Gene name: LCL3
Reference locus (S288C): YGL085W
Gene biotype: protein_coding
Description: Probable endonuclease LCL3; Putative protein of unknown function; mutant has long chronological lifespan; has homology to Staphylococcus aureus nuclease; GFP-fusion protein localizes to mitochondria; is induced in response to the DNA-damaging agent MMS
Top 10 interactors (score): LCL2 (0.766); PET127 (0.712); LCL1 (0.7); DPH5 (0.68); TRZ1 (0.677); DCW1 (0.617); ARC35 (0.615); MEK1 (0.528); BNA2 (0.524); BNA1 (0.524); FCY2 (0.505); HSL7 (0.505); HOP2 (0.483); SGF29 (0.482); ADE4 (0.451); UBI4 (0.439); BAS1 (0.432); MCX1 (0.417); NSI1 (0.402); REB1 (0.402)
Homologues (species, bitscore): Tudor-SN (Drosophila melanogaster, 52.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:352621-353445:+ | gene-YGL085W_AKU4011 | rna-NM_001180950.1_AKU4011 | cds-NP_011430.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:51960-52784:- | gene-YGL085W_BG1 | rna-NM_001180950.1_BG1 | cds-NP_011430.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:355115-355939:+ | gene-YGL085W_Bruggeman | rna-NM_001180950.1_Bruggeman | cds-NP_011430.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:352017-352841:+ | gene-YGL085W_CAT1 | rna-NM_001180950.1_CAT1 | cds-NP_011430.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:355946-356770:+ | gene-YGL085W_CBS1585 | rna-NM_001180950.1_CBS1585 | cds-NP_011430.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:350230-351054:+ | gene-YGL085W_CBS436 | rna-NM_001180950.1_CBS436 | cds-NP_011430.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:340327-341151:+ | gene-YGL085W_CBS6412 | rna-NM_001180950.1_CBS6412 | cds-NP_011430.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:350251-351075:+ | gene-YGL085W_CBS6413 | rna-NM_001180950.1_CBS6413 | cds-NP_011430.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:349805-350629:+ | gene-YGL085W_CENPK1137D | rna-NM_001180950.1_CENPK1137D | cds-NP_011430.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:341705-342529:+ | gene-YGL085W_EthanolRed | rna-NM_001180950.1_EthanolRed | cds-NP_011430.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:344266-345090:+ | gene-YGL085W_FaliES1 | rna-NM_001180950.1_FaliES1 | cds-NP_011430.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000369.1:29889-30713:+ | gene-YGL085W_JAY291 | rna-NM_001180950.1_JAY291 | cds-NP_011430.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:352092-352916:+ | gene-YGL085W_MUCL30387 | rna-NM_001180950.1_MUCL30387 | cds-NP_011430.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:355076-355900:+ | gene-YGL085W_MUCL30388 | rna-NM_001180950.1_MUCL30388 | cds-NP_011430.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:352474-353298:+ | gene-YGL085W_MUCL39482 | rna-NM_001180950.1_MUCL39482 | cds-NP_011430.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:357001-357825:+ | gene-YGL085W_MUCL42920 | rna-NM_001180950.1_MUCL42920 | cds-NP_011430.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:349616-350440:+ | gene-YGL085W_NCIM3186 | rna-NM_001180950.1_NCIM3186 | cds-NP_011430.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:344009-344833:+ | gene-YGL085W_NCYC1407 | rna-NM_001180950.1_NCYC1407 | cds-NP_011430.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:345655-346479:+ | gene-YGL085W_PE2H3 | rna-NM_001180950.1_PE2H3 | cds-NP_011430.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:350640-351464:+ | gene-YGL085W_PE2H4 | rna-NM_001180950.1_PE2H4 | cds-NP_011430.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:349616-350440:+ | gene-YGL085W_S288C | rna-NM_001180950.1_S288C | cds-NP_011430.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000089.1:27030-27854:+ | gene-YGL085W_SA1 | rna-NM_001180950.1_SA1 | cds-NP_011430.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:344519-345343:+ | gene-YGL085W_ThermosaccDry | rna-NM_001180950.1_ThermosaccDry | cds-NP_011430.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:454382-455206:+ | gene-YGL085W_VR1 | rna-NM_001180950.1_VR1 | cds-NP_011430.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:341871-342695:+ | gene-YGL085W_ZTW1 | rna-NM_001180950.1_ZTW1 | cds-NP_011430.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:347513-348337:+ | gene-YGL085W_Sparadoxus | rna-NM_001180950.1_Sparadoxus | cds-NP_011430.1_Sparadoxus | 90.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |