Gene name: LCB1
Reference locus (S288C): YMR296C
Gene biotype: protein_coding
Description: Serine c-palmitoyltransferase lcb1; Component of serine palmitoyltransferase; responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
Top 10 interactors (score): LCB2 (0.999); ORM2 (0.998); ORM1 (0.997); TSC3 (0.996); TSC10 (0.994); SAC1 (0.991); ISC1 (0.956); TRP5 (0.939); YPC1 (0.919); LAC1 (0.917); LAG1 (0.916); LCB5 (0.906); YDC1 (0.895); LCB4 (0.889); TOR1 (0.857); LCB3 (0.855); SHM2 (0.854); SHM1 (0.854); TOR2 (0.847); SUR2 (0.846)
Homologues (species, bitscore): SPTLC1 (Homo sapiens, 275.8); Sptlc1 (Mus musculus, 282.7); sptlc1 (Danio rerio, 282.3); sptlc1 (Xenopus tropicalis, 289.3); Spt-I (Drosophila melanogaster, 265.4); sptl-1 (Caenorhabditis elegans, 284.6); LCB1 (Arabidopsis thaliana, 258.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:898263-899939:- | gene-YMR296C_AKU4011 | rna-NM_001182805.1_AKU4011 | cds-NP_014025.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:53763-55439:+ | gene-YMR296C_BG1 | rna-NM_001182805.1_BG1 | cds-NP_014025.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:843473-845149:- | gene-YMR296C_Bruggeman | rna-NM_001182805.1_Bruggeman | cds-NP_014025.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:846756-848432:- | gene-YMR296C_CAT1 | rna-NM_001182805.1_CAT1 | cds-NP_014025.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:830514-832190:- | gene-YMR296C_CBS1585 | rna-NM_001182805.1_CBS1585 | cds-NP_014025.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:852828-854504:- | gene-YMR296C_CBS436 | rna-NM_001182805.1_CBS436 | cds-NP_014025.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:942089-943765:- | gene-YMR296C_CBS6412 | rna-NM_001182805.1_CBS6412 | cds-NP_014025.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:829633-831309:- | gene-YMR296C_CBS6413 | rna-NM_001182805.1_CBS6413 | cds-NP_014025.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:853757-855433:- | gene-YMR296C_CENPK1137D | rna-NM_001182805.1_CENPK1137D | cds-NP_014025.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:890955-892631:- | gene-YMR296C_EthanolRed | rna-NM_001182805.1_EthanolRed | cds-NP_014025.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:836982-838658:- | gene-YMR296C_FaliES1 | rna-NM_001182805.1_FaliES1 | cds-NP_014025.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000262.1:13075-14751:+ | gene-YMR296C_JAY291 | rna-NM_001182805.1_JAY291 | cds-NP_014025.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:837297-838973:- | gene-YMR296C_MUCL30387 | rna-NM_001182805.1_MUCL30387 | cds-NP_014025.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:846689-848365:- | gene-YMR296C_MUCL30388 | rna-NM_001182805.1_MUCL30388 | cds-NP_014025.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:831579-833255:- | gene-YMR296C_MUCL39482 | rna-NM_001182805.1_MUCL39482 | cds-NP_014025.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:840401-842077:- | gene-YMR296C_MUCL42920 | rna-NM_001182805.1_MUCL42920 | cds-NP_014025.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:859169-860845:- | gene-YMR296C_NCIM3186 | rna-NM_001182805.1_NCIM3186 | cds-NP_014025.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:831233-832909:- | gene-YMR296C_NCYC1407 | rna-NM_001182805.1_NCYC1407 | cds-NP_014025.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:847053-848729:- | gene-YMR296C_PE2H3 | rna-NM_001182805.1_PE2H3 | cds-NP_014025.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:843024-844700:- | gene-YMR296C_PE2H4 | rna-NM_001182805.1_PE2H4 | cds-NP_014025.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:859215-860891:- | gene-YMR296C_S288C | rna-NM_001182805.1_S288C | cds-NP_014025.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000036.1:37010-38686:- | gene-YMR296C_SA1 | rna-NM_001182805.1_SA1 | cds-NP_014025.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:833150-834826:- | gene-YMR296C_ThermosaccDry | rna-NM_001182805.1_ThermosaccDry | cds-NP_014025.1_ThermosaccDry | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:846906-848582:- | gene-YMR296C_VR1 | rna-NM_001182805.1_VR1 | cds-NP_014025.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000028.1:248388-250064:- | gene-YMR296C_ZTW1 | rna-NM_001182805.1_ZTW1 | cds-NP_014025.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:851770-853446:- | gene-YMR296C_Sparadoxus | rna-NM_001182805.1_Sparadoxus | cds-NP_014025.1_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |