Gene name: LCB2
Reference locus (S288C): YDR062W
Gene biotype: protein_coding
Description: Component of serine palmitoyltransferase; responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family
Top 10 interactors (score): LCB1 (0.999); TSC3 (0.998); ORM2 (0.997); TSC10 (0.997); ORM1 (0.993); SAC1 (0.985); LAC1 (0.946); TRP5 (0.933); LAG1 (0.921); LCB4 (0.908); RLI1 (0.904); YPC1 (0.892); YDC1 (0.878); SUR2 (0.875); DBF4 (0.872); LCB3 (0.866); ISC1 (0.865); CSG2 (0.864); SHM2 (0.853); SHM1 (0.853)
Homologues (species, bitscore): SPTLC2 (Homo sapiens, 482.6); Sptlc2 (Mus musculus, 485.3); sptlc2a (Danio rerio, 483.8); sptlc2 (Xenopus tropicalis, 491.9); lace (Drosophila melanogaster, 424.9); sptl-2 (Caenorhabditis elegans, 437.2); LCB2 (Arabidopsis thaliana, 434.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:554017-555702:+ | gene-YDR062W_AKU4011 | rna-NM_001180370.1_AKU4011 | cds-NP_010347.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:569689-571374:- | gene-YDR062W_BG1 | rna-NM_001180370.1_BG1 | cds-NP_010347.1_BG1 | 92.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:586323-588008:+ | gene-YDR062W_Bruggeman | rna-NM_001180370.1_Bruggeman | cds-NP_010347.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:569347-571032:+ | gene-YDR062W_CAT1 | rna-NM_001180370.1_CAT1 | cds-NP_010347.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:544971-546656:+ | gene-YDR062W_CBS1585 | rna-NM_001180370.1_CBS1585 | cds-NP_010347.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:570137-571822:+ | gene-YDR062W_CBS436 | rna-NM_001180370.1_CBS436 | cds-NP_010347.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:541383-543068:+ | gene-YDR062W_CBS6412 | rna-NM_001180370.1_CBS6412 | cds-NP_010347.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:570051-571736:+ | gene-YDR062W_CBS6413 | rna-NM_001180370.1_CBS6413 | cds-NP_010347.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:575440-577125:+ | gene-YDR062W_CENPK1137D | rna-NM_001180370.1_CENPK1137D | cds-NP_010347.1_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:555834-557519:+ | gene-YDR062W_EthanolRed | rna-NM_001180370.1_EthanolRed | cds-NP_010347.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:562280-563965:+ | gene-YDR062W_FaliES1 | rna-NM_001180370.1_FaliES1 | cds-NP_010347.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000358.1:66840-68525:- | gene-YDR062W_JAY291 | rna-NM_001180370.1_JAY291 | cds-NP_010347.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:571016-572701:+ | gene-YDR062W_MUCL30387 | rna-NM_001180370.1_MUCL30387 | cds-NP_010347.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:561406-563091:+ | gene-YDR062W_MUCL30388 | rna-NM_001180370.1_MUCL30388 | cds-NP_010347.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:546341-548026:+ | gene-YDR062W_MUCL39482 | rna-NM_001180370.1_MUCL39482 | cds-NP_010347.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:476816-478501:+ | gene-YDR062W_MUCL42920 | rna-NM_001180370.1_MUCL42920 | cds-NP_010347.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:576397-578082:+ | gene-YDR062W_NCIM3186 | rna-NM_001180370.1_NCIM3186 | cds-NP_010347.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:545275-546960:+ | gene-YDR062W_NCYC1407 | rna-NM_001180370.1_NCYC1407 | cds-NP_010347.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:564907-566592:+ | gene-YDR062W_PE2H3 | rna-NM_001180370.1_PE2H3 | cds-NP_010347.1_PE2H3 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:564212-565897:+ | gene-YDR062W_PE2H4 | rna-NM_001180370.1_PE2H4 | cds-NP_010347.1_PE2H4 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:576474-578159:+ | gene-YDR062W_S288C | rna-NM_001180370.1_S288C | cds-NP_010347.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000011.1:67332-69017:- | gene-YDR062W_SA1 | rna-NM_001180370.1_SA1 | cds-NP_010347.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:561973-563658:+ | gene-YDR062W_ThermosaccDry | rna-NM_001180370.1_ThermosaccDry | cds-NP_010347.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:574721-576406:+ | gene-YDR062W_VR1 | rna-NM_001180370.1_VR1 | cds-NP_010347.1_VR1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:559624-561309:+ | gene-YDR062W_ZTW1 | rna-NM_001180370.1_ZTW1 | cds-NP_010347.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:564482-566167:+ | gene-YDR062W_Sparadoxus | rna-NM_001180370.1_Sparadoxus | cds-NP_010347.1_Sparadoxus | 92.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |