Gene name: LEO1
Reference locus (S288C): YOR123C
Gene biotype: protein_coding
Description: RNA polymerase-associated protein LEO1; Component of the Paf1 complex; which associates with RNA polymerase II and is involved in histone methylation; plays a role in regulating Ty1 transposition; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay
Top 10 interactors (score): SPT5 (0.999); CTR9 (0.999); RTF1 (0.999); PAF1 (0.999); POB3 (0.999); SKI8 (0.999); CDC73 (0.999); SPT16 (0.998); RPO21 (0.996); SPN1 (0.995); RPB3 (0.993); SPT4 (0.992); DST1 (0.985); SPT6 (0.982); RPB7 (0.975); BRE1 (0.964); GLE2 (0.962); RPB9 (0.939); SPT2 (0.935); BUR2 (0.928)
Homologues (species, bitscore): LEO1 (Homo sapiens, 109.8); Leo1 (Mus musculus, 109.4); leo1 (Danio rerio, 112.1); leo1 (Xenopus tropicalis, 104.8); Atu (Drosophila melanogaster, 81.6); B0035.11 (Caenorhabditis elegans, 89.0); VIP4 (Arabidopsis thaliana, 84.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:537240-538634:- | gene-YOR123C_AKU4011 | rna-NM_001183542.1_AKU4011 | cds-NP_014766.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000171.1:40637-42031:+ | gene-YOR123C_BG1 | rna-NM_001183542.1_BG1 | cds-NP_014766.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:540788-542182:- | gene-YOR123C_Bruggeman | rna-NM_001183542.1_Bruggeman | cds-NP_014766.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:540793-542187:- | gene-YOR123C_CAT1 | rna-NM_001183542.1_CAT1 | cds-NP_014766.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:532802-534196:- | gene-YOR123C_CBS1585 | rna-NM_001183542.1_CBS1585 | cds-NP_014766.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:537513-538907:- | gene-YOR123C_CBS436 | rna-NM_001183542.1_CBS436 | cds-NP_014766.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:531288-532682:- | gene-YOR123C_CBS6412 | rna-NM_001183542.1_CBS6412 | cds-NP_014766.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:538584-539978:- | gene-YOR123C_CBS6413 | rna-NM_001183542.1_CBS6413 | cds-NP_014766.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:553253-554647:- | gene-YOR123C_CENPK1137D | rna-NM_001183542.1_CENPK1137D | cds-NP_014766.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:533608-535002:- | gene-YOR123C_EthanolRed | rna-NM_001183542.1_EthanolRed | cds-NP_014766.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:537304-538698:- | gene-YOR123C_FaliES1 | rna-NM_001183542.1_FaliES1 | cds-NP_014766.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000063.1:20568-21962:+ | gene-YOR123C_JAY291 | rna-NM_001183542.1_JAY291 | cds-NP_014766.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:545346-546740:- | gene-YOR123C_MUCL30387 | rna-NM_001183542.1_MUCL30387 | cds-NP_014766.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:550553-551947:- | gene-YOR123C_MUCL30388 | rna-NM_001183542.1_MUCL30388 | cds-NP_014766.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:540197-541591:- | gene-YOR123C_MUCL39482 | rna-NM_001183542.1_MUCL39482 | cds-NP_014766.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:556242-557636:- | gene-YOR123C_MUCL42920 | rna-NM_001183542.1_MUCL42920 | cds-NP_014766.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:553065-554459:- | gene-YOR123C_NCIM3186 | rna-NM_001183542.1_NCIM3186 | cds-NP_014766.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:546644-548038:- | gene-YOR123C_NCYC1407 | rna-NM_001183542.1_NCYC1407 | cds-NP_014766.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:545647-547041:- | gene-YOR123C_PE2H3 | rna-NM_001183542.1_PE2H3 | cds-NP_014766.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:556024-557418:- | gene-YOR123C_PE2H4 | rna-NM_001183542.1_PE2H4 | cds-NP_014766.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:553176-554570:- | gene-YOR123C_S288C | rna-NM_001183542.1_S288C | cds-NP_014766.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000034.1:82715-84109:- | gene-YOR123C_SA1 | rna-NM_001183542.1_SA1 | cds-NP_014766.1_SA1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:536487-537881:- | gene-YOR123C_ThermosaccDry | rna-NM_001183542.1_ThermosaccDry | cds-NP_014766.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:538592-539986:- | gene-YOR123C_VR1 | rna-NM_001183542.1_VR1 | cds-NP_014766.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:270424-271818:- | gene-YOR123C_ZTW1 | rna-NM_001183542.1_ZTW1 | cds-NP_014766.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:542433-543821:- | gene-YOR123C_Sparadoxus | rna-NM_001183542.1_Sparadoxus | cds-NP_014766.1_Sparadoxus | 89.1 | 99.2 | Verified | 1 | 1 | 1 | False | True | False | False | False |