LDB16 (YCL005W)


Gene profile

Gene name: LDB16
Reference locus (S288C): YCL005W
Gene biotype: protein_coding

Description: Protein involved in lipid droplet (LD) assembly; forms a complex with Sei1p at ER-LD contact sites, stabilizing contact sites; ensures that LDs bud from the ER towards the cytosolic side of the membrane; null mutants have decreased net negative cell surface charge and localized accumulation of phosphatidic acid (PA) marker proteins; GFP-fusion protein expression is induced in response to MMS; null mutant can be complemented by the human seipin, BSCL2

Top 10 interactors (score): SEI1 (0.985); PET10 (0.886); DGA1 (0.828); SCS3 (0.778); YFT2 (0.76); OSW5 (0.653); YEH1 (0.633); YNL320W (0.616); PCT1 (0.615); TGL3 (0.614); LRO1 (0.613); PEX30 (0.599); PAH1 (0.571); ARE2 (0.571); LDB18 (0.571); LPP1 (0.563); LDB17 (0.555); ICE2 (0.531); DPP1 (0.525); SPS4 (0.499)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005297.1:102738-103508:+ gene-YCL005W_AKU4011 rna-NM_001178654.1_AKU4011 cds-NP_009922.2_AKU4011 99.2 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000178.1:42525-43295:- gene-YCL005W_BG1 rna-NM_001178654.1_BG1 cds-NP_009922.2_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005505.1:97323-98093:+ gene-YCL005W_Bruggeman rna-NM_001178654.1_Bruggeman cds-NP_009922.2_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005521.1:102473-103243:+ gene-YCL005W_CAT1 rna-NM_001178654.1_CAT1 cds-NP_009922.2_CAT1 99.6 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005361.1:103388-104158:+ gene-YCL005W_CBS1585 rna-NM_001178654.1_CBS1585 cds-NP_009922.2_CBS1585 99.2 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005345.1:108304-109074:+ gene-YCL005W_CBS436 rna-NM_001178654.1_CBS436 cds-NP_009922.2_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005329.1:90847-91617:+ gene-YCL005W_CBS6412 rna-NM_001178654.1_CBS6412 cds-NP_009922.2_CBS6412 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005313.1:102695-103465:+ gene-YCL005W_CBS6413 rna-NM_001178654.1_CBS6413 cds-NP_009922.2_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001524.1:107496-108266:+ gene-YCL005W_CENPK1137D rna-NM_001178654.1_CENPK1137D cds-NP_009922.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005473.1:100757-101527:+ gene-YCL005W_EthanolRed rna-NM_001178654.1_EthanolRed cds-NP_009922.2_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005537.1:103050-103820:+ gene-YCL005W_FaliES1 rna-NM_001178654.1_FaliES1 cds-NP_009922.2_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000126.1:17219-17989:+ gene-YCL005W_JAY291 rna-NM_001178654.1_JAY291 cds-NP_009922.2_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005409.1:95758-96528:+ gene-YCL005W_MUCL30387 rna-NM_001178654.1_MUCL30387 cds-NP_009922.2_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005441.1:95314-96084:+ gene-YCL005W_MUCL30388 rna-NM_001178654.1_MUCL30388 cds-NP_009922.2_MUCL30388 99.8 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005281.1:103805-104575:+ gene-YCL005W_MUCL39482 rna-NM_001178654.1_MUCL39482 cds-NP_009922.2_MUCL39482 99.2 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005425.1:99037-99807:+ gene-YCL005W_MUCL42920 rna-NM_001178654.1_MUCL42920 cds-NP_009922.2_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011812.1:107653-108423:+ gene-YCL005W_NCIM3186 rna-NM_001178654.1_NCIM3186 cds-NP_009922.2_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005265.1:104287-105057:+ gene-YCL005W_NCYC1407 rna-NM_001178654.1_NCYC1407 cds-NP_009922.2_NCYC1407 99.2 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994142.1:108456-109226:+ gene-YCL005W_PE2H3 rna-NM_001178654.1_PE2H3 cds-NP_009922.2_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999874.1:108414-109184:+ gene-YCL005W_PE2H4 rna-NM_001178654.1_PE2H4 cds-NP_009922.2_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001135.5:108021-108791:+ gene-YCL005W_S288C rna-NM_001178654.1_S288C cds-NP_009922.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000073.1:42543-43313:- gene-YCL005W_SA1 rna-NM_001178654.1_SA1 cds-NP_009922.2_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005489.1:103623-104393:+ gene-YCL005W_ThermosaccDry rna-NM_001178654.1_ThermosaccDry cds-NP_009922.2_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005457.1:114263-115033:+ gene-YCL005W_VR1 rna-NM_001178654.1_VR1 cds-NP_009922.2_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000004.1:102560-103330:+ gene-YCL005W_ZTW1 rna-NM_001178654.1_ZTW1 cds-NP_009922.2_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047489.1:132798-133568:+ gene-YCL005W_Sparadoxus rna-NM_001178654.1_Sparadoxus cds-NP_009922.2_Sparadoxus 90.9 100.0 Verified 1 1 1 False True False False False

Additional files