LCB3 (YJL134W)


Gene profile

Gene name: LCB3
Reference locus (S288C): YJL134W
Gene biotype: protein_coding

Description: Long-chain base-1-phosphate phosphatase; specific for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids; LCB3 has a paralog, YSR3, that arose from the whole genome duplication

Top 10 interactors (score): DPL1 (0.999); LCB4 (0.997); SUR2 (0.997); LCB5 (0.994); LAG1 (0.987); LAC1 (0.987); YDC1 (0.977); YSR3 (0.954); TSC10 (0.94); LCB2 (0.866); LCB1 (0.855); ELO3 (0.823); SVF1 (0.813); YPC1 (0.786); YOR072W (0.748); LIP1 (0.741); ISC1 (0.695); ORM2 (0.69); CKA2 (0.638); FSH3 (0.615)

Homologues (species, bitscore): SGPP1 (Homo sapiens, 75.5); Sgpp2 (Mus musculus, 76.6); SGPP2 (Danio rerio, 64.3); SGPP2 (Xenopus tropicalis, 73.9); AT3G58490 (Arabidopsis thaliana, 113.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:146482-147711:+ gene-YJL134W_AKU4011 rna-NM_001181567.1_AKU4011 cds-NP_012401.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:466008-467237:- gene-YJL134W_BG1 rna-NM_001181567.1_BG1 cds-NP_012401.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:158567-159796:+ gene-YJL134W_Bruggeman rna-NM_001181567.1_Bruggeman cds-NP_012401.1_Bruggeman 99.9 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:162355-163584:+ gene-YJL134W_CAT1 rna-NM_001181567.1_CAT1 cds-NP_012401.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:152116-153345:+ gene-YJL134W_CBS1585 rna-NM_001181567.1_CBS1585 cds-NP_012401.1_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:176866-178095:+ gene-YJL134W_CBS436 rna-NM_001181567.1_CBS436 cds-NP_012401.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:148134-149363:+ gene-YJL134W_CBS6412 rna-NM_001181567.1_CBS6412 cds-NP_012401.1_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:149592-150821:+ gene-YJL134W_CBS6413 rna-NM_001181567.1_CBS6413 cds-NP_012401.1_CBS6413 99.4 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:140657-141886:+ gene-YJL134W_CENPK1137D rna-NM_001181567.1_CENPK1137D cds-NP_012401.1_CENPK1137D 99.3 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:150466-151695:+ gene-YJL134W_EthanolRed rna-NM_001181567.1_EthanolRed cds-NP_012401.1_EthanolRed 99.5 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:156118-157347:+ gene-YJL134W_FaliES1 rna-NM_001181567.1_FaliES1 cds-NP_012401.1_FaliES1 99.5 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000099.1:37298-38527:+ gene-YJL134W_JAY291 rna-NM_001181567.1_JAY291 cds-NP_012401.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:160836-162065:+ gene-YJL134W_MUCL30387 rna-NM_001181567.1_MUCL30387 cds-NP_012401.1_MUCL30387 99.9 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:156887-158116:+ gene-YJL134W_MUCL30388 rna-NM_001181567.1_MUCL30388 cds-NP_012401.1_MUCL30388 99.9 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:151064-152293:+ gene-YJL134W_MUCL39482 rna-NM_001181567.1_MUCL39482 cds-NP_012401.1_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:156627-157856:+ gene-YJL134W_MUCL42920 rna-NM_001181567.1_MUCL42920 cds-NP_012401.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:158167-159396:+ gene-YJL134W_NCIM3186 rna-NM_001181567.1_NCIM3186 cds-NP_012401.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:149470-150699:+ gene-YJL134W_NCYC1407 rna-NM_001181567.1_NCYC1407 cds-NP_012401.1_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:162275-163504:+ gene-YJL134W_PE2H3 rna-NM_001181567.1_PE2H3 cds-NP_012401.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:161919-163148:+ gene-YJL134W_PE2H4 rna-NM_001181567.1_PE2H4 cds-NP_012401.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:158188-159417:+ gene-YJL134W_S288C rna-NM_001181567.1_S288C cds-NP_012401.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000085.1:39755-40984:- gene-YJL134W_SA1 rna-NM_001181567.1_SA1 cds-NP_012401.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:149309-150538:+ gene-YJL134W_ThermosaccDry rna-NM_001181567.1_ThermosaccDry cds-NP_012401.1_ThermosaccDry 99.5 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:156391-157620:+ gene-YJL134W_VR1 rna-NM_001181567.1_VR1 cds-NP_012401.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:136602-137831:+ gene-YJL134W_ZTW1 rna-NM_001181567.1_ZTW1 cds-NP_012401.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:161854-163083:+ gene-YJL134W_Sparadoxus rna-NM_001181567.1_Sparadoxus cds-NP_012401.1_Sparadoxus 91.0 100.0 Verified 1 1 1 False True False False False

Additional files