LCL2 (YLR104W)


Gene profile

Gene name: LCL2
Reference locus (S288C): YLR104W
Gene biotype: protein_coding

Description: Long chronological lifespan protein 2; Putative protein of unknown function; mutant is deficient in cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole

Top 10 interactors (score): JEM1 (0.919); HRD1 (0.841); YIL152W (0.769); LCL3 (0.766); EMP65 (0.745); MUM2 (0.698); YDL012C (0.672); LCL1 (0.651); TRP4 (0.616); YJR039W (0.612); PER33 (0.593); NDL1 (0.575); DCW1 (0.571); PBP2 (0.571); FAR7 (0.567); NIT1 (0.567); RCF1 (0.521); PET122 (0.499); USA1 (0.468); HAC1 (0.466)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:329089-329484:+ gene-YLR104W_AKU4011 rna-NM_001181991.1_AKU4011 cds-NP_013205.1_AKU4011 99.4 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000212.1:292265-292660:+ gene-YLR104W_BG1 rna-NM_001181991.1_BG1 cds-NP_013205.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:338938-339333:+ gene-YLR104W_Bruggeman rna-NM_001181991.1_Bruggeman cds-NP_013205.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:339286-339681:+ gene-YLR104W_CAT1 rna-NM_001181991.1_CAT1 cds-NP_013205.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:336231-336626:+ gene-YLR104W_CBS1585 rna-NM_001181991.1_CBS1585 cds-NP_013205.1_CBS1585 98.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:326794-327189:+ gene-YLR104W_CBS436 rna-NM_001181991.1_CBS436 cds-NP_013205.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:334650-335045:+ gene-YLR104W_CBS6412 rna-NM_001181991.1_CBS6412 cds-NP_013205.1_CBS6412 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:336497-336892:+ gene-YLR104W_CBS6413 rna-NM_001181991.1_CBS6413 cds-NP_013205.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:331609-332004:+ gene-YLR104W_CENPK1137D rna-NM_001181991.1_CENPK1137D cds-NP_013205.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:328648-329043:+ gene-YLR104W_EthanolRed rna-NM_001181991.1_EthanolRed cds-NP_013205.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:328467-328862:+ gene-YLR104W_FaliES1 rna-NM_001181991.1_FaliES1 cds-NP_013205.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000129.1:103394-103789:+ gene-YLR104W_JAY291 rna-NM_001181991.1_JAY291 cds-NP_013205.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:336314-336709:+ gene-YLR104W_MUCL30387 rna-NM_001181991.1_MUCL30387 cds-NP_013205.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:343982-344377:+ gene-YLR104W_MUCL30388 rna-NM_001181991.1_MUCL30388 cds-NP_013205.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:336739-337134:+ gene-YLR104W_MUCL39482 rna-NM_001181991.1_MUCL39482 cds-NP_013205.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:336643-337038:+ gene-YLR104W_MUCL42920 rna-NM_001181991.1_MUCL42920 cds-NP_013205.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:346559-346954:+ gene-YLR104W_NCIM3186 rna-NM_001181991.1_NCIM3186 cds-NP_013205.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:328802-329197:+ gene-YLR104W_NCYC1407 rna-NM_001181991.1_NCYC1407 cds-NP_013205.1_NCYC1407 99.4 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:334559-334954:+ gene-YLR104W_PE2H3 rna-NM_001181991.1_PE2H3 cds-NP_013205.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:334300-334695:+ gene-YLR104W_PE2H4 rna-NM_001181991.1_PE2H4 cds-NP_013205.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:346585-346980:+ gene-YLR104W_S288C rna-NM_001181991.1_S288C cds-NP_013205.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000033.1:27112-27507:- gene-YLR104W_SA1 rna-NM_001181991.1_SA1 cds-NP_013205.1_SA1 99.2 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:328640-329035:+ gene-YLR104W_ThermosaccDry rna-NM_001181991.1_ThermosaccDry cds-NP_013205.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:342800-343195:+ gene-YLR104W_VR1 rna-NM_001181991.1_VR1 cds-NP_013205.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000023.1:328064-328459:+ gene-YLR104W_ZTW1 rna-NM_001181991.1_ZTW1 cds-NP_013205.1_ZTW1 99.4 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:336836-337231:+ gene-YLR104W_Sparadoxus rna-NM_001181991.1_Sparadoxus cds-NP_013205.1_Sparadoxus 86.6 100.0 Verified 1 1 1 False True False False False

Additional files