Gene name: LDB19
Reference locus (S288C): YOR322C
Gene biotype: protein_coding
Description: Arrestin-related trafficking adapter 1; Protein LDB19; Alpha-arrestin involved in ubiquitin-dependent endocytosis; regulates endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its targets; involved in the basal internalization and turnover of alpha-factor receptor Ste2p; recruits ubiquitin ligase Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, which affects translocation between the cytosol and the plasma membrane
Top 10 interactors (score): RSP5 (0.987); ROG3 (0.938); ALY2 (0.936); ALY1 (0.933); ECM21 (0.926); BUL1 (0.916); ROD1 (0.916); MUP1 (0.904); STE2 (0.829); BUL2 (0.816); ART10 (0.814); CSR2 (0.813); LYP1 (0.798); SPO23 (0.77); ART5 (0.759); RIM8 (0.737); YPT1 (0.708); JEN1 (0.671); GAP1 (0.666); DIP5 (0.657)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:909097-911553:- | gene-YOR322C_AKU4011 | rna-NM_001183742.3_AKU4011 | cds-NP_014967.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:311101-313557:- | gene-YOR322C_BG1 | rna-NM_001183742.3_BG1 | cds-NP_014967.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:894506-896962:- | gene-YOR322C_Bruggeman | rna-NM_001183742.3_Bruggeman | cds-NP_014967.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:895217-897673:- | gene-YOR322C_CAT1 | rna-NM_001183742.3_CAT1 | cds-NP_014967.3_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:892917-895373:- | gene-YOR322C_CBS1585 | rna-NM_001183742.3_CBS1585 | cds-NP_014967.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:890741-893197:- | gene-YOR322C_CBS436 | rna-NM_001183742.3_CBS436 | cds-NP_014967.3_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:888627-891083:- | gene-YOR322C_CBS6412 | rna-NM_001183742.3_CBS6412 | cds-NP_014967.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:897755-900211:- | gene-YOR322C_CBS6413 | rna-NM_001183742.3_CBS6413 | cds-NP_014967.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:918382-920838:- | gene-YOR322C_CENPK1137D | rna-NM_001183742.3_CENPK1137D | cds-NP_014967.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:885011-887467:- | gene-YOR322C_EthanolRed | rna-NM_001183742.3_EthanolRed | cds-NP_014967.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:890634-893090:- | gene-YOR322C_FaliES1 | rna-NM_001183742.3_FaliES1 | cds-NP_014967.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:110177-112633:+ | gene-YOR322C_JAY291 | rna-NM_001183742.3_JAY291 | cds-NP_014967.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:898745-901201:- | gene-YOR322C_MUCL30387 | rna-NM_001183742.3_MUCL30387 | cds-NP_014967.3_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:906758-909214:- | gene-YOR322C_MUCL30388 | rna-NM_001183742.3_MUCL30388 | cds-NP_014967.3_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:899462-901918:- | gene-YOR322C_MUCL39482 | rna-NM_001183742.3_MUCL39482 | cds-NP_014967.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:908927-911383:- | gene-YOR322C_MUCL42920 | rna-NM_001183742.3_MUCL42920 | cds-NP_014967.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:918495-920951:- | gene-YOR322C_NCIM3186 | rna-NM_001183742.3_NCIM3186 | cds-NP_014967.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:900463-902919:- | gene-YOR322C_NCYC1407 | rna-NM_001183742.3_NCYC1407 | cds-NP_014967.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:898682-901138:- | gene-YOR322C_PE2H3 | rna-NM_001183742.3_PE2H3 | cds-NP_014967.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:915034-917490:- | gene-YOR322C_PE2H4 | rna-NM_001183742.3_PE2H4 | cds-NP_014967.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:918606-921062:- | gene-YOR322C_S288C | rna-NM_001183742.3_S288C | cds-NP_014967.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:28933-31389:- | gene-YOR322C_SA1 | rna-NM_001183742.3_SA1 | cds-NP_014967.3_SA1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:889817-892273:- | gene-YOR322C_ThermosaccDry | rna-NM_001183742.3_ThermosaccDry | cds-NP_014967.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:953102-955558:- | gene-YOR322C_VR1 | rna-NM_001183742.3_VR1 | cds-NP_014967.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:622690-625146:- | gene-YOR322C_ZTW1 | rna-NM_001183742.3_ZTW1 | cds-NP_014967.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:897023-899479:- | gene-YOR322C_Sparadoxus | rna-NM_001183742.3_Sparadoxus | cds-NP_014967.3_Sparadoxus | 89.8 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |