Gene name: LCL2
Reference locus (S288C): YLR104W
Gene biotype: protein_coding
Description: Long chronological lifespan protein 2; Putative protein of unknown function; mutant is deficient in cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole
Top 10 interactors (score): JEM1 (0.919); HRD1 (0.841); YIL152W (0.769); LCL3 (0.766); EMP65 (0.745); MUM2 (0.698); YDL012C (0.672); LCL1 (0.651); TRP4 (0.616); YJR039W (0.612); PER33 (0.593); NDL1 (0.575); DCW1 (0.571); PBP2 (0.571); FAR7 (0.567); NIT1 (0.567); RCF1 (0.521); PET122 (0.499); USA1 (0.468); HAC1 (0.466)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:329089-329484:+ | gene-YLR104W_AKU4011 | rna-NM_001181991.1_AKU4011 | cds-NP_013205.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:292265-292660:+ | gene-YLR104W_BG1 | rna-NM_001181991.1_BG1 | cds-NP_013205.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:338938-339333:+ | gene-YLR104W_Bruggeman | rna-NM_001181991.1_Bruggeman | cds-NP_013205.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:339286-339681:+ | gene-YLR104W_CAT1 | rna-NM_001181991.1_CAT1 | cds-NP_013205.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:336231-336626:+ | gene-YLR104W_CBS1585 | rna-NM_001181991.1_CBS1585 | cds-NP_013205.1_CBS1585 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:326794-327189:+ | gene-YLR104W_CBS436 | rna-NM_001181991.1_CBS436 | cds-NP_013205.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:334650-335045:+ | gene-YLR104W_CBS6412 | rna-NM_001181991.1_CBS6412 | cds-NP_013205.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:336497-336892:+ | gene-YLR104W_CBS6413 | rna-NM_001181991.1_CBS6413 | cds-NP_013205.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:331609-332004:+ | gene-YLR104W_CENPK1137D | rna-NM_001181991.1_CENPK1137D | cds-NP_013205.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:328648-329043:+ | gene-YLR104W_EthanolRed | rna-NM_001181991.1_EthanolRed | cds-NP_013205.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:328467-328862:+ | gene-YLR104W_FaliES1 | rna-NM_001181991.1_FaliES1 | cds-NP_013205.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000129.1:103394-103789:+ | gene-YLR104W_JAY291 | rna-NM_001181991.1_JAY291 | cds-NP_013205.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:336314-336709:+ | gene-YLR104W_MUCL30387 | rna-NM_001181991.1_MUCL30387 | cds-NP_013205.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:343982-344377:+ | gene-YLR104W_MUCL30388 | rna-NM_001181991.1_MUCL30388 | cds-NP_013205.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:336739-337134:+ | gene-YLR104W_MUCL39482 | rna-NM_001181991.1_MUCL39482 | cds-NP_013205.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:336643-337038:+ | gene-YLR104W_MUCL42920 | rna-NM_001181991.1_MUCL42920 | cds-NP_013205.1_MUCL42920 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:346559-346954:+ | gene-YLR104W_NCIM3186 | rna-NM_001181991.1_NCIM3186 | cds-NP_013205.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:328802-329197:+ | gene-YLR104W_NCYC1407 | rna-NM_001181991.1_NCYC1407 | cds-NP_013205.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:334559-334954:+ | gene-YLR104W_PE2H3 | rna-NM_001181991.1_PE2H3 | cds-NP_013205.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:334300-334695:+ | gene-YLR104W_PE2H4 | rna-NM_001181991.1_PE2H4 | cds-NP_013205.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:346585-346980:+ | gene-YLR104W_S288C | rna-NM_001181991.1_S288C | cds-NP_013205.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000033.1:27112-27507:- | gene-YLR104W_SA1 | rna-NM_001181991.1_SA1 | cds-NP_013205.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:328640-329035:+ | gene-YLR104W_ThermosaccDry | rna-NM_001181991.1_ThermosaccDry | cds-NP_013205.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:342800-343195:+ | gene-YLR104W_VR1 | rna-NM_001181991.1_VR1 | cds-NP_013205.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:328064-328459:+ | gene-YLR104W_ZTW1 | rna-NM_001181991.1_ZTW1 | cds-NP_013205.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:336836-337231:+ | gene-YLR104W_Sparadoxus | rna-NM_001181991.1_Sparadoxus | cds-NP_013205.1_Sparadoxus | 86.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |