LCB5 (YLR260W)


Gene profile

Gene name: LCB5
Reference locus (S288C): YLR260W
Gene biotype: protein_coding

Description: Minor sphingoid long-chain base kinase; possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules; LCB5 has a paralog, LCB4, that arose from the whole genome duplication

Top 10 interactors (score): YSR3 (0.995); LCB3 (0.994); DPL1 (0.993); LAG1 (0.985); YPC1 (0.985); LAC1 (0.985); YDC1 (0.98); LCB4 (0.957); SUR2 (0.949); TSC10 (0.923); PKC1 (0.906); LCB1 (0.906); LCB2 (0.838); ISC1 (0.798); CSG2 (0.721); SCS7 (0.692); TVP23 (0.671); PHS1 (0.665); ERG13 (0.66); EST2 (0.644)

Homologues (species, bitscore): SPHK1 (Homo sapiens, 129.4); Sphk1 (Mus musculus, 122.5); sphk2 (Danio rerio, 112.1); sphk1 (Xenopus tropicalis, 137.1); Sk2 (Drosophila melanogaster, 133.3); sphk-1 (Caenorhabditis elegans, 83.2); SPHK1 (Arabidopsis thaliana, 132.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:614133-616169:+ gene-YLR260W_AKU4011 rna-NM_001182147.1_AKU4011 cds-NP_013361.1_AKU4011 98.4 98.6 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000170.1:115722-117758:- gene-YLR260W_BG1 rna-NM_001182147.1_BG1 cds-NP_013361.1_BG1 98.4 98.6 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:648378-650413:+ gene-YLR260W_Bruggeman rna-NM_001182147.1_Bruggeman cds-NP_013361.1_Bruggeman 98.3 98.6 Unannotated 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:647523-649586:+ gene-YLR260W_CAT1 rna-NM_001182147.1_CAT1 cds-NP_013361.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:649628-651664:+ gene-YLR260W_CBS1585 rna-NM_001182147.1_CBS1585 cds-NP_013361.1_CBS1585 98.4 98.6 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:633852-635888:+ gene-YLR260W_CBS436 rna-NM_001182147.1_CBS436 cds-NP_013361.1_CBS436 98.4 98.6 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:612603-614639:+ gene-YLR260W_CBS6412 rna-NM_001182147.1_CBS6412 cds-NP_013361.1_CBS6412 98.4 98.6 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:649924-651960:+ gene-YLR260W_CBS6413 rna-NM_001182147.1_CBS6413 cds-NP_013361.1_CBS6413 98.3 98.6 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:650453-652489:+ gene-YLR260W_CENPK1137D rna-NM_001182147.1_CENPK1137D cds-NP_013361.1_CENPK1137D 98.4 98.6 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:608234-610297:+ gene-YLR260W_EthanolRed rna-NM_001182147.1_EthanolRed cds-NP_013361.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:637071-639134:+ gene-YLR260W_FaliES1 rna-NM_001182147.1_FaliES1 cds-NP_013361.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000136.1:20220-22282:- gene-YLR260W_JAY291 rna-NM_001182147.1_JAY291 cds-NP_013361.1_JAY291 99.7 99.9 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:649238-651273:+ gene-YLR260W_MUCL30387 rna-NM_001182147.1_MUCL30387 cds-NP_013361.1_MUCL30387 98.3 98.6 Unannotated 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:654002-656038:+ gene-YLR260W_MUCL30388 rna-NM_001182147.1_MUCL30388 cds-NP_013361.1_MUCL30388 98.3 98.6 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:650609-652645:+ gene-YLR260W_MUCL39482 rna-NM_001182147.1_MUCL39482 cds-NP_013361.1_MUCL39482 98.4 98.6 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:645381-647417:+ gene-YLR260W_MUCL42920 rna-NM_001182147.1_MUCL42920 cds-NP_013361.1_MUCL42920 98.4 98.6 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:665818-667881:+ gene-YLR260W_NCIM3186 rna-NM_001182147.1_NCIM3186 cds-NP_013361.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:637596-639632:+ gene-YLR260W_NCYC1407 rna-NM_001182147.1_NCYC1407 cds-NP_013361.1_NCYC1407 98.4 98.6 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:641329-643392:+ gene-YLR260W_PE2H3 rna-NM_001182147.1_PE2H3 cds-NP_013361.1_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:641073-643136:+ gene-YLR260W_PE2H4 rna-NM_001182147.1_PE2H4 cds-NP_013361.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:665844-667907:+ gene-YLR260W_S288C rna-NM_001182147.1_S288C cds-NP_013361.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000013.1:20465-22528:- gene-YLR260W_SA1 rna-NM_001182147.1_SA1 cds-NP_013361.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:639079-641142:+ gene-YLR260W_ThermosaccDry rna-NM_001182147.1_ThermosaccDry cds-NP_013361.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:650443-652479:+ gene-YLR260W_VR1 rna-NM_001182147.1_VR1 cds-NP_013361.1_VR1 98.4 98.6 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000024.1:163391-165454:+ gene-YLR260W_ZTW1 rna-NM_001182147.1_ZTW1 cds-NP_013361.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:624929-626971:+ gene-YLR260W_Sparadoxus rna-NM_001182147.1_Sparadoxus cds-NP_013361.1_Sparadoxus 88.7 98.6 Verified 1 1 1 False True False False False

Additional files