Gene name: LDH1
Reference locus (S288C): YBR204C
Gene biotype: protein_coding
Description: Lipid droplet hydrolase 1; Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif)
Top 10 interactors (score): TGL3 (0.89); YJU3 (0.858); TGL4 (0.81); YPR147C (0.765); TGL1 (0.763); TGL5 (0.762); LPL1 (0.759); FSH1 (0.703); SCT1 (0.693); SAY1 (0.648); ACK1 (0.621); ROG1 (0.617); LRO1 (0.617); FSH3 (0.613); DGK1 (0.596); DGA1 (0.574); CPT1 (0.567); NTE1 (0.553); CAB5 (0.534); ANR2 (0.485)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:615623-616750:- | gene-YBR204C_AKU4011 | rna-NM_001178552.2_AKU4011 | cds-NP_009763.2_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:605663-606790:- | gene-YBR204C_BG1 | rna-NM_001178552.2_BG1 | cds-NP_009763.2_BG1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:421484-422611:- | gene-YBR204C_Bruggeman | rna-NM_001178552.2_Bruggeman | cds-NP_009763.2_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:620889-622016:- | gene-YBR204C_CAT1 | rna-NM_001178552.2_CAT1 | cds-NP_009763.2_CAT1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:607404-608531:- | gene-YBR204C_CBS1585 | rna-NM_001178552.2_CBS1585 | cds-NP_009763.2_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:614955-616082:- | gene-YBR204C_CBS436 | rna-NM_001178552.2_CBS436 | cds-NP_009763.2_CBS436 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:704013-705140:- | gene-YBR204C_CBS6412 | rna-NM_001178552.2_CBS6412 | cds-NP_009763.2_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:613211-614338:- | gene-YBR204C_CBS6413 | rna-NM_001178552.2_CBS6413 | cds-NP_009763.2_CBS6413 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:626028-627155:- | gene-YBR204C_CENPK1137D | rna-NM_001178552.2_CENPK1137D | cds-NP_009763.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:740572-741699:- | gene-YBR204C_EthanolRed | rna-NM_001178552.2_EthanolRed | cds-NP_009763.2_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:631696-632823:- | gene-YBR204C_FaliES1 | rna-NM_001178552.2_FaliES1 | cds-NP_009763.2_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000023.1:25304-26431:- | gene-YBR204C_JAY291 | rna-NM_001178552.2_JAY291 | cds-NP_009763.2_JAY291 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:620163-621290:- | gene-YBR204C_MUCL30387 | rna-NM_001178552.2_MUCL30387 | cds-NP_009763.2_MUCL30387 | 98.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:637241-638368:- | gene-YBR204C_MUCL30388 | rna-NM_001178552.2_MUCL30388 | cds-NP_009763.2_MUCL30388 | 98.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:605777-606904:- | gene-YBR204C_MUCL39482 | rna-NM_001178552.2_MUCL39482 | cds-NP_009763.2_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:615206-616333:- | gene-YBR204C_MUCL42920 | rna-NM_001178552.2_MUCL42920 | cds-NP_009763.2_MUCL42920 | 98.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:632051-633178:- | gene-YBR204C_NCIM3186 | rna-NM_001178552.2_NCIM3186 | cds-NP_009763.2_NCIM3186 | 98.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:607885-609012:- | gene-YBR204C_NCYC1407 | rna-NM_001178552.2_NCYC1407 | cds-NP_009763.2_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:620505-621632:- | gene-YBR204C_PE2H3 | rna-NM_001178552.2_PE2H3 | cds-NP_009763.2_PE2H3 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:618181-619308:- | gene-YBR204C_PE2H4 | rna-NM_001178552.2_PE2H4 | cds-NP_009763.2_PE2H4 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:632254-633381:- | gene-YBR204C_S288C | rna-NM_001178552.2_S288C | cds-NP_009763.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000080.1:39955-41082:- | gene-YBR204C_SA1 | rna-NM_001178552.2_SA1 | cds-NP_009763.2_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:630706-631833:- | gene-YBR204C_ThermosaccDry | rna-NM_001178552.2_ThermosaccDry | cds-NP_009763.2_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:611871-612998:- | gene-YBR204C_VR1 | rna-NM_001178552.2_VR1 | cds-NP_009763.2_VR1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:605322-606449:- | gene-YBR204C_ZTW1 | rna-NM_001178552.2_ZTW1 | cds-NP_009763.2_ZTW1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:648000-649127:- | gene-YBR204C_Sparadoxus | rna-NM_001178552.2_Sparadoxus | cds-NP_009763.2_Sparadoxus | 88.5 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |