LCD1 (YDR499W)


Gene profile

Gene name: LCD1
Reference locus (S288C): YDR499W
Gene biotype: protein_coding

Description: Essential protein required for the DNA integrity checkpoint pathways; interacts physically with Mec1p; putative homolog of S. pombe Rad26 and human ATRIP; forms nuclear foci upon DNA replication stress

Top 10 interactors (score): MEC1 (0.999); RFA1 (0.989); RAD53 (0.984); CHK1 (0.977); RAD9 (0.967); DNA2 (0.964); MRC1 (0.96); DPB11 (0.944); TEL1 (0.918); SML1 (0.905); DDC1 (0.894); MEC3 (0.893); PML39 (0.858); RFA2 (0.833); URA2 (0.827); EXO1 (0.826); SIR3 (0.822); SGS1 (0.813); CSM3 (0.81); TOF1 (0.81)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:1387816-1390059:+ gene-YDR499W_AKU4011 rna-NM_001180807.3_AKU4011 cds-NP_010787.3_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000073.1:29375-31618:+ gene-YDR499W_BG1 rna-NM_001180807.3_BG1 cds-NP_010787.3_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:1419136-1421379:+ gene-YDR499W_Bruggeman rna-NM_001180807.3_Bruggeman cds-NP_010787.3_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:1396315-1398558:+ gene-YDR499W_CAT1 rna-NM_001180807.3_CAT1 cds-NP_010787.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:1382058-1384301:+ gene-YDR499W_CBS1585 rna-NM_001180807.3_CBS1585 cds-NP_010787.3_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:1401412-1403655:+ gene-YDR499W_CBS436 rna-NM_001180807.3_CBS436 cds-NP_010787.3_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:1377700-1379943:+ gene-YDR499W_CBS6412 rna-NM_001180807.3_CBS6412 cds-NP_010787.3_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:1400715-1402958:+ gene-YDR499W_CBS6413 rna-NM_001180807.3_CBS6413 cds-NP_010787.3_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:1446524-1448767:+ gene-YDR499W_CENPK1137D rna-NM_001180807.3_CENPK1137D cds-NP_010787.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:1391105-1393348:+ gene-YDR499W_EthanolRed rna-NM_001180807.3_EthanolRed cds-NP_010787.3_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:1394658-1396901:+ gene-YDR499W_FaliES1 rna-NM_001180807.3_FaliES1 cds-NP_010787.3_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000026.1:92909-95152:+ gene-YDR499W_JAY291 rna-NM_001180807.3_JAY291 cds-NP_010787.3_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:1401661-1403904:+ gene-YDR499W_MUCL30387 rna-NM_001180807.3_MUCL30387 cds-NP_010787.3_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:1383654-1385897:+ gene-YDR499W_MUCL30388 rna-NM_001180807.3_MUCL30388 cds-NP_010787.3_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:1373543-1375786:+ gene-YDR499W_MUCL39482 rna-NM_001180807.3_MUCL39482 cds-NP_010787.3_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:1316334-1318577:+ gene-YDR499W_MUCL42920 rna-NM_001180807.3_MUCL42920 cds-NP_010787.3_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:1447753-1449996:+ gene-YDR499W_NCIM3186 rna-NM_001180807.3_NCIM3186 cds-NP_010787.3_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:1387329-1389572:+ gene-YDR499W_NCYC1407 rna-NM_001180807.3_NCYC1407 cds-NP_010787.3_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:1398176-1400419:+ gene-YDR499W_PE2H3 rna-NM_001180807.3_PE2H3 cds-NP_010787.3_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:1403751-1405994:+ gene-YDR499W_PE2H4 rna-NM_001180807.3_PE2H4 cds-NP_010787.3_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:1447830-1450073:+ gene-YDR499W_S288C rna-NM_001180807.3_S288C cds-NP_010787.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000004.1:167060-169303:- gene-YDR499W_SA1 rna-NM_001180807.3_SA1 cds-NP_010787.3_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:1398880-1401123:+ gene-YDR499W_ThermosaccDry rna-NM_001180807.3_ThermosaccDry cds-NP_010787.3_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:1414621-1416864:+ gene-YDR499W_VR1 rna-NM_001180807.3_VR1 cds-NP_010787.3_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000008.1:441549-443792:+ gene-YDR499W_ZTW1 rna-NM_001180807.3_ZTW1 cds-NP_010787.3_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:1401684-1403924:+ gene-YDR499W_Sparadoxus rna-NM_001180807.3_Sparadoxus cds-NP_010787.3_Sparadoxus 89.5 99.8 Verified 1 1 1 False True False False False

Additional files