruggeman | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:98267-99340:+ | gene-YHR002W_CAT1 | rna-NM_001179132.1_CAT1 | cds-NP_011865.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:98012-99085:+ | gene-YHR002W_CBS1585 | rna-NM_001179132.1_CBS1585 | cds-NP_011865.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:90510-91583:+ | gene-YHR002W_CBS436 | rna-NM_001179132.1_CBS436 | cds-NP_011865.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:97611-98684:+ | gene-YHR002W_CBS6412 | rna-NM_001179132.1_CBS6412 | cds-NP_011865.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:97337-98410:+ | gene-YHR002W_CBS6413 | rna-NM_001179132.1_CBS6413 | cds-NP_011865.1_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:101970-103043:+ | gene-YHR002W_CENPK1137D | rna-NM_001179132.1_CENPK1137D | cds-NP_011865.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:97421-98494:+ | gene-YHR002W_EthanolRed | rna-NM_001179132.1_EthanolRed | cds-NP_011865.1_EthanolRed | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:97950-99023:+ | gene-YHR002W_FaliES1 | rna-NM_001179132.1_FaliES1 | cds-NP_011865.1_FaliES1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000064.1:22937-24010:- | gene-YHR002W_JAY291 | rna-NM_001179132.1_JAY291 | cds-NP_011865.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:101023-102096:+ | gene-YHR002W_MUCL30387 | rna-NM_001179132.1_MUCL30387 | cds-NP_011865.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:102234-103307:+ | gene-YHR002W_MUCL30388 | rna-NM_001179132.1_MUCL30388 | cds-NP_011865.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:97038-98111:+ | gene-YHR002W_MUCL39482 | rna-NM_001179132.1_MUCL39482 | cds-NP_011865.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:100943-102016:+ | gene-YHR002W_MUCL42920 | rna-NM_001179132.1_MUCL42920 | cds-NP_011865.1_MUCL42920 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:108694-109767:+ | gene-YHR002W_NCIM3186 | rna-NM_001179132.1_NCIM3186 | cds-NP_011865.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:96454-97527:+ | gene-YHR002W_NCYC1407 | rna-NM_001179132.1_NCYC1407 | cds-NP_011865.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:98660-99733:+ | gene-YHR002W_PE2H3 | rna-NM_001179132.1_PE2H3 | cds-NP_011865.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:106101-107174:+ | gene-YHR002W_PE2H4 | rna-NM_001179132.1_PE2H4 | cds-NP_011865.1_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:108812-109885:+ | gene-YHR002W_S288C | rna-NM_001179132.1_S288C | cds-NP_011865.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000075.1:36657-37730:- | gene-YHR002W_SA1 | rna-NM_001179132.1_SA1 | cds-NP_011865.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:99040-100113:+ | gene-YHR002W_ThermosaccDry | rna-NM_001179132.1_ThermosaccDry | cds-NP_011865.1_ThermosaccDry | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:104587-105660:+ | gene-YHR002W_VR1 | rna-NM_001179132.1_VR1 | cds-NP_011865.1_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:90205-91278:+ | gene-YHR002W_ZTW1 | rna-NM_001179132.1_ZTW1 | cds-NP_011865.1_ZTW1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:96815-97888:+ | gene-YHR002W_Sparadoxus | rna-NM_001179132.1_Sparadoxus | cds-NP_011865.1_Sparadoxus | 93.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |